Results 131 to 140 of about 864,381 (312)
Peptide-induced lysis of human cells.
[A]. Human red blood cells (1%) were incubated with the listed peptides at the concentrations (μg/ml) indicated (PMX–polymyxin B). Released hemoglobin was quantitated spectrophotometrically and expressed as % lysis relative to dH2O (100% lysis). 0% lysis
Robert J. Schumacher (1246857) +2 more
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Ke-Qing Qian1, Heng Ye1, Yi-Wen Xiao1, Yong-Yi Bao2, Chun-Jian Qi11Department of Oncology; 2Department of Pathology, the Changzhou No. 2 People’s Hospital Affiliated to Nanjing Medical University, Changzhou, ChinaAbstract: Tumor lysis syndrome (
Heng Ye +4 more
core
An optimised direct lysis method for gene expression studies on low cell numbers
There is increasing interest in gene expression analysis of either single cells or limited numbers of cells. One such application is the analysis of harvested circulating tumour cells (CTCs), which are often present in very low numbers.
Thompson, Erik W. +4 more
core +1 more source
Lysogen stability is determined by the frequency of activity bursts from the fate‐determining gene
The ability of living cells to maintain an inheritable memory of their gene‐expression state is key to cellular differentiation. Bacterial lysogeny serves as a simple paradigm for long‐term cellular memory.
Chenghang Zong +4 more
doaj +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Tumor lysis syndrome in the emergency department: challenges and solutions
Silvio A Ñamendys-Silva,1,2 Juan M Arredondo-Armenta,1 Erika P Plata-Menchaca,2 Humberto Guevara-García,1 Francisco J García-Guillén,1 Eduardo Rivero-Sigarroa,2 Angel Herrera-Gómez,1 1Department of Critical Care ...
Herrera-Gómez A +6 more
core
Fibrin crosslinks and lysis rates
The effect of Factor XIII-induced crosslinking of fibrin on its subsequent lysis by plasmin has been further investigated due, in part, to conflicting reports in the literature on this issue.
Whitaker, A. N., Gaffney, P. J.
core +1 more source
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source

