Specific Integration of Temperate Phage Decreases the Pathogenicity of Host Bacteria
Temperate phages are considered as natural vectors for gene transmission among bacteria due to the ability to integrate their genomes into a host chromosome, therefore, affect the fitness and phenotype of host bacteria. Many virulence genes of pathogenic
Yibao Chen +20 more
doaj +1 more source
Bypass of a protein roadblock by a replicative DNA helicase [PDF]
Replicative DNA helicases generally unwind DNA as a single hexamer that encircles and translocates along one strand of the duplex while excluding the complementary strand (“steric exclusion”).
Hurwitz, Jerard +7 more
core +1 more source
Methods for generation of reporter phages and immobilization of active bacteriophages on a polymer surface [PDF]
Novel reporter bacteriophages are provided. Provided are compositions and methods that allow bacteriophages that are used for specific detection or killing of E. coli 0157:H7 to be propagated in nonpathogenic E.
Applegate, Bruce Michael +3 more
core +1 more source
Giant number fluctuations in microbial ecologies
Statistical fluctuations in population sizes of microbes may be quite large depending on the nature of their underlying stochastic dynamics. For example, the variance of the population size of a microbe undergoing a pure birth process with unlimited ...
Das, Dibyendu +2 more
core +1 more source
Propionibacterium acnes bacteriophages display limited genetic diversity and broad killing activity against bacterial skin isolates. [PDF]
UnlabelledInvestigation of the human microbiome has revealed diverse and complex microbial communities at distinct anatomic sites. The microbiome of the human sebaceous follicle provides a tractable model in which to study its dominant bacterial ...
Bowman, Charles +13 more
core +2 more sources
Designer Gene Networks: Towards Fundamental Cellular Control
The engineered control of cellular function through the design of synthetic genetic networks is becoming plausible. Here we show how a naturally occurring network can be used as a parts list for artificial network design, and how model formulation leads ...
Ackers +56 more
core +1 more source
Filamentous phages of Ralstonia solanacearum: double-edged swords for pathogenic bacteria [PDF]
Some phages from genus Inovirus use host or bacteriophage-encoded site-specific integrases or recombinases establish a prophage state. During integration or excision, a superinfective form can be produced.
Takashi Yamada
core +2 more sources
The PDZ domain of the SpoIVB serine peptidase facilitates multiple functions [PDF]
During spore formation in Bacillus subtilis, the SpoIVB protein is a critical component of the sigma (K) regulatory checkpoint. SpoIVB has been shown to be a serine peptidase that is synthesized in the spore chamber and which self-cleaves, releasing ...
Beebe K. D. +30 more
core +3 more sources
The prevalence and impact of lysogeny among oral isolates of Enterococcus faecalis
Bacterial phenotypic properties are frequently influenced by the uptake of extrachromosomal genetic elements, such as plasmids and bacteriophage genomes.
Roy H. Stevens +4 more
doaj +1 more source
A growing interest in healthy eating has lead to an increase in the consumption of vegetables, associated with a rising number of bacterial outbreaks related to fresh produce.
Pablo Quirós, Maite Muniesa
doaj +1 more source

