Results 151 to 160 of about 60,295 (253)

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Acquired Immunodeficiency in Newborn Following Intrauterine Exposure to Thiopurines for Treatment of Inflammatory Bowel Disease. [PDF]

ACG Case Rep J
Morand S, Lam MT, Amornsawadwattana S, Gutierrez A, Nguyen AA, Prockop S, Ruggiero J, Kitcharoensakkul M.   +7 more
europepmc   +1 more source

JAK Inhibition in PNPT1‐Related Mitochondrial Interferonopathy: A Case Report and Review of Mitochondrial–Immune Crosstalk

JIMD Reports, Volume 67, Issue 4, July 2026.
ABSTRACT Biallelic pathogenic variants in PNPT1 cause combined oxidative phosphorylation deficiency 13 (COXPD13) (MIM #614932), linking mitochondrial dysfunction to type I interferon (IFN) activation through cytosolic leakage of mitochondrial double‐stranded RNA (mt‐dsRNA).
Dan Ross Brooks, Hyun Yong Koh, Taylor Martin Kerrins, Steven Lang, Emily Bland, Rui Yang, Sarah Kogan Nicholas, Stephanie Jean Sikkink, Stephen Kralik, Christine Eng, Chaya Nautiyal Murali, Seema Lalani, Pilar Lenglet Magoulas, Lisa Emrick, Kristen Sydney Fisher, Fernando Scaglia   +15 more
wiley   +1 more source

Clinical Characteristics and Determinants of Complications in Pediatric Herpes Zoster Requiring Hospitalization. [PDF]

Children (Basel)
Bilașco A, Drăgănescu AC, Miron VD, Rădulescu CR, Băncilă DM, Tudor AM, Vișan AC, Pleșca DA.   +7 more
europepmc   +1 more source

An Explainable Machine Learning Model for Early Prediction of Incident Myocardial Injury in Patients With Severe Fever With Thrombocytopenia Syndrome

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT This study aimed to develop an explainable machine learning–based model to enable early prediction of incident myocardial injury during hospitalization among patients with severe fever with thrombocytopenia syndrome (SFTS). This multicenter retrospective cohort study included and analyzed clinical data from 1,088 patients with SFTS who were ...
Xiang Li, Xiaotong Yu, Wei Zhou, Sujuan Zhang, Zibo Fan, Yuanni Liu, Yi Shen, Zhenghua Zhao, Jianping Duan, Ling Lin, Zhihai Chen, Wei Zhang   +11 more
wiley   +1 more source

Neutrophil-to-lymphocyte ratio as a practical alternative to mHLA-DR measurement in delayed sepsis-induced immunosuppression. [PDF]

Intensive Care Med
Lafon T, Venet F, Lukaszewicz AC, Monneret G.   +3 more
europepmc   +1 more source

Torque Teno Virus Dynamics in Plasma and BAL of COVID‐19 ARDS Patients With and Without ECMO

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT Extracorporeal membrane oxygenation (ECMO) is used to manage severe acute respiratory distress syndrome (ARDS) and is associated with immune modulation. Torque teno virus (TTV) has been proposed as a surrogate marker of immune competence, but it remains unclear whether ECMO influences TTV levels.
Armin Marcus Bumberger, Marie‐Theres Kastner, Riem Gawish, Lina Rüsing, Iwan Wukits, Monika Breuer, Robert Strassl, Christoph Steininger, Oliver Robak   +8 more
wiley   +1 more source

Predictors of acute lymphopenia after radiotherapy for prostate cancer including pelvic node irradiation: results of a real-world prospective multi-centric study. [PDF]

ESMO Real World Data Digit Oncol
Vavassori V, Pavarini M, Alborghetti L, Aimonetto S, Maggio A, Landoni V, Ferrari P, Bianculli A, Petrucci E, Cicchetti A, Farina B, Ubeira-Gabellini MG, Salmoiraghi P, Moretti E, Avuzzi B, Giandini T, Munoz F, Magli A, Noris Chiorda B, Sanguineti G, Waskiewicz JM, Rago L, Cante D, Girelli G, Villa E, Di Muzio NG, Rancati T, Fiorino C, Cozzarini C.   +28 more
europepmc   +1 more source

Lymphopenia and autoimmune diseases.

Arthritis research & therapy, 2004
openaire   +2 more sources

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source