Results 121 to 130 of about 50,534 (301)

Stability of various types of nanolipoprotein particles (NLPs) upon lyophilization [PDF]

open access: yes, 2011
Nanolipoprotein particles (NLPs) have many potential uses in modern medicine, from cancer therapeutics to vaccine alternatives. As with all pharmaceuticals, the ease of storage and adequate stability of a compound is always a question.
Fischer, Nicholas O   +2 more
core  

Heat‐Suppressing Projection Two‐Photon Lithography Enables High‐Throughput Sub‐Micrometer Manufacturing of Biopolymer Hydrogels for Tissue Engineering

open access: yesAdvanced Science, EarlyView.
The iLEAP technique integrates high‐throughput two‐photon lithography with extrusion printing, bridging sub‐micrometer precision and macroscopic scaffold fabrication. By employing a low‐exothermic photoinitiator, it mitigates thermal damage to biopolymers and preserves bioactivity.
Qifeng Guan   +11 more
wiley   +1 more source

Volterra model predictive control of a lyophilization plant

open access: yes, 2008
Lyophilization plants are widely used by pharmaceutical industries to produce stable dried medications and important preparations. Since, a Lyophilization cycle involves a high energy demands it is needed to be used an improved control strategy in order ...
Tsvetkov, Tsvetan D.   +3 more
core   +1 more source

Sticker Valence Governs Chain Collapse and Liquid‐Liquid Phase Separation in Peptide‐Inspired Associative Polymers

open access: yesAdvanced Science, EarlyView.
Peptide‐inspired associative polymers with arginine‐like guanidinium stickers and lysine‐like ammonium spacers undergo chain collapse and liquid‐liquid phase separation induced by reversible sticker associations. Sticker valence and tunable association strength jointly control the phase behavior, chain conformation, and interfacial cohesion of these ...
Seung‐Hwan Oh   +7 more
wiley   +1 more source

Monitoring Poloxamer 188 crystallization during typical freeze-drying conditions for biologics

open access: yesAAPS Open
This study investigates the phase behavior of Poloxamer 188 (P188) in aqueous solutions under conditions typical of pharmaceutical lyophilization processes.
Norbert Nagel   +4 more
doaj   +1 more source

Printable Piezoresistive Hybrid Hydrogels Based on 2D MoS2 for Flexible Pulse Sensing

open access: yesAdvanced Science, EarlyView.
Hybrid 1T‐MoS2‐based hydrogels are engineered through UV curing and 3D printing to achieve tunable electromechanical properties for wearable sensing. These soft architectures enhance mechanical stability and reproducible piezoresistive responses within the physiological pressure range.
Jenny Flores   +18 more
wiley   +1 more source

Studies on Lyophiled Cultures [PDF]

open access: yesJournal of Bacteriology, 1946
M D, APPLEMAN, O H, SEARS
openaire   +3 more sources

Plaque‐Hepatic Targeting Nanotherapy Disrupts the PCSK9‐LOX‐1 Axis to Suppress oxLDL in Atherosclerosis

open access: yesAdvanced Science, EarlyView.
Self‑amplifying PCSK9–LOX‑1 feedback axis drives atherosclerotic progression by promoting oxLDL generation and endothelial uptake. A dual‑targeting nanoplatform (siPCSK9@PEAL NPs‑aL) is constructed to simultaneously silence hepatic PCSK9 for lipid lowering and block plaque LOX‑1 for anti‑inflammation.
Yi Duan   +7 more
wiley   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

open access: yesAdvanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo   +10 more
wiley   +1 more source

A Comparison of Factors that Influence the Lyophilization Process [PDF]

open access: yes, 2007
The lyophilization (or freeze drying) process for agro-foods products depends on a series of technological factors that are in an inter-dependence with the process performance. This paper presents an expert method and its application.
Dumitru Mnerie   +7 more
core  

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