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Antibacterial lysine analogs that target lysine riboswitches
Nature Chemical Biology, 2006Lysine riboswitches are bacterial RNA structures that sense the concentration of lysine and regulate the expression of lysine biosynthesis and transport genes. Members of this riboswitch class are found in the 5' untranslated region of messenger RNAs, where they form highly selective receptors for lysine.
Kenneth F, Blount +4 more
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Lysine−Bisglycidol Conjugates as Novel Lysine Cationic Surfactants
Langmuir, 2009The synthesis of a novel class of lysine-based cationic amphiphilic derivatives of the type N(epsilon),N(epsilon)'-bis(n-acyloxypropyl)-l-lysine methyl ester salts combining several hydroxyl functions and aliphatic chains of 12 or 14 carbon atoms is described. The compounds have one, two, three, and four alkyl chains.
Pinazo Gassol, Aurora +5 more
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Formation of thymine-lysine and cytosine-lysine adducts in DNA-lysine photoconjugate
Journal of Photochemistry and Photobiology B: Biology, 1995Lysine was covalently conjugated to calf thymus DNA by irradiation with UV light (wavelength, 253.7 nm). The results showed monofunctional covalent photobinding of lysine molecules with bases in DNA. Only the epsilon-amino group of lysine participated in the photoconjugation reaction. Thymine and cytosine were modified by 60% and 25% respectively.
N, Islam, R, Ali
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