Results 161 to 170 of about 440,184 (328)

A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms [PDF]

, 2011
Background: Alterations in the DNA methylation pattern are a hallmark of leukemias and lymphomas. However, most epigenetic studies in hematologic neoplasms (HNs) have focused either on the analysis of few candidate genes or many genes and few HN entities,
Agirre, Xabier, Alvarez, Sara, Ammerpohl, Ole, Bibikova, Marina, Brüggemann, Monika, Bug, Stefanie, Calasanz, Maria J., Cruz Cigudosa, Juan, Deckert, Martina, Dreyling, Martin, Du, Ming Q., Dyer, Martin J. S., Dürig, Jan, Fan, Jian-Bing, Gesk, Stefan, Haferlach, Claudia, Hansmann, Martin-Leo, Harder, Lana, Hartmann, Sylvia, Klapper, Wolfram, Küppers, Ralf, Martin-Subero, Jose Ignacio, Montesinos-Rongen, Manuel, Nagel, Inga, Pott, Christiane, Prosper, Felipe, Richter, Julia, Román-Gómez, José, Seifert, Marc, Siebert, Reiner, Stein, Harald, Suela, Javier, Trümper, Lorenz, Vater, Inga, Wickham-Garcia, Eliza   +34 more
core  

A digital shadow of CAR T cell expansion in a perfusion bioreactor: Informing optimal harvest times for autologous cell therapy

Biotechnology Progress, EarlyView.
Using online metabolite data from the first few days of a bioreactor run, the digital shadow can forecast the cell concentration in real‐time with an accuracy of 13% (standard deviation ≈ 6%). These predictions can guide the optimal harvest time of CAR T cells for subsequent re‐infusion into the patient.
Joseph R. Egan, Núria Marí‐Buyé, Elia Vallejo Benítez‐Cano, Miquel Costa, Linda Wanika, Michael J. Chappell, Ursula Schultz, Jelena Ochs, Manuel Effenberger, David Horna, Qasim Rafiq, Stephen Goldrick   +11 more
wiley   +1 more source

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

Cancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai, Tao Fan, Chu Xiao, Ziqin Deng, Yixiao Liu, Chunxiang Li, Jie He   +6 more
wiley   +1 more source

NAT10 regulates tumor progression and immune microenvironment in pancreatic ductal adenocarcinoma via the N4‐acetylated LAMB3‐mediated FAK/ERK pathway

Cancer Communications, EarlyView.
Abstract Background N‐acetyltransferase 10 (NAT10) was reported to be associated with the immune microenvironment in several cancers. However, it is not known in pancreatic ductal adenocarcinoma (PDAC). This study aimed to elucidate the roles and mechanisms of NAT10 in tumor malignancy and the tumor microenvironment (TME) in PDAC.
Enhong Chen, Qin Wang, Leisheng Wang, Zebo Huang, Dongjie Yang, Changyong Zhao, Wuqiang Chen, Shuo Zhang, Shuming Xiong, Youzhao He, Yong Mao, Hao Hu   +11 more
wiley   +1 more source

Subcutaneous Panniculitis-like T-cell Lymphoma

Clinical Dermatology Review
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a primary, rare cutaneous T-cell lymphoma that resembles panniculitis and accounts for
Sonal Mandli, Rutu Harsh Oza, Amita H Sutaria, Bela J Shah   +3 more
doaj   +1 more source

Canine lymphoma: a retrospective study (2009-2010) [PDF]

, 2012
This study reviews the medical records of 56 dogs diagnosed with lymphoma based on the cytological and/or histological results between January 1, 2009 and December 31, 2010.
Daminet, Sylvie, Mortier, Femke, Van de Maele, Isabel, Vandenabeele, Sophie   +3 more
core   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Follicular T-cell lymphoma: A rare entity

Hematology Reports, 2020
Follicular T-cell lymphoma: A rare entity Background: Follicular T-cell lymphoma (FTCL) is a recently described variant of peripheral T-cell lymphoma, NOS in the World Health Organization (WHO) classifications of lymphoid neoplasms. It is a rare neoplasm
O.T. Eryilmaz, N. Dogruyol, A. Ozagari, F. Kabukcuoglu   +3 more
doaj  

Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial

The Lancet, 2019
S. Horwitz, O. O’Connor, B. Pro, T. Illidge, M. Fanale, R. Advani, N. Bartlett, J. H. Christensen, F. Morschhauser, E. Domingo-Domènech, G. Rossi, W. Kim, T. Feldman, A. Lennard, D. Belada, Á. Illés, K. Tobinai, K. Tsukasaki, S. Yeh, A. Shustov, A. Hüttmann, K. Savage, S. Yuen, S. Iyer, P. Zinzani, Zhaowei Hua, M. Little, Shangbang Rao, J. Woolery, T. Manley, L. Trümper, D. Aboulafia, O. Alpdogan, K. Ando, L. Arcaini, L. Baldini, Naresh Bellam, N. Bartlett, D. B. Yehuda, F. Benedetti, Peter Borchman, D. Bordessoule, P. Brice, J. Briones, D. Caballero, A. Carella, Hung Chang, June Weon Cheong, Seok-Goo Cho, I. Choi, S. Choquet, A. Colita, Angela Giovanna Congui, F. d'Amore, N. Dang, K. Davison, S. Guibert, P. Brown, V. Delwail, J. Demeter, F. Raimondo, Y. Do, E. Domingo, Michael G. Douvas, M. Dreyling, T. Ernst, K. Fay, S. Ferrero, I. Flinn, A. Forero-Torres, C. Fox, J. Friedberg, N. Fukuhara, J. García-Marco, Jorge Gayoso Cruz, J. Codina, R. Gressin, A. Grigg, R. Gurion, C. Haioun, R. Hájek, M. Hanel, K. Hatake, Rob Hensen, N. Horowitz, A. Huttmann, Á. Illés, K. Ishizawa, M. Islas‐Ohlmayer, E. Jacobsen, M. Janakiram, W. Jurczak, M. Kaminski, Koji Kato, I. Kirgner, C. Kuo, M. Lazaroiu, K. Du, Jong-Seok Lee, S. Legouill, P. LaRosée, I. Levi, B. Link, H. Maisonneuve, D. Maruyama, J. Mayer, J. McCarty, P. McKay, Y. Minami, H. Mociková, E. Morra, J. Muñoz, H. Nagai, O. O'connor, Stephen Samuel Opat, R. Pettengell, A. Pezzutto, M. Pfreundschuh, A. Pluta, P. Porcu, H. Quach, A. Rambaldi, William E. P. Renwick, Ruben Reyes, A. Izquierdo, J. Ruan, C. Rusconi, G. Salles, A. Santoro, J. Sarriera, K. Savage, H. Shibayama, C. Suh, A. Sureda, M. Tanimoto, M. Taniwaki, H. Tilly, M. Trněný, L. Trumper, N. Tsukamoto, U. Vitolo, J. Walewski, E. Weidmann, M. Wilhelm, M. Witzens‐Harig, A. Yacoub, Kazuhito Yamamoto, S. Yoon, H. Yun, J. Zain   +149 more
semanticscholar   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source