Results 191 to 200 of about 465,548 (350)

Tumor Organoids: Breakthroughs in Clinical Decision Making, Drug Development, and Translational Advances Beyond Conventional Models

open access: yesMed Research, EarlyView.
ABSTRACT Tumor organoid models are revolutionizing cancer research by bridging the translational gap between conventional two‐dimensional cell cultures and animal models. This Editorial thoroughly explores the fundamental innovations of patient‐derived organoid technology.
Yimao Wu   +4 more
wiley   +1 more source

Belinostat for the treatment of relapsed or refractory peripheral T-cell lymphoma

open access: yesJournal of Oncology Pharmacy Practice, 2017
P. Campbell, Christan Thomas
semanticscholar   +1 more source

Hidden Insights: Comprehensive Radiological Analysis of Four Skeletal Populations From 13th–19th Century Southern Finland Reveals Neoplastic and Other Lesions Invisible on Bone Surfaces

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT This study aims to identify lesions confined to the internal structures of bones. A radiographic analysis was performed on 219 archaeological, historical period skeletons from southern Finland. Although the study examines nearly all preserved skeletal elements using plain radiographs, it does not incorporate computed tomography.
Kati Salo   +2 more
wiley   +1 more source

The Evolution of Pneumocystis jirovecii Pneumonia Prophylaxis for Pediatric Patients With Extracranial Solid Tumors: A Review of Historical Insights and Future Directions

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pneumocystis jirovecii pneumonia (PJP) remains a modern‐day complication for pediatric patients receiving treatment for extracranial solid tumors (ST), highlighting the need for reconsideration of our current approach toward PJP prophylaxis. This critical review aims to evaluate both universal and risk‐stratified approaches to PJP prophylaxis ...
Kriti Kumar   +8 more
wiley   +1 more source

ENO1 inhibition synergizes with chidamide to induce ferroptosis in PTCL-NOS through metabolic remodeling. [PDF]

open access: yesBlood Sci
Zhu F   +12 more
europepmc   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto   +2 more
wiley   +1 more source

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre   +5 more
wiley   +1 more source

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