Results 181 to 190 of about 60,295 (253)

Clinical Considerations of Splenic Dose Constraints to Mitigate Radiation-Induced Lymphopenia. [PDF]

Cancer Med
Ma Y, Zhang S, Ma J, Gao A, Liu J, Ma H, Zhou Q, Qian J, Zhang L.   +8 more
europepmc   +1 more source

Insights Into the Susceptibility of Fungal Infection and STAT3 Genetic Mutations

Mycoses, Volume 69, Issue 7, July 2026.
ABSTRACT Signal transducer and activator of transcription 3 (STAT3) is a key transcription factor that regulates a spectrum of genes and signalling pathways critical for the antifungal immune response. Mutations in the STAT3 gene confer susceptibility to severe and recurrent fungal infections, predominantly via disruption of interleukin‐17 (IL‐17 ...
Fengming Li, Xiaodong Liu, Yuanyuan Li, Jie Wu, Ningning Dang, Jing Guo   +5 more
wiley   +1 more source

Visceral leishmaniasis in a multiple sclerosis patient: a rare complication of fingolimod-induced lymphopenia. [PDF]

Rev Esp Quimioter
García-Alabarce A, Cornejo-Calvo E, de Salazar-González A, Guirao-Arrabal E.   +3 more
europepmc   +1 more source

Optimizing TREC‐ and KREC‐based newborn screening: Risk‐stratified algorithms significantly reduce referrals

Pediatric Allergy and Immunology, Volume 37, Issue 7, July 2026.
Abstract Background Newborn screening (NBS) quantifying T‐cell receptor excision circles with or without kappa‐deleting recombination excision circles (TREC, KREC) enables early detection of severe T‐ and/or B‐cell lymphopenia. However, both markers have limited specificity, often resulting in unnecessary referrals.
Maarja Soomann, Seraina Prader, Susanna Sluka, Jana Pachlopnik Schmid, Johannes Trück   +4 more
wiley   +1 more source

Managing non-SCID T cell lymphopenia after TREC-based newborn screening. [PDF]

J Hum Immun
Duintjer AJ, Bredius RGM, van den Berg JM, van de Corput L, Dik WA, van Gijn ME, Henriet SS, Kemper EA, Kuijpers TW, Legger GE, van Montfrans JM, Schölvinck LH, Vermont CL, Voorhoeve E, Weijman G, van Well GTJ, Zonneveld-Huijssoon E, van der Burg M, Blom M.   +18 more
europepmc   +1 more source

Transient B cell lymphopenia revealed by KRECs newborn screening: Post‐screening referral strategies, clinical course, and follow‐up

Pediatric Allergy and Immunology, Volume 37, Issue 7, July 2026.
Abstract Background Newborn screening (NBS) for inborn errors of immunity increasingly uses T‐cell receptor excision circles (TREC) and, in some programs, Kappa‐deleting recombination excision circles (KREC) to detect early T‐ and B‐cell lymphopenia. While TREC‐based screening is well established, the significance and management of isolated low KREC ...
Guarnieri Valentina, Drago Enrico, Pelosi Caterina, Boscia Silvia, Schena Francesca, Traverso Monica, Aloi Concetta, Salina Alessandro, Palmeri Serena, Cassanello Michela, Maghnie Mohamad, Astorino Valeria, Lodi Lorenzo, Azzari Chiara, Volpi Stefano, Ricci Silvia   +15 more
wiley   +1 more source

Cytomegalovirus Reactivation During Therapy for Pediatric Acute Lymphoblastic Leukemia. [PDF]

J Med Virol
Melavarige Venkatagiri A, Reddy N, Chandwani R, Shekar N, Perampalli Manjunath S, Abdu Rahiman E, Mukhopadhyay C, Bhat Kalya V.   +7 more
europepmc   +1 more source

Extranodal natural killer/T‐cell lymphoma: From fatal to curable

CA: A Cancer Journal for Clinicians, Volume 76, Issue 4, July/August 2026.
Abstract Extranodal natural killer (NK)/T‐cell lymphoma (ENKTCL) is one of the most aggressive non‐Hodgkin lymphomas characterized by NK‐cell or T‐cell origins, a geographic prevalence in Asian and South American populations, and Epstein–Barr virus (EBV) infection.
Jie Xiong, Yok‐Lam Kwong, Laurence de Leval, Shu‐Nan Qi, Choon Kiat Ong, Philippe Gaulard, Arnaud Jaccard, Steven M. Horwitz, Ye‐Xiong Li, Sai‐Juan Chen, Ritsuro Suzuki, Won Seog Kim, Wei‐Li Zhao   +12 more
wiley   +1 more source

Concurrent immunoradiotherapy with Toripalimab versus concurrent chemoradiotherapy with S-1 in older patients with esophageal squamous cell carcinoma: a retrospective cohort study. [PDF]

Transl Oncol
Huang Y, Zhou C, Zhu J, Jia H, Zhao F, Yang H, Zhou S.   +6 more
europepmc   +1 more source

Inflammatory Stewardship—A Perspective for Active Management of Acute Inflammation

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Inflammatory stewardship frames inflammation as a manageable clinical domain requiring explicit strategy, governance, and feedback. It aligns diagnostics, risk stratification, biomarker interpretation, and immunomodulatory decisions across perioperative and critical‐care teams.
Lennart Finn Herrlich, Hubert Schrezenmeier, David Alexander Christian Messerer   +2 more
wiley   +1 more source