Results 11 to 20 of about 5,555 (166)
What makes a temperate phage an effective bacterial weapon? [PDF]
mSystemsTemperate bacteriophages (phages) are common features of bacterial genomes and can act as self-amplifying biological weapons, killing susceptible competitors and thus increasing the fitness of their bacterial hosts (lysogens).
M. J. N. Thomas +2 more
doaj +2 more sources
Temperate Bacteriophages—The Powerful Indirect Modulators of Eukaryotic Cells and Immune Functions
Viruses, 2021 Bacteriophages are natural biological entities that limit the growth and amplification of bacteria. They are important stimulators of evolutionary variability in bacteria, and currently are considered a weapon against antibiotic resistance of bacteria ...
Martyna Cieślik +5 more
doaj +1 more source
Mycobacteriophage Mcgavigan Uses Noncanonical Bxb1-Like Repressor for Heterotypic Superinfection Immunity. [PDF]
J Basic MicrobiolABSTRACT Mycobacteriophage Mcgavigan could be a promising candidate for use as a preventative agent against infections with Mycobacterium avium subsp. paratuberculosis. Bioinformatic analysis of the Mcgavigan genome revealed the presence of an operon containing a “Bxb1‐like” repressor.
Shafer N, Dubrule BE, De Buck J.
europepmc +2 more sources
Life, 2023 Antimicrobial resistance is rising as a major global public health threat and antibiotic resistance genes are widely spread among species, including human oral pathogens, e.g., Aggregatibacter actinomycetemcomitans.
Gaoyan Grace Tang-Siegel
doaj +1 more source
A φSa3int (NM3) Prophage Domestication in <i>Staphylococcus aureus</i> Leads to Increased Virulence Through Human Immune Evasion. [PDF]
MedComm (2020)Prophages play a significant role in modulating bacterial virulence and pathogenicity. Our results suggest domestication of φSa3int prophage leads to reduced phagocytosis mediating escape of S. aureus from human innate immunity. As such, targeted identification of mobile genetic elements (MGEs) in addition to species and strain identification may lead ...
Nepal R +9 more
europepmc +2 more sources
An Efficient, Counter-Selection-Based Method for Prophage Curing in Pseudomonas aeruginosa Strains
Viruses, 2021 Prophages are bacteriophages in the lysogenic state, where the viral genome is inserted within the bacterial chromosome. They contribute to strain genetic variability and can influence bacterial phenotypes. Prophages are highly abundant among the strains
Esther Shmidov +5 more
doaj +1 more source
Replication Region Analysis Reveals Non-lambdoid Shiga Toxin Converting Bacteriophages
Frontiers in Microbiology, 2021 Shiga toxin is the major virulence factor of enterohemorrhagic Escherichia coli (EHEC), and the gene encoding it is carried within the genome of Shiga toxin-converting phages (Stx phages).
Ann-Katrin Llarena +4 more
doaj +1 more source
Characterization of prophages in bacterial genomes from the honey bee (Apis mellifera) gut microbiome [PDF]
PeerJ, 2023 The gut of the European honey bee (Apis mellifera) possesses a relatively simple bacterial community, but little is known about its community of prophages (temperate bacteriophages integrated into the bacterial genome).
Emma K. Bueren +5 more
doaj +2 more sources
mBio, 2022 In this study, we describe the isolation and characterization of novel bacteriophage vB_EcoP_Kapi1 (Kapi1) isolated from a strain of commensal Escherichia coli inhabiting the gastrointestinal tract of healthy mice. We show that Kapi1 is a temperate phage
Kat Pick +3 more
doaj +1 more source
mBio, 2020 Colicins are toxins produced and released by Enterobacteriaceae to kill competitors in the gut. While group A colicins employ a division of labor strategy to liberate the toxin into the environment via colicin-specific lysis, group B colicin systems lack
Stefanie Spriewald +8 more
doaj +1 more source