Results 141 to 150 of about 40,837 (264)

A Cryoprotectant-Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals. [PDF]

Adv Mater
Lee S, Kim S, Chong J, Kim MG, Lim K, Lee NE, Koo J, Kang J, Lee H.   +8 more
europepmc   +1 more source

Biomimetic Hydrogel System Targeting S100A8 Centered Neuroimmune Crosstalk and Hypoxia Induced Neuronal Injury

Advanced Science, EarlyView.
A biomimetic hydrogel (HPC@Gel) was developed for traumatic brain injury repair by combining oxygen‐carrying hemoglobin nanoparticles and anti‐inflammatory carbon quantum dots within a brain‐like matrix. The system alleviated hypoxia, reduced harmful neuroimmune signaling, protected neurons, supported neural regeneration, and improved neurological and ...
Peng Liu, Xiaoyang Wu, Xiaoyin Liu, Yuyan Wang, Shichao Jiang, Kai Wu, Gaowei Li, Jie Ding, Chengheng Wu, Dan Wei, Jing Sun, Hongsong Fan, Liangxue Zhou   +12 more
wiley   +1 more source

Enhancing optical properties and stability of DNA-functionalized carbon nanotubes with cryoprotectant-mediated lyophilization. [PDF]

Carbon N Y
Nadeem A, Kindopp A, Junge E, Rahmani M, Roxbury D.   +4 more
europepmc   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source

Investigating the potential of Ulva rigida extracts as a natural anti-aging agent in cosmetics. [PDF]

Sci Rep
Boonpisuttinant K, Taka T, Praiboon J, Phuangborisut S, Kangkawisut N, Ruksiriwanich W, Chutoprapat R, Chompoo W, Samothai K, Udompong S, Poolpol K.   +10 more
europepmc   +1 more source

Nano‐Confined Radical Anion as An NIR‐II Photothermal Immunogenic Amplifier for In Situ Cancer Vaccination

Advanced Science, EarlyView.
A nano‐confined radical anion acts as a photothermal immunogenic amplifier. Kinetically stabilized nanoparticles couple high near‐infrared‐II (NIR‐II) photothermal efficacy with glutathione (GSH) depletion to boost reactive oxygen species (ROS) and immunogenic cell death (ICD).
Mengxin Mu, Mengyu Guo, Jun Guan, Xiaofeng He, Mingdi Hu, Fene Gao, Klaus Müllen, Chendong Ji, Chunying Chen, Meizhen Yin   +9 more
wiley   +1 more source

Programmable Multi‐Axially Aligned Aerogels via Sequential Freeze‐Casting for Tailored Anisotropy and Tunable Mechanics

Advanced Science, EarlyView.
Conventional single‐gradient freeze‐casting typically produces unidirectional porous architectures with limited transverse connectivity. The Sequential Hybridization by Infiltration and Freeze‐casting Technique (SHIFT) addresses this constraint by integrating secondary aligned structures within a preformed primary scaffold.
Kiho Sung, Sungchul Shin
wiley   +1 more source

Comparative Study of Fisetin-Loaded Poloxamer 407 and Poloxamer 188 Mixed Micelles as Nanocarrier Systems. [PDF]

Molecules
Przybylski T, Czerniel J, Majchrzak-Celińska A, Jadach B, Krajka-Kuźniak V, Stawny M.   +5 more
europepmc   +1 more source

Matrix Stiffness Induces Endothelial Network Senescence

Advanced Science, EarlyView.
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song, Alexandra N. Rindone, Ya Guan, Connor D. Amelung, Prarthana Sanjay Daswani, Jennifer H. Elisseeff, Sharon Gerecht   +6 more
wiley   +1 more source

Long-Term Stabilization and Storage of Peptide-Based Coacervate through Tyrosine-Rich Sequences and Polyphenol Network. [PDF]

Nano Lett
Souri M, Halder M, Amer L, Hua Y, Lam B, Yim W, Jin Z, Jokerst JV.   +7 more
europepmc   +1 more source