Gaucher Disease—Correlation of Lyso-Gb1 with Haematology and Biochemical Parameters [PDF]
MetabolitesBackground/Objectives: Gaucher disease (GD) is a lysosomal disorder caused by a deficiency of β-glucosidase. Disease-modifying therapies (DMTs) include enzyme replacement therapy (ERT) and substrate reduction therapy (SRT). Glucosylsphingosine (lyso-Gb1)
Simona D’Amore +3 more
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Increased Lyso-Gb1 Levels in an Obese Splenectomized Gaucher Disease Type 1 Patient Treated with Eliglustat: Unacknowledged Poor Compliance or Underlying Factors [PDF]
MetabolitesEliglustat (Cerdelga®) is a potent and specific inhibitor of the enzyme glucosylceramide synthase and serves as a substrate reduction therapy for adult patients with Gaucher disease type 1 (GD1).
Evelina Maines +8 more
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Lyso-GM2 ganglioside: a possible biomarker of Tay-Sachs disease and Sandhoff disease. [PDF]
PLoS ONE, 2011 To find a new biomarker of Tay-Sachs disease and Sandhoff disease. The lyso-GM2 ganglioside (lyso-GM2) levels in the brain and plasma in Sandhoff mice were measured by means of high performance liquid chromatography and the effect of a modified ...
Takashi Kodama +11 more
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Preparation of deacetyl-, lyso-, and deacetyl-lyso-GM3 by selective alkaline hydrolysis of GM3 ganglioside [PDF]
Journal of Lipid Research, 2001 Three methods (using GM3 quantities ranging from a few milligrams to grams) have been developed to prepare, in high yield, the three derivatives of ganglioside GM3 [α-Neu5Ac-(2-3)-β-Gal-(1-4)-β-Glc-(1-1)-ceramide]: deacetyl-GM3 [α-Neu-(2-3)-β-Gal-(1-4)-β-
Oscar Valiente +4 more
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Monitoring LSO/LYSO Crystal Based Calorimeters [PDF]
Journal of Physics: Conference Series, 2015 Precision light monitoring is important for keeping excellent energy resolution promised by LSO/LYSO crystals in severe radiation environment. In this paper, we report an investigation on the wavelength choice for monitoring LYSO crystal based calorimeters.
F. Yang, Liyuan Zhang, R. Y. Zhu
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Lyso-DGTS Lipid Derivatives Enhance PON1 Activities and Prevent Oxidation of LDL: A Structure–Activity Relationship Study [PDF]
Antioxidants, 2022 Paraoxonase 1 (PON1) plays a role in regulating reverse cholesterol transport and has antioxidative, anti-inflammatory, antiapoptotic, vasodilative, and antithrombotic activities.
Ali Khattib +4 more
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High Lyso-Gb3 Plasma Levels Associated with Decreased miR-29 and miR-200 Urinary Excretion in Young Non-Albuminuric Male Patient with Classic Fabry Disease [PDF]
Case Reports in Nephrology, 2019 Renal involvement is associated with a greater morbidity and mortality in Fabry disease. Pathological albuminuria, the first Fabry nephropathy clinical manifestation, can occur from early childhood, although histological lesions such as tubulo ...
Sebastián Jaurretche +2 more
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Dual-ended readout TOF-DOI PET detectors based on 3.2 mm and 1.6 mm pitch LYSO arrays [PDF]
EJNMMI PhysicsBackground The image quality of positron emission tomography (PET) can be significantly enhanced by using time-of-flight (TOF) and depth-of-interaction (DOI) information.
Haibo Wang +4 more
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A LYSO Calorimeter for the SuperB Factory [PDF]
Journal of Physics: Conference Series, 2011 The SuperB project is an asymmetric e+e? accelerator of 1036cm?2s?1 luminosity, capable of collecting a data sample of 50?75 ab?1 in five years of running. The SuperB electromagnetic calorimeter (EMC), that will be described in this paper, provides energy and direction measurement of photons and electrons, and is used for identification of electrons ...
C. Cecchi +10 more
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Effects of lysophospholipid on utilizing different sources and levels of carbohydrate in rainbow trout (Oncorhynchus mykiss) diet [PDF]
تغذیه آبزیان, 2021 The aim of the present study was to investigate the effects of dietary lysophospholipid and carbohydrates (rye and corn meal) on growth performance, blood and biochemical parameters in rainbow trout.
Batoul Adhami +4 more
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