Results 61 to 70 of about 1,266,459 (215)

The association between inborn errors of immunity and Hodgkin lymphoma—A register‐based case–control study in Sweden

British Journal of Haematology, EarlyView.
Summary Immune dysfunction is implicated in the aetiology of Hodgkin lymphoma (HL), but the association between inborn errors of immunity (IEI) and HL remains poorly understood. We conducted a retrospective, register‐based case–control study in Sweden over five decades to investigate the relationship between IEI and HL. Individuals diagnosed with HL in
Agnes Winsa, Ingemar Lagerlöf, Fredrik Ellin, Mats Fredriksson, Åsa Nilsdotter‐Augustinsson, Marcus Bendtsen, Jörg Cammenga, Sofia Nyström   +7 more
wiley   +1 more source

Long‐term results of brentuximab vedotin and bendamustine for first‐line treatment of Hodgkin lymphoma in the elderly (HALO trial)

British Journal of Haematology, EarlyView.
Summary The Hodgkin lymphoma treatment in the elderly (eHL) is a challenge due to a narrow therapeutic window between therapy effectiveness and toxicity. Both bendamustine (Be) and brentuximab vedotin (BV) are well‐tolerated, effective drugs in relapsing HL, but no data exist on Be‐BV frontline treatment in eHL.
Andrea Gallamini, Simonetta Viviani, Davide Rapezzi, Caterina Patti, Pierre Feugier, Alessandro Rambaldi, Fontanet Bijou, Anna Borra, Cécile Borel, Tanguy Pace‐Loscos, Renaud Schiappa, Stephane Chauvie, Colin Debaigt, Anna Guidetti, Olivier Humbert, Jean‐Marc Schiano De Colella   +15 more
wiley   +1 more source

Posttransplant lymphoproliferative disorders following liver transplantation: Where are we now?

, 2015
Liver transplantation has emerged as a life-saving treatment for several patients with acute liver failure, end stage liver disease and primary hepatic malignancies.
Cardinaels, Nina, Dierickx, Daan
core   +1 more source

Immunodeficiency-Associated Epstein-Barr Virus-Positive B-cell Lymphoproliferative Disorders

, 2023
Sources of immune deficiency and dysregulation (IDD) are being increasingly recognized and defined, as are IDD-related B-cell lymphoproliferative lesions and lymphomas occurring in these patients. In this review, basic biology of Epstein-Barr virus (EBV)
Jennifer Chapman, Chapman, Jennifer
core   +1 more source

Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy

Cancer Science, EarlyView.
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang, Changyi Fan, Shiheng Chen, Tianyue Lu, Yuanyuan Li, Feng Du, Shanshan Wang   +6 more
wiley   +1 more source

Real‐World Safety and Efficacy of Pola‐R‐CHP in Previously Untreated DLBCL: POLASTAR Interim Analysis of 500 Patients

Cancer Science, EarlyView.
In this analysis of a diverse cohort of 500 patients with previously untreated DLBCL in a real‐world clinical setting, Pola‐R‐CHP demonstrated high response rates at end‐of‐treatment, which were consistent among the overall population, in patients > 80 years and regardless of International Prognostic Index status and cell of origin subtypes.
Takahiro Kumode, Hitomi Sawa, Kohta Miyawaki, Atsushi Satake, Nobuhiro Kanemura, Ritsuro Suzuki, Yuki Fujiwara, Yasuhiro Nagate, Shuichi Ota, Takahiro Fujino, Hideki Goto, Noriko Fukuhara, Mamiko Sakata‐Yanagimoto, Koji Izutsu, Momoko Nishikori, Hirohiko Shibayama, Daisuke Ennishi, Takayuki Shimose, Mai Asai, Itaru Matsumura, Koichi Akashi, Koji Kato   +21 more
wiley   +1 more source

Recurrent EBV-negative monomorphic post-transplant lymphoproliferative disorder confined to sequential liver allografts

Transplantation Reports
Post-transplant lymphoproliferative disorder (PTLD) is a heterogeneous spectrum of lymphoproliferative disorders that can develop in the setting of immunosuppression following transplant.
Taylor Viggiano, Amani Elshaer, Hally Chaffin, Bashar Aqel, Michele Barnhill   +4 more
doaj   +1 more source

Occult hepatitis C virus infection in patients with malignant lymphoproliferative disorders

International Journal of Immunopathology and Pharmacology, 2020
Despite the link between HCV and malignant lymphoproliferative disorders has been established, the association between occult hepatitis C virus infection and malignant lymphoproliferative disorders remains obscure.
Abeya A Lotfi, Asmaa E Mohamed, Nahela A Shalaby, Deena S Eissa, Ehab El-Dabaa, Ayman M Sallam, Mahmoud M Kamel, Hisham Abdelaziz, Amal M El-Afifi, Ahmed S Abdel-Moneim   +9 more
doaj   +1 more source

Primary Cutaneous Gamma‐Delta T‐Cell Lymphoma Complicating Long‐Standing Immunosuppressed Dermatomyositis

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Primary cutaneous gamma‐delta T‐cell lymphoma (PCGD‐TCL) is a rare cytotoxic lymphoma with key oncogenic drivers in the JAK/STAT pathway. Also primarily involving the subcutaneous adipose tissue, subcutaneous panniculitis‐like T‐cell lymphoma (SPTCL) is more frequently encountered in scenarios of autoimmune disorders.
Bennett Christie‐Nguyen, Youn H. Kim, David F. Fiorentino, Danielle Tartar, Ryanne Brown, Robert A. Novoa, Kerri E. Rieger   +6 more
wiley   +1 more source

An Uncommon Case of Eosinophilic Myocarditis in a Patient With Autoimmune Lymphoproliferative Syndrome

Annals of Internal Medicine: Clinical Cases
Eosinophilic myocarditis is a rare but well-described inflammatory condition with high morbidity and mortality but is not reported as caused by underlying autoimmune lymphoproliferative disorder.
Maria T. Gamero, Stefanie Marek-Iannucci, Yevgeniy Brailovsky, Andrew Peters, Eugene Storozynsky, Patricia Uber, Indranee Rajapreyar   +6 more
doaj   +1 more source