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Effects of Initial Particle Size on the Tableting Properties of l-Lysine Monohydrochloride Dihydrate Powder

International Journal of Pharmaceutics, 2001
L-lysine monohydrochloride (LMH) dihydrate was crystallized and the resulting powder was sieved to obtain various size fractions. The influence of other factors, such as crystallinity and crystal shape, was minimized by using the same batch of crystals. Compression of smaller particles at low compaction pressures resulted in tablets of greater porosity.
Conroy Sun   +2 more
exaly   +3 more sources

Neuroprotective Effect of L-Lysine Monohydrochloride on Acute Iterative Anoxia in Rats With Quantitative Analysis of Electrocorticogram

Life Sciences, 1999
Lysine is one of the indispensible amino acids and L-lysine monohydrochloride (LMH) is widely available to public as a nonprescription oral supplement. Potential clinical usefulness of oral LMH supplements has been indicated in stroke, hypertension, and seizure induced by pentylenetetrazole (PTZ), etc.
G, Hong-Ping, K U, Bao-Shan
exaly   +3 more sources

L-Lysine Monohydrochloride

New England Journal of Medicine, 1960
THE usefulness of chloruretic, acidifying agents before the administration of mercurial diuretics is well established,1 since they have been shown to enhance the intensity of diuresis after injecti...
R P, LASSER   +2 more
openaire   +2 more sources

Influence of crystal shape on the tableting performance of L-lysine monohydrochloride dihydrate

Journal of Pharmaceutical Sciences, 2001
The purpose of this study is to understand the influence of crystal shape on the tableting performance of L-lysine monohydrochloride (LMH) dihydrate, using the method of data analysis developed by Joiris E et al. 1998. Pharm Res 15:1122-1130. Phase-pure crystals of LMH dihydrate, prism-shaped (S) and plate-shaped (T), were prepared by adjusting the ...
C, Sun, D J, Grant
openaire   +2 more sources

Synthesis of some metal chelates of L-lysine monohydrochloride

Thermochimica Acta, 1982
Jain et al. [I] reported the studies on Fe(I1) and Cd(I1) chelates of L-lysine monohydrochloride. In the present communication, attempts are made to report the complexes of L-lysine monohydrochloride with Mg(II), Mn(I1) and Hg(I1) metal ions. Although complexation behaviour of L-lysine has been extensively studied [2-61, a perusal of the literature [7 ...
Usha Sharma, Naresh Chandra
openaire   +1 more source

Kinetics of oxidation of lysine monohydrochloride by alkaline chloramine-T

Journal of Inorganic and Nuclear Chemistry, 1978
Abstract A kinetic study of the oxidation of lysine-monohydrochloride by chloramine-T in aqueous alkaline media has been made. The data follow the expression, −d d t [ CAT ]=k[ CAT ][ S − ] [ S − ]+[ NaOH NaOH ] which assumes the form, −d d t [ CAT ]=k′[ CAT ][ S − ] when [NaOH] ⪢; [S ...
B.S. Yadav, D.R. Singh, G. Chandra
openaire   +1 more source

Electro‐membrane reactor for the conversion of lysine monohydrochloride to lysine by in situ ion substitution and separation

Journal of Chemical Technology & Biotechnology, 2012
AbstractBACKGROUND: Commercially lysine (Lys) is produced as lysine monohydrochloride (LysCl). The presence of chloride ion (Cl−) in Lys makes it unfit for use in pharmaceutical and livestock feed industries. Various separation methods are required to achieve Lys from fermentation broths.
Kumar, Mahendra   +2 more
openaire   +2 more sources

l-lysine monohydrochloride dihydrate as novel elasto- and electrooptical materials

Materials Letters, 2008
Abstract We have studied optical parametrical effects (electrooptical and elastooptical ones) at wavelength 1150 nm generated by continuous He–Ne laser. We have found that the maximal value of the effective electrooptics coefficient is equal to about 12.6 pm/V and of the elastooptical coefficient was 12 · 10 14  m 2 /N and was achieved at temperature
K. Ozga   +3 more
openaire   +1 more source

Effect of l‐lysine monohydrochloride on cutaneous herpes simplex virus in the guinea pig

Journal of Medical Virology, 1989
AbstractThe effect of topical applications of crystalline lysine therapy on cutaneous herpes simplex virus (HSV) inoculations and subsequent dorsal root ganglia (DRG) infection was studied in male Hartley guinea pigs. Although HSV‐I was recovered from the inoculated sites from all animals, the L‐lysine‐treated skin remained clinically normal, whereas ...
E, Ayala, D, Krikorian
openaire   +2 more sources

Plasticity and Slip System of Plate-Shaped Crystals of L-Lysine Monohydrochloride Dihydrate

Pharmaceutical Research, 2002
To identify the slip system of L-lysine monohydrochloride dihydrate (LH) and to relate it to the deformation behavior under uniaxial compression.The indentation hardness of the [100] face and the indentation moduli of the [100] and [011] faces of plate-shaped single crystals of LH (LHP) were determined using Knoop and Berkovich indenters, respectively.
Rebanta, Bandyopadhya, David J W, Grant
openaire   +2 more sources

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