Results 111 to 120 of about 492,557 (263)

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

Risk and Survival Outcomes of Secondary Primary Malignancies in Chinese Lymphoma Patients in the Era of Modern Targeted Therapies: A Single-Center Retrospective Cohort Study

Blood and Lymphatic Cancer: Targets and Therapy
Chen Qiu,1,2,* Tingting Zhang,1,2,* Xuejing Yang,3,* Yafang Guo,4 Zihui Gong,5 Dong Song1,21Department of Lymphoma, Shanxi Bethune Hospital (Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi ...
Qiu C, Zhang T, Yang X, Guo Y, Gong Z, Song D   +5 more
doaj  

PB2662: ABO BLOOD GROUP TYPE AND RISK OF VENOUS THROMBOEMBOLISM IN PATIENTS WITH LYMPHOMA

HemaSphere, 2023
Vladimir Otasevic, Jelena Ivanović, Vojin Vukovic, Sofija Sarac, Biljana Mihaljevic, Darko Antic   +5 more
doaj   +1 more source

Sjögren's Disease-Associated Parotid MALT Lymphoma: Diagnostic Pitfall of Ultrasound-Guided Core Needle Biopsy. [PDF]

Diagnostics (Basel)
Chen SY, Hung WC, Cheng PC, Lo WC, Chang CM, Wen MH, Chen AW, Liao LJ.   +7 more
europepmc   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

A Multi‐Targeting Chimeric Antigen Receptor‐T Cell Platform to Overcome Antigen Heterogeneity in the Treatment of Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A dual‐transmembrane Bicephali CAR‐T platform simultaneously targets CD276 and NKG2D ligands to address antigen heterogeneity in non‐small cell lung cancer. By improving immune synapse formation, mitochondrial fitness, antioxidant capacity, and stem‐like persistence, this design enhances durable tumor control and provides a versatile strategy to ...
Lina Wang, Yanlei Zhang, Shuixiu Peng, Chenchen Hou, Huaqi Guo, Tianyu Zhou, Alex H. Chang, Lifeng Yan, Weining Xiong   +8 more
wiley   +1 more source

A prospective study of prophylactic dexamethasone with glofitamab in relapsed/refractory large B-cell lymphoma

Blood Neoplasia
J. Erika Haydu, Matthew M. Lei, Robert A. Redd, Jeffrey A. Barnes, Elijah P. Darnell, Ephraim P. Hochberg, P. Connor Johnson, Ronald W. Takvorian, James I. Weitzman, Elliot C. Woods, Tiffany L. Hurvitz, Courtney D. Lafranchi, Patricia Livingstone, Julia M. Lynch, Emily N. Patterson, Jack E. Malespini, Brianne M. McGree, Alexa O. Santilli, Katherine A. Thorp, Maryanne M. Sherburne, Lindsey B. Wardrop, Uvette Y. Lou, Mark N. Sorial, Catherine Cho, Josie Ford, Ronnie Nemac, Jacob D. Soumerai, Jeremy S. Abramson   +27 more
doaj   +1 more source

Unilateral Orbital Lymphomas: A Structured Multidisciplinary Workflow for Diagnosis and Management. [PDF]

Clin Ophthalmol
Romeo MA, Gaeta A, Giannaccare G, Ferraro S, Ottonelli G, Manara S, Giannitto C, Lucia AMA, Carnevali A, Di Maria A.   +9 more
europepmc   +1 more source

Mitochondrial Localization of Cx26 Promotes Colorectal Cancer Malignancy and Exposes a Fatal Vulnerability to Drug Targeting

Advanced Science, EarlyView.
Mitochondrial localization of Cx26 emerges as a double‐edged sword in colorectal cancer. PIMT‐mediated methylation of Cx26 promotes its mitochondrial localization and stability. Mitochondrial Cx26 then facilitates ER‐mitochondria communication and Ca2+ signaling, thereby promoting metastatic progression. Bortezomib exploits this malignant adaptation by
Jie Wang, Lu Chen, Jia Qin, Xiaoning Wang, Sunlan Ye, Ning An, Mei Bai, Yan Shen, Xuefeng Wu, Qiang Xu   +9 more
wiley   +1 more source