Results 81 to 90 of about 24,044 (225)

Heart failure in two male patients with late‐onset Fabry mutation (IVS4 + 919G > A)

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 1508-1513, April 2025.
Xufei Yang   +3 more
wiley   +1 more source

Imaging malaria parasites across scales and time

open access: yesJournal of Microscopy, EarlyView.
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley   +1 more source

A facile method for controlling the reaction equilibrium of sphingolipid ceramide N-deacylase for lyso-glycosphingolipid production[S]

open access: yesJournal of Lipid Research, 2015
Lyso-glycosphingolipids (lyso-GSLs), the N-deacylated forms of glycosphingolipids (GSLs), are important synthetic intermediates for the preparation of GSL analogs. Although lyso-GSLs can be produced by hydrolyzing natural GSLs using sphingolipid ceramide
Feng-Tao Huang   +3 more
doaj   +1 more source

Kliničko ispitivanje preparata »Lyso-6«

open access: yesActa stomatologica Croatica : International journal of oral sciences and dental medicine, 1976
Na skupini od 47 selekcioniranih bolesnika, sa aftoznim eflorescencijama i subjektivnim simptomom pečenja oralne sluznice, autori su ispitivali terapijsko djelovanje preparata »Lyso-6«. Rezultati su pokazali da preparat Lyso-6 posjeduje pozitivna svojstva, kako s obzirom na brzinu epitelizacije ulkusa oralne sluznice i na intenzitet upale, tako i na ...
Dobrenić, Milutin   +1 more
openaire   +1 more source

High-energy radiographic imaging performance of LYSO

open access: yesNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2019
Abstract A comprehensive comparison of the dominant sources of radiation-induced blur for radiographic imaging system performance is made. End-point energies of 6, 10, 15, and 20 MeV bremsstrahlung photon radiation produced at the Los Alamos National Laboratory Microtron facility were used to examine the performance of large-panel cerium-doped ...
Duane Smalley   +11 more
openaire   +2 more sources

Understanding the dynamic nature of plant lipid anabolic and catabolic metabolism is key to sustainable oilseed engineering

open access: yesNew Phytologist, EarlyView.
Summary Plant‐derived oils are essential sources of reduced carbon and various fatty acid (FA) structures for food, biofuels, and the oleochemical industry. Despite extensive efforts, engineering mainstream oilseed crops to produce high levels of industrially valuable unusual FAs (UFAs) remains challenging.
Prasad Parchuri   +4 more
wiley   +1 more source

Preparation of lyso-GM1 (II3Neu5AcGgOse4-long chain bases) by a one-pot reaction.

open access: yesJournal of Lipid Research, 1992
A simple procedure is described for preparing lyso-GM1, a GM1 derivative that lacks the fatty acid moiety, starting from GM1 ganglioside using a one-pot reaction. Ganglioside deacylation was carried out in KOH/propan-1-ol in the absence of oxygen.
S Sonnino   +6 more
doaj   +1 more source

Plant Lipid Droplets and Derived Lipidic Nano‐Assemblies: Structure, Biogenesis and Pharmaceutical Applications

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Lipid droplets (LDs) serve as the primary storage site for neutral lipids in plant cells, with growing evidence supporting many additional biological roles, such as in lipid homeostasis, signalling, trafficking, inflammatory responses and inter‐organelle communication.
Abdulsamie Hanano   +2 more
wiley   +1 more source

Effect of Ambroxol chaperone therapy on Glucosylsphingosine (Lyso-Gb1) levels in two Canadian patients with type 3 Gaucher disease

open access: yesMolecular Genetics and Metabolism Reports, 2019
Type 3 Gaucher disease (GD3) is characterized by progressive neurological features in addition to the typical systemic manifestations. Enzyme replacement therapy (ERT), the main stay treatment for Gaucher disease (GD), is not efficacious for the ...
Behshad Charkhand   +4 more
doaj   +1 more source

Nanoengineered photosensitizers for photodynamic priming to overcome P‐glycoprotein‐mediated multidrug resistance

open access: yesPhotochemistry and Photobiology, EarlyView.
Verteporfin's subcellular localization governs its ability to deplete ATP. LysoPC‐conjugated VP accumulates in lysosomes and spares mitochondria, while liposomal and NanoVP formulations target mitochondria, where light activation triggers membrane depolarization and ATP depletion, overcoming resistance seen with free‐form VP. Abstract P‐glycoprotein (P‐
Idrisa Rahman   +7 more
wiley   +1 more source

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