Results 171 to 180 of about 1,236,497 (367)
A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang+4 more
wiley +1 more source
Yi‐Fei‐Jie‐Du‐Tang (YFJDT), a traditional Chinese medicine, has shown potential in lung cancer treatment by targeting key pathways. This study explores the mechanisms of YFJDT using bioinformatics, xenograft models, and A549 cells, demonstrating that YFJDT downregulates HIF1A, promotes ferroptosis, and inhibits epithelial‐mesenchymal transition (EMT ...
Shanshan Wang+6 more
wiley +1 more source
Lysis of Rhizobium melilotus in Agar Films by Bacteriophage [PDF]
F. H. S. Newbould
openalex +1 more source
THE ROLE OF SOCRATES, LYSIS, AND MENEXENUS IN PLATO’S LYSIS [PDF]
openaire +2 more sources
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang+6 more
wiley +1 more source
Optimization of rTDMH as a Reagent Toward Improving the Sensitivity of the RT-PCR Based Diagnosis for Mycobacterium Tuberculosis [PDF]
Current diagnostic tools being used for tuberculosis lack the speed and sensitivity necessary to successfully combat the current tuberculosis epidemic.
Bhatti, Alexandra
core
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav+5 more
wiley +1 more source
Microbiological and Clinical Significance of a New Property of Defective Lysis in Clinical Strains of Pneumococci [PDF]
A pneumococcal isolate that caused relapsing meningitis in a patient infected with human immunodeficiency virus (HIV) was found to display an unusual response to penicillin - rapid death but a striking lack of cellular lysis.
Davidson, M.+6 more
core
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng+12 more
wiley +1 more source