Results 161 to 170 of about 88,412 (297)

Confined B‐Cell Reconstruction and High T‐Cell Clonality Define Clinical Response to Cladribine Treatment

open access: yesAnnals of Neurology, Volume 99, Issue 5, Page 1166-1172, May 2026.
Cladribine tablets are approved for relapsing multiple sclerosis, mediating their clinical effect by moderately depleting lymphocytes. In a prospective, monocentric study including 22 patients completing 2 annual cycles of cladribine, B‐ and T‐cell receptor repertoires and relapse activity were assessed at baseline and after 24 months. T‐cell clonality
Tilman Schneider‐Hohendorf   +8 more
wiley   +1 more source

Mecapegfilgrastim for Prophylaxis of Immunochemotherapy‐Induced Neutropenia in Patients With Diffuse Large B‐Cell Lymphoma: A Multicenter Pilot Trial

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background This study evaluated the efficacy and safety of mecapegfilgrastim for preventing immunochemotherapy‐induced neutropenia in treatment‐naive patients with diffuse large B‐cell lymphoma (DLBCL). Methods In this open‐label, multicenter exploratory trial, patients were randomized in a 2:1 ratio to receive mecapegfilgrastim or no ...
Jie Wang   +15 more
wiley   +1 more source

Manifestaciones hematológicas, etiopatogenia y exámenes de laboratorio en la enfermedad por virus Ébola

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia
La enfermedad por el virus del Ébola es una dolencia con frecuencia fatal, causada por una de las cinco cepas altamente contagiosas de este virus que afecta, tanto a animales como a seres humanos, cuya tasa de letalidad puede llegar al 90 %.
Juan Carlos Jaime Fagundo   +3 more
doaj  

Maintenance therapy for metastatic non-squamous non-small cell lung cancer: efficacy and biomarker analysis of pemetrexed discontinuation. [PDF]

open access: yesTransl Lung Cancer Res
Lin Y   +13 more
europepmc   +1 more source

Fruquintinib Plus TAS‐102 With or Without SBRT as Third‐ Or Later‐Line Therapy for Metastatic Colorectal Cancer: Preliminary Results From a Prospective Phase II Trial

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Both fruquintinib and TAS‐102 monotherapies are guideline‐recommended for third‐line treatment of metastatic colorectal cancer (mCRC). This study aimed to analyze the preliminary outcomes of fruquintinib combined with TAS‐102, with or without stereotactic body radiation therapy (SBRT), as a third‐ or later‐line therapy for mCRC.
Yi Wang   +19 more
wiley   +1 more source

From Screening to Delivery of Disease‐Modifying Therapy: Real World Follow‐Up of Children With Early‐Stage Type 1 Diabetes

open access: yes
Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5379-5383, June 2026.
Theodora Papanikolaou   +5 more
wiley   +1 more source

Neoadjuvant Immunochemotherapy Increases the Abundance of Tertiary Lymphoid Structures and Lymphocyte Subpopulations Is Associated With Prognosis of Esophageal Squamous Cell Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Neoadjuvant immunochemotherapy (NIC) has emerged as a promising strategy for esophageal squamous cell carcinoma (ESCC). However, its impact on tertiary lymphoid structures (TLSs) and the immune microenvironment remains to be fully elucidated. We retrospectively analyzed 50 ESCC patients treated with NIC (n = 25) or chemotherapy alone (n = 25 ...
Ning Li   +7 more
wiley   +1 more source

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