Results 31 to 40 of about 24,044 (225)
Migalastat HCl reduces globotriaosylsphingosine (lyso-Gb3) in Fabry transgenic mice and in the plasma of Fabry patients. [PDF]
PLoS ONE, 2013 Fabry disease (FD) results from mutations in the gene (GLA) that encodes the lysosomal enzyme α-galactosidase A (α-Gal A), and involves pathological accumulation of globotriaosylceramide (GL-3) and globotriaosylsphingosine (lyso-Gb3).
Brandy Young-Gqamana +15 more
doaj +1 more source
LYSO crystal testing for an EDM polarimeter [PDF]
Journal of Physics: Conference Series, 2017 Published by IOP Publ ...
Müller, Fabian +2 more
openaire +4 more sources
Lipids in Health and Disease, 2020 Background Ischemic heart disease (IHD) is a common cardiovascular disorder associated with inadequate blood supply to the myocardium. Chronic coronary ischemia leads to ischemic cardiomyopathy (ICM).
Lin Yang +9 more
doaj +1 more source
Characterization of Lysophospholipase D Activity in Mammalian Cell Membranes
CellsLysophosphatidic acid (LPA) is a lipid mediator that binds to G-protein-coupled receptors, eliciting a wide variety of responses in mammalian cells. Lyso-phospholipids generated via phospholipase A2 (PLA2) can be converted to LPA by a lysophospholipase D
Yuhuan Xie +7 more
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The Effect of Lyso-PAF on Ciliary Activity of Human Paranasal Sinus Mucosa in vitro
Mediators of Inflammation, 1994 The effect of lyso-PAF on ciliated cells was investigated in vitro. Normal mucosa was surgically obtained from human paranasal sinuses and incubated in the form of tissue culture.
T. Ganbo +4 more
doaj +1 more source
Analysis of Lyso-Globotriaosylsphingosine in Dried Blood Spots [PDF]
Annals of Laboratory Medicine, 2013 Recently, lyso-globotriaosylsphingosine (lyso-Gb3) was found to be elevated in plasma of treatment naive male patients and some female patients with Fabry Disease (FD). This study tested whether lyso-Gb3 could be analyzed in dried blood spots (DBS) from filter cards and whether concentrations are elevated in newborn infants with FD.
Johnson, Britt +9 more
openaire +2 more sources
Dietary and biliary phosphatidylcholine activates PKCζ in rat intestine[S]
Journal of Lipid Research, 2015 Chylomicron output by the intestine is proportional to intestinal phosphatidylcholine (PC) delivery. Using five different variations of PC delivery to the intestine, we found that lyso-phosphatidylcholine (lyso-PC), the absorbed form of PC ...
Shahzad Siddiqi, Charles M. Mansbach, II
doaj +1 more source
Lyso-Gb1 — a highly specific biomarker for Gaucher disease
Acta Haematologica PolonicaKarolina Słowik +4 more
openalex +4 more sources
LYSO based precision timing calorimeters
Journal of Physics: Conference Series, 2017 In this report we outline the study of the development of calorimeter detectors using bright scintillating crystals. We discuss how timing information with a precision of a few tens of pico seconds and below can significantly improve the reconstruction of the physics events under challenging high pileup conditions to be faced at the High-Luminosity LHC
Bornheim, A. +9 more
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Formation of Lyso-glycosphingolipids byStreptomycessp [PDF]
Bioscience, Biotechnology, and Biochemistry, 1995 The actinomycete strain Streptomyces sp. H37 produces a novel glycosphingolipid-degrading enzyme. This strain was capable of converting ganglioside GM1 to lyso-GM1. After cultivation for 5 days in medium containing GM1, peptone, and detergent, GM1 was found to be almost completely converted to lyso-GM1.
H, Ashida +6 more
openaire +2 more sources