Results 201 to 210 of about 879,101 (311)

Hepatotoxicity of Nonesterified Fatty Acids to Dairy Cows: Pathophysiological Mechanisms and Prospective Solutions

open access: yesAnimal Research and One Health, EarlyView.
Unregulated inflammation increases non‐esterified fatty acids (NEFAs), and triggers multi‐pathway hepatocyte damage including oxidative stress, mitochondrial dysfunction, and metabolic disorders in dairy cows. ABSTRACT Circulating concentrations of nonesterified fatty acids (NEFAs) are elevated due to lipid mobilization from adipose tissue in ...
Siqing Mao   +12 more
wiley   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

open access: yesArthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Single‐Cell Level Characterization of B Cell Depletion and Repopulation Following Rituximab in Systemic Lupus Erythematosus

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang   +9 more
wiley   +1 more source

Treatment and outcomes of pulmonary mucosa-associated lymphoid tissue lymphoma: A multicenter analysis of 186 patients. [PDF]

open access: yesCancer
Suzuki K   +21 more
europepmc   +1 more source

Small Business Grants Awarded by the National Institutes of Health for Rhinologic Diseases, 1985–2024

open access: yes
International Forum of Allergy &Rhinology, EarlyView.
Jack Birkenbeuel   +7 more
wiley   +1 more source

Acromial Osteotomy for Dynamic Posterior Shoulder Instability

open access: yesArthroscopy Techniques, EarlyView.
Abstract Posterior shoulder instability is less prevalent than anterior instability but shows a rising incidence, particularly among young and active individuals. Diagnosis is often challenging due to nonspecific symptoms, leading to delays and underestimation of prevalence. Its etiology is multifactorial, including traumatic events, iatrogenic causes,
Ricardo Mendes   +6 more
wiley   +1 more source

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