Results 121 to 130 of about 67,139 (243)

Ambient-Stable mRNA Medicines: Emerging Paradigms in Dry and Solid-State Formulation. [PDF]

Pharmaceuticals (Basel)
El-Tanani M, Rabbani SA, Wali AF, Muhana F, Aljabali AAA, El-Tanani Y, Kumar R.   +6 more
europepmc   +1 more source

Tunable Applicator for Microneedle‐Based Medical Devices

Advanced Materials Technologies, EarlyView.
This paper presents a simple, low‐cost tunable applicator (TAPP) for microneedle array patches that uses a material‐agnostic controlled‐fracture mechanism to ensure reliable skin penetration and uniform array engagement. The scalable, modular design is compatible with injection molding and 3D printing, can be integrated directly into patches, and is ...
Dan Ilyn, Jihyun (Luna) Hwang, Ian A. Coates, Jacob Dobson, Andy H. Hung, Netra U. Kamat, John R. Tumbleston, Maria T. Dulay, Gunilla B. Jacobson, Joseph M. DeSimone   +9 more
wiley   +1 more source

Green approach in saponin extraction from Acanthophyllum caryophyllaceae root based on ultrasonication coupled with solvent extraction method and its lyophilization. [PDF]

Sci Rep
Yavarzadeh S, Jafarizadeh-Malmiri H, Ahmadi O.   +2 more
europepmc   +1 more source

Adhesive Double‐Network Granular Organogel E‐Skin

Advanced Materials Technologies, EarlyView.
We introduce a double‐network granular organogel adhesive for electronic skin, overcoming adhesion and strength trade‐offs. It provides reversible, robust bonding and ionic conductivity, enabling wearable and soft robotic e‐skin. Thanks to the e‐skin adhesive, a soft robotic trunk can recognize touch, temperature, humidity, and acidity.
Antonia Georgopoulou, Benhui Dai, Kadence Shen Yu Chow, Josie Hughes, Esther Amstad   +4 more
wiley   +1 more source

<i>In vitro</i> evaluation of stability and hemostatic efficacy of single-donor lyophilized canine plasma. [PDF]

Front Vet Sci
Cha S, Shin C, Kang C, Jung DI, Cho KW, Bae H, Yu D.   +6 more
europepmc   +1 more source

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage

Advanced Science, EarlyView.
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su, Sisheng Zhang, Lidi Liang, Haiyi Bai, Mei Bai, Hanjun He, Yayu Wang, Huan Liu, Xiangxiu Liang, Yu Sun, Hong Wu   +10 more
wiley   +1 more source

Skim Milk as a Multifunctional Cryoprotectant for Fish Probiotic <i>Enterococcus</i> spp.: Impact on Viability During Lyophilization and Long-Term Storage. [PDF]

Microorganisms
Cruz MGD, Silva AMSD, Prada-Mejia KD, Koolen HHF, Tavares GC, Valladão GMR.   +5 more
europepmc   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Unraveling Lyophilization and Redispersion Effects on Miktoarm Polymer-Based Nanoformulations. [PDF]

Int J Mol Sci
Yousefi Adlsadabad S, Théberge-Julien G, Gutierrez FFP, Medina RB, Mercado XM, Rhéaume É, Tardif JC, Kakkar A.   +7 more
europepmc   +1 more source

Model-based monitoring and control of industrial freeze-drying processes: Effect of batch nonuniformity [PDF]

, 2010
Antonello A. Barresi, Barresi A.A., Daniele L. Marchisio, Davide Fissore, Fissore D., Milton N., Oetjen G.W., Rasetto V., Roberto Pisano, Tang X.C., Tang X.C., Valeria Rasetto   +11 more
core   +1 more source