Results 121 to 130 of about 2,729,303 (155)
Some of the next articles are maybe not open access.
Analysis of Lysergic Acid Amide in Human Serum and Urine After Ingestion of Argyreia nervosa Seeds
Analytical and Bioanalytical Chemistry, 2012The ergot alkaloid lysergic acid amide (LSA) is a secondary plant constituent in a number of plants, but it is mainly present in considerable amounts in Convolvulaceae, like Argyreia nervosa. Due to its close structural similarity to lysergic acid diethylamide, LSA is considered as psychedelic and therefore promoted as so-called "legal high" in various
Stefan W Toennes +2 more
exaly +3 more sources
Role of the δ 8 Double Bond of Agroclavine in Lysergic Acid Amide Biosynthesis byClaviceps purpurea
Experientia, 1985Agroclavine, given to actively-growing sclerotial tissue of a strain of Claviceps purpurea which can not normally elaborate ergot alkaloids, was transformed by this tissue into lysergic acid amide with overall efficiency of approximately 40%. By contrast, festuclavine (8,9-dihydro-agroclavine) was not transformed, indicating specificity in the ...
P G Mantle
exaly +3 more sources
Stereoselective LSD-Like Activity in d-Lysergic Acid Amides of R- and S-2-Aminobutane
Journal of Medicinal Chemistry, 1992The (R)- and (S)-2-butylamides of d-lysergic acid were prepared and evaluated in behavioral and biochemical assays of 5-HT2 agonist activity. In rats trained to discriminate 0.08 mg/kg LSD tartrate from saline, both isomers completely substituted for the training stimulus.
David E. Nichols +2 more
exaly +3 more sources
Journal of Medicinal Chemistry, 1995
The 3-pentyl-, (R)- and (S)-2-pentyl-, 2-hexyl-, and 2-heptylamides of d-lysergic acid were synthesized and evaluated in biochemical and behavioral assays for LSD-like activity. In radioligand competition studies, the (R)-lysergamides were consistently more potent than the (S)-amides in displacing [3H]ketanserin from 5-HT2A receptors in rat cortical ...
David E. Nichols +2 more
exaly +3 more sources
The 3-pentyl-, (R)- and (S)-2-pentyl-, 2-hexyl-, and 2-heptylamides of d-lysergic acid were synthesized and evaluated in biochemical and behavioral assays for LSD-like activity. In radioligand competition studies, the (R)-lysergamides were consistently more potent than the (S)-amides in displacing [3H]ketanserin from 5-HT2A receptors in rat cortical ...
David E. Nichols +2 more
exaly +3 more sources
Journal of Chromatography A, 1965
Abstract A new method for the determination of lysergic acid amide, clavine alkaloids and isolysergic acid amide in extracts of morning glory seeds is described. The method is based on direct automatic densitometry of spots after chromatography on thin-layer plates. The method is more accurate and less time-consuming than existing ones. Several types
exaly +3 more sources
Abstract A new method for the determination of lysergic acid amide, clavine alkaloids and isolysergic acid amide in extracts of morning glory seeds is described. The method is based on direct automatic densitometry of spots after chromatography on thin-layer plates. The method is more accurate and less time-consuming than existing ones. Several types
exaly +3 more sources
Chromatographic Separation of Lysergic Acid Amide and Isolysergic Acid Amide in Morning Glory Seeds
Journal of Chromatography A, 1969Tetsukichi Niwaguchi, Takako Inoue
exaly +3 more sources
Chemischer Informationsdienst, 1974
AbstractDie Amidierung von Lysergsäure (I) in Gegenwart von Triphenylphosphit/Imidazol/ Phosphorsäure‐tris‐(dimethylamid) oder Phosphorsäure‐tris‐(dimethylamid)/Tosyl= Chlorid liefert die Verbindungen (II) und (III), wobei bei Verwendung des letztgenanr ten Reagens die Verbindungen (II) in 68‐75%iger und die Verbindungen (III) in bis 3 zu 8%iger ...
Y. NAKAHARA, T. NIWAGUCHI
openaire +1 more source
AbstractDie Amidierung von Lysergsäure (I) in Gegenwart von Triphenylphosphit/Imidazol/ Phosphorsäure‐tris‐(dimethylamid) oder Phosphorsäure‐tris‐(dimethylamid)/Tosyl= Chlorid liefert die Verbindungen (II) und (III), wobei bei Verwendung des letztgenanr ten Reagens die Verbindungen (II) in 68‐75%iger und die Verbindungen (III) in bis 3 zu 8%iger ...
Y. NAKAHARA, T. NIWAGUCHI
openaire +1 more source
Journal of Asthma Research, 1965
Although derivatives of d-lysergic acid have been employed in medicine for many years, the knowledge of their unique action on the central nervous system is dependent upon comparatively recent studies. The antiserotonin action of these compounds makes them of special value in the study of allergic mechanisms.
openaire +2 more sources
Although derivatives of d-lysergic acid have been employed in medicine for many years, the knowledge of their unique action on the central nervous system is dependent upon comparatively recent studies. The antiserotonin action of these compounds makes them of special value in the study of allergic mechanisms.
openaire +2 more sources
ChemInform Abstract: IMPROVED ACCESS TO AMIDE AND PEPTIDE DERIVATIVES OF THE LYSERGIC ACID SERIES
Chemischer Informationsdienst, 1978AbstractDie Amidierung von d‐Lysergsäure d‐(I) bzw. von d‐9,10‐Dihydrolysergsäure d‐(V) mit 2‐Amino‐butanol (+)‐(II) zu Methylergometrin (III) und Methylergometrinin (IV) bzw. zu 9,10‐Dihydromethylergometrin (VI) nach den TFA‐ bzw. H2SO4‐Mischanhydrid‐, DMF/SO3‐ und DCC/HO‐Bt‐Methoden wird untersucht.
G. LOSSE, W. MAHLBERG
openaire +1 more source
Effect of LSD-25 (lysergic acid — diethyl amide) on the Energetic Metabolism of the Brain of Rats
International Pharmacopsychiatry, 2017Authors investigated the effect of LSD-25, of chlorpromazine, and of a combination of both on three parts of the brain of white rats (I: cortex and white substance extending to the subcortex; II: subcortical ganglia and medulla oblongata; III: cerebellum) upon the level of total reducing substance, glycogen, lactic, and pyruvic acid, ATP, and anorganic
V. Máthé, G. Kassay
openaire +1 more source