Objective Calcinosis cutis (CC) is dystrophic calcification affecting 20% to 40% of patients with juvenile dermatomyositis (JDM). Management of CC is often challenging owing to its being refractory to usual therapeutic options. Type I interferon (IFN)‐mediated immune dysregulation may be involved in the pathogenic role in CC, suggesting that altering ...
Pragati Jain +11 more
wiley +1 more source
Acquired Immunodeficiency in Newborn Following Intrauterine Exposure to Thiopurines for Treatment of Inflammatory Bowel Disease. [PDF]
Morand S +7 more
europepmc +1 more source
This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji +2 more
wiley +1 more source
Clinical Characteristics and Determinants of Complications in Pediatric Herpes Zoster Requiring Hospitalization. [PDF]
Bilașco A +7 more
europepmc +1 more source
Abstract Purpose Ischemic stroke poses a major global health burden, and growing evidence points to the microbiota–gut–brain axis as an important contributor to stroke pathophysiology and recovery. The purpose of this review is to summarize current knowledge on bidirectional gut‐brain communication in stroke, establishing gut dysbiosis as an upstream ...
Ruihui Weng +3 more
wiley +1 more source
Neutrophil-to-lymphocyte ratio as a practical alternative to mHLA-DR measurement in delayed sepsis-induced immunosuppression. [PDF]
Lafon T +3 more
europepmc +1 more source
This graphical abstract illustrates how acute ischemic stroke may be accompanied by neuroendocrine‐immune dysregulation, represented by a low FT3/FT4 ratio and a high neutrophil‐to‐lymphocyte ratio, which together improve early identification of patients at risk for post‐ischemic stroke urinary tract infection.
Zhangyan Geng +8 more
wiley +1 more source
Predictors of acute lymphopenia after radiotherapy for prostate cancer including pelvic node irradiation: results of a real-world prospective multi-centric study. [PDF]
Vavassori V +28 more
europepmc +1 more source
Microbiota–Neuroinflammation Crosstalk in Primary Brain Tumors: Focus on Glioblastoma
Microbiota–neuroinflammation crosstalk in GBM. The schematic summarizes how gut microbiota and microbiota‐derived signals may influence GBM biology through gut–brain signaling, microbial metabolites, systemic immune modulation, BBB‐related pathways, tumor‐associated microbial signals, and immune‐metabolic changes within the GBM microenvironment.
Tareq Nayef AlRamadneh +8 more
wiley +1 more source
Ruxolitinib-Treated Myeloproliferative Neoplasms: Real-World Infectious Outcomes and Preventive Practices from a Single Center. [PDF]
Aydin MS +6 more
europepmc +1 more source

