Results 91 to 100 of about 2,977,925 (241)

Bacterial rotary export ATPases are allosterically regulated by the nucleotide second messenger cyclic-di-GMP [PDF]

, 2015
The widespread second messenger molecule cyclic di-GMP (cdG) regulates the transition from motile and virulent lifestyles to sessile, biofilm-forming ones in a wide range of bacteria. Many pathogenic and commensal bacterial-host interactions are known to
Abel, Aldridge, Amikam, Aragón, Barahona, Baraquet, Bell, Benach, Bingle, Boehm, Boyd, Brencic, Christen, Clare E.M. Stevenson, Compant, Cuppels, David M. Lawson, De, Duerig, Eleftheria Trampari, Emsley, Engl, Fazli, Gal, Galibert, Gledhill, Haas, Hengge, Hickman, Ho, Hughes, Iino, Imada, Jacob G. Malone, Jonas, Kelley, Krasteva, Krissinel, Kuchma, Kuchma, Kulasakara, Lee, Lindeberg, Little, Lovering, Lucchini, Lugtenberg, Macnab, Macnab, Martínez-Granero, Matilla, McNicholas, Miller, Minamino, Minamino, Minamino, Minamino, Minamino, Minamino, Minamino, Minamino, Moscoso, Moscoso, Naseby, Navazo, Nesper, Newell, Newell, Pfeilmeier, Pultz, Pérez-Mendoza, Qi, Rainey, Richard H. Little, Roelofs, Ryan, Schirmer, Solano, Srivastava, Starkey, Steiner, Story, Sudarsan, Tchigvintsev, Thomas Wilhelm, Tschowri, Wassmann, Wilhelm, Woodcock, Xin   +89 more
core   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Bacterial ‘Grounded’ Prophages: Hotspots for Genetic Renovation and Innovation

Frontiers in Genetics, 2019
Bacterial genomes are highly plastic allowing the generation of variants through mutations and acquisition of genetic information. The fittest variants are then selected by the econiche thereby allowing the bacterial adaptation and colonization of the ...
Bhaskar Chandra Mohan Ramisetty, Pavithra Anantharaman Sudhakari   +1 more
doaj   +1 more source

Photon‐to‐Heat Energy Harvesting Fluorescent Protein Coatings for Thermoelectrics

Advanced Science, EarlyView.
Fluorescent proteins (FPs) are used in light‐absorbing coatings on thermoelectric generators (TEGs) to convert light into heat and generate electricity. By tuning the properties of FP‐doped polymer matrices, photothermal efficiencies of up to 48% have been achieved.
Anna Zieleniewska, Sriram Kunchapudi, Stephanie Willeit, Rubén D. Costa   +3 more
wiley   +1 more source

Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Bioelectronic systems that enable seamless communication between electronic devices and living systems represent a transformative frontier in biotechnology. Among available methodologies, redox based signaling offers unique advantages due to its ubiquity in biology and compatibility with standard electrochemical equipment, expanding on ...
Eric VanArsdale, Monica Chu, Sally Wang, Divya Muthusamy, Eric Wold, Yi Liu, G. F. Payne, Tanya Tschirhart, W. E. Bentley   +8 more
wiley   +1 more source

Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries

iMetaOmics, EarlyView.
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo, Xiyang Dong, Jia‑Ling Li, Ji‐Cheng Yao, Ziqi Peng, Qi Li, Zi‐Wen Yang, Yang Yuan, Wen‑Jun Li, Pandeng Wang   +9 more
wiley   +1 more source

Automated Imaging of Cultured Bacteria in Picoliter Droplets by Coherent Anti‐Stokes Raman Scattering and Two‐Photon Excited Fluorescence Microscopy

Journal of Raman Spectroscopy, EarlyView.
We present an automated system that combines an image‐based fuzzy logic controller for precise positioning of microfluidic picoliter droplets with nonlinear microscopy, using CARS and TPEF modalities for detailed analysis of droplet composition. Time series and z‐stack images of E. coli, B. subtilis, and M. arborescens were recorded.
Fabian Ott, Ashkan Samimi, Sundar Hengoju, Tobias Meyer‐Zedler, Michael Schmitt, Miriam A. Rosenbaum, Jürgen Popp   +6 more
wiley   +1 more source

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

Small, EarlyView.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi, Benedikt Kronast, Jennifer Munkert, Lorenzo Sana, Marcus Koch, Heike Danzer, Sirka Dormeyer, Shuhan Jiang, Fabian Herrmann, Matthias Weiler, Anna Kashkanova, Vahid Sandoghdar, Mario M. Zaiss, Gregor Fuhrmann   +13 more
wiley   +1 more source

A Review of Phage Therapy for Aquaculture Applications: Efficacy, Health Ramifications and Research Challenges

Fish and Fisheries, EarlyView.
Bacteriophage therapy is characterised by numerous advantages, facilitating its diverse aquaculture application and efficacy as an antibiotic alternative mitigating the spread of antimicrobial‐resistant pathogens. Contributing to the modern reappraisal of the aquaculture application of bacteriophage therapy, challenges impeding its widespread ...
Louise James, Tamsyn M. Uren Webster, Gethin Thomas, Mathias Middelboe, Sofia Consuegra   +4 more
wiley   +1 more source

Structural investigation of human U6 snRNA recognition by spliceosomal recycling factor SART3 RNA recognition motifs

The FEBS Journal, EarlyView.
Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim, Kyeong‐Mi Bang, So Young An, Changkon Park, Ji‐Yeon Shin, Youngim Kim, Hyun Kyu Song, Jeong‐Yong Suh, Nak‐Kyoon Kim   +8 more
wiley   +1 more source