Results 11 to 20 of about 24,044 (225)
Lyso-glycosphingolipids: presence and consequences [PDF]
Essays in Biochemistry, 2020 Abstract Lyso-glycosphingolipids are generated in excess in glycosphingolipid storage disorders. In the course of these pathologies glycosylated sphingolipid species accumulate within lysosomes due to flaws in the respective lipid degrading machinery.
Eijk, M. van +3 more
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Molecular Genetics and Metabolism Reports, 2023 Fabry disease (FD) is an inherited disease caused by deficient α-galactosidase A activity that is characterized by the accumulation of globotriaosylceramide (Gb3) and globotriaosylsphingosine (lyso-Gb3).
Atsumi Taguchi +3 more
doaj +1 more source
Pharmaceutics, 2021 Lyso-7 is a novel synthetic thiazolidinedione, which is a receptor (pan) agonist of PPAR α,β/δ,γ with anti-inflammatory activity. We investigated the cardiotoxicity of free Lyso-7 in vitro (4.5–450 nM), and Lyso-7 loaded in polylactic acid nanocapsules ...
Giani M. Garcia +6 more
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Lyso-Sulfatide Binds Factor Xa and Inhibits Thrombin Generation by the Prothrombinase Complex. [PDF]
PLoS ONE, 2015 Blood coagulation reactions are strongly influenced by phospholipids, but little is known about the influence of sphingolipids on coagulation mechanisms.
Subramanian Yegneswaran +4 more
doaj +1 more source
Nano-LC-MS/MS for Quantification of Lyso-Gb3 and Its Analogues Reveals a Useful Biomarker for Fabry Disease. [PDF]
PLoS ONE, 2015 Biomarkers useful for diagnosis and evaluation of treatment for patients with Fabry disease are urgently needed. Recently, plasma globotriaosylsphingosine (lyso-Gb3) and lyso-Gb3-related analogues have attracted attention as promising biomarkers of Fabry
Hideaki Sueoka +4 more
doaj +1 more source
Frontiers in Veterinary Science, 2023 Lysolecithin might increase ruminal and intestinal emulsification, leading to increased digestibility, but there is minimum information about which is the most appropriate phase to start supplementation and its impacts on feedlot performance and muscle ...
Rodrigo Dias Lauritano Pacheco +15 more
doaj +1 more source
RIPK3 Contributes to Lyso-Gb3-Induced Podocyte Death [PDF]
Cells, 2021 Fabry disease is a lysosomal storage disease with an X-linked heritage caused by absent or decreased activity of lysosomal enzymes named alpha-galactosidase A (α-gal A). Among the various manifestations of Fabry disease, Fabry nephropathy significantly affects patients’ morbidity and mortality.
So-Young Kim +10 more
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Animals, 2023 This study aimed to investigate the effect of dietary lysolecithin (LYSO) and lipase supplementation on productive performance, nutrient retention, and meat quality of broiler chicken fed a low energy diet.
Aziz Ahmad +6 more
doaj +1 more source
Characterization of three LYSO crystal batches [PDF]
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2015 We report on three LYSO crystal batches characterized at the Caltech crystal laboratory for future HEP experiments: 25 20 cm long crystals for the SuperB experiment; 12 13 cm long crystals for the Mu2e experiment and 623 14×14×1.5 mm^3 plates with five holes for a LYSO/W Shashlik matrix for a beam test at Fermilab.
Yang, Fan +3 more
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Metabolites, 2023 We conducted a lipidomic analysis of the whole body of female Aedes aegypti mosquitoes at different time points over the course of feeding and reproduction.
Meng-Jia Lau +6 more
doaj +1 more source