Results 191 to 200 of about 60,678 (260)

Efficacy and Safety of Daratumumab‐Based Regimens in Multiple Myeloma: A Systematic Review and Meta‐Analysis of Phase III Randomized Controlled Trials

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Introduction Multiple myeloma is a malignant plasma cell disorder predominantly affecting older adults and poses a significant health burden due to its incurable nature, high relapse rate, and associated immune dysfunction. Daratumumab, when added to standard therapy, has shown promising results in large trials.
Abdul Moiz Khan, Hafsa Ajmal, Muddassir Khalid, Waleed Babar, Usama Shafaqat, Tooba Fida, Mohammad Aitzaz Hassan, Sibgha Fatima, Ahmad Sameed Akram, Fred Segawa   +9 more
wiley   +1 more source

Lymphopenia in Bacterial Sepsis and SARS-CoV-2 Infection. [PDF]

Biomedicines
Terteşş R, Petcu LC, Niţu BF, Mavrodin MM, Cucli E, Topa EA, Ionescu C, Cârciumaru N, Cambrea SC.   +8 more
europepmc   +1 more source

Dynamic Prognostic Nutritional Index With Circulating Tumor DNA Predicts Survival in Localized Pancreatic Ductal Adenocarcinoma

Journal of Surgical Oncology, Volume 134, Issue 2, Page 272-281, August 2026.
ABSTRACT Background and Objectives To evaluate the prognostic significance of baseline and longitudinal changes in prognostic nutritional index (PNI) in localized pancreatic ductal adenocarcinoma (PDAC) and to assess the complementary prognostic value of PNI with tumor burden measured by circulating tumor DNA (ctDNA).
Alex Horowitz, Claire Shen, Dominic J. Vitello, Madison Cox, Amy Wells, Krishay Sridalla, David J. Bentrem, Qiang Zhang, Ishan Roy, Akhil Chawla   +9 more
wiley   +1 more source

Managing non-SCID T cell lymphopenia after TREC-based newborn screening. [PDF]

J Hum Immun
Duintjer AJ, Bredius RGM, van den Berg JM, van de Corput L, Dik WA, van Gijn ME, Henriet SS, Kemper EA, Kuijpers TW, Legger GE, van Montfrans JM, Schölvinck LH, Vermont CL, Voorhoeve E, Weijman G, van Well GTJ, Zonneveld-Huijssoon E, van der Burg M, Blom M.   +18 more
europepmc   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Visceral leishmaniasis in a multiple sclerosis patient: a rare complication of fingolimod-induced lymphopenia. [PDF]

Rev Esp Quimioter
García-Alabarce A, Cornejo-Calvo E, de Salazar-González A, Guirao-Arrabal E.   +3 more
europepmc   +1 more source

Lymphatic Endothelial Cells in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang, Wang Lin, Hengyang Liu, Jixin Zhong, Shiliang Li, Xiaoquan Rao   +5 more
wiley   +1 more source

Immune Dysregulation in Branched Chain Organic Acidemias. [PDF]

J Inherit Metab Dis
Shakerdi AL, Drda J, Dutta JA, Vockley J.   +3 more
europepmc   +1 more source

No association between temozolomide maintenance and survival after first‐line treatment in primary CNS lymphoma

HemaSphere, Volume 10, Issue 8, August 2026.
Nashif Chowdhury, Jenni Niemi, Haris Babačić, Hanna‐Maija Rantakylö, Ingrid Glimelius, Mats Jerkeman, Mats Hellström   +6 more
wiley   +1 more source

Clinical outcome, imaging and histopathological findings of liver cirrhosis in dogs

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract Cirrhosis is a severe and irreversible condition resulting from chronic liver injury, characterised by extensive fibrosis and regenerative nodules. This report describes three dogs with cirrhosis. The main clinical findings included ascites, reduced body condition score and inappetence. Anaemia, thrombocytopenia, hypoalbuminaemia, and elevated
Wanderson Feliciano Duarte da Silva, Roger Fernando Neves da Silva, Edson Moleta Colodel, Pedro Eduardo Brandini Nespóli, Valeria Regia Franco Sousa   +4 more
wiley   +1 more source