Results 121 to 130 of about 11,571 (196)

Skin microbiome engineering: Challenges and opportunities in skin diseases treatment

iMetaOmics, Volume 2, Issue 2, June 2025.
The skin microbiome plays a crucial role in skin health, influencing barrier integrity, immune responses, and disease susceptibility. Various interventions can reshape the microbiome, broadly categorized into targeted and untargeted approaches. Targeted strategies, such as phage therapy, engineered bacteria, and phage lysins, selectively modulate ...
Yiang Lyu, Juntao Shen, You Che, Lei Dai
wiley   +1 more source

Viral warriors: Screening water samples for bacteriophages against multiple drug resistant bacteria [PDF]

, 2016
Although mutation occurs randomly in nature and is passed randomly between bacterial species, the misuse and overuse of antibiotics in modern medicine has selected for antibiotic resistant organisms, resulting in an epidemic of antibiotic resistant ...

core  

Lysine acetylation modulates s‐OPA1 GTPase activity and oligomerization in mitochondrial membrane remodeling

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Mitochondrial dynamics are regulated by coordinated fission and fusion events that rely on key proteins and lipids organized spatially within the mitochondria. The dynamin‐related GTPase Optic Atrophy 1 (OPA1) is essential for inner mitochondrial membrane fusion and cristae structure maintenance.
Javaid Jabbar, Bakht Afroze, Naomi X. Y. Ling, Jonathan S. Oakhill, Isabelle Rouiller   +4 more
wiley   +1 more source

Regional Variation in Lytic and Lysogenic Viral Infection in the Southern Ocean and Its Contribution to Biogeochemical Cycling [PDF]

, 2012
Claire Evans, Corina P. D. Brussaard
openalex   +1 more source

Sulphur‐Acquisition Pathways for Cysteine Synthesis Confer a Fitness Advantage to Bacteria in Plant Extracts

Environmental Microbiology, Volume 27, Issue 6, June 2025.
Plant extracts are characterised by low levels of free cysteine (Cys). Bacterial uptake of glutathione (GSH), a cysteine‐containing tripeptide, is inhibited by the presence of other amino acids (AAs). Thus, the cysteine synthesis pathway through sulphate (SO42−) acquisition is necessary for growth in plant exudates and residues.
Kazuya Ishikawa, Saki Yamaguchi, Taketo Tsukaoka, Makoto Tsunoda, Kazuyuki Furuta, Chikara Kaito   +5 more
wiley   +1 more source

Delayed Bacterial Neutrophil Recruitment and Bacterial Bone Dispersion: New Identified Factors in Peri‐Prosthetic Joint Infection Development. Insights From an Adult Minipig Model

APMIS, Volume 133, Issue 6, June 2025.
ABSTRACT Clinically relevant animal models of peri‐prosthetic joint infection (PJI) are essential for studying infection initiation and progression. This study developed a PJI model in adult Göttingen minipigs, explicitly focusing on the early stages of infection to gain new perceptions of PJI initiation.
Katrine Top Hartmann, Anton Alexander Nolte Peterlin, Marie Høy Hansen, Julie Knippel Melsted Birch, Anders Odgaard, Bent Aalbæk, Mads Holm Christensen, Ida Thaarup, Thomas Bjarnsholt, Karen L. de Mesy Bentley, Andreas Petersen, Henrik Elvang Jensen, Louise Kruse Jensen   +12 more
wiley   +1 more source

Phenotypic characterization and genomic analysis of Limosilactobacillus fermentum phage

Current Research in Food Science
Limosilactobacillus (L.) fermentum is widely utilized for its beneficial properties, but lysogenic phages can integrate into its genome and can be induced to enter the lysis cycle under certain conditions, thus accomplishing lysis of host cells ...
Can Zhang, Xingyu Quan, Weiqi Lian, Runze Liu, Qiannan Wen, Xia Chen   +5 more
doaj  

Bacterial purine metabolism modulates C. elegans development and stress tolerance via DAF‐16

The FEBS Journal, Volume 292, Issue 11, Page 2771-2783, June 2025.
Purine metabolism is crucial for cellular function and is a conserved metabolic network from prokaryotes to humans, but remains poorly understood in metazoan. To investigate the impact of dietary components on purine metabolism and animal growth, we screened the effects of an Escherichia coli single‐gene deletion library on the growth of the nematode ...
Min Feng, Baizhen Gao, L. Rene Garcia, Qing Sun   +3 more
wiley   +1 more source

Stabilization of the catalytically active structure of a molybdenum‐dependent formate dehydrogenase depends on a highly conserved lysine residue

The FEBS Journal, Volume 292, Issue 12, Page 3165-3179, June 2025.
Molybdenum‐dependent formate dehydrogenases (Mo‐FDHs) contain a strictly conserved lysine residue (K44) in the vicinity of an electron‐transferring [4Fe‐4S] cluster and a catalytically active molybdenum atom coordinated by two molybdopterins (MPT‐1 and MPT‐2).
Feilong Li, Michael Lienemann
wiley   +1 more source

Protists are key players in the utilization of protein nitrogen in the arbuscular mycorrhizal hyphosphere

New Phytologist, Volume 246, Issue 6, Page 2753-2764, June 2025.
Summary While largely depending on other microorganisms for nitrogen (N) mineralization, arbuscular mycorrhizal fungi (AMF) can transfer N from organic sources to their host plants. Here, we compared N acquisition by the AMF hyphae from chitin and protein sources and assessed the effects of microbial interactions in the hyphosphere.
Anukool Vaishnav, Martin Rozmoš, Michala Kotianová, Hana Hršelová, Petra Bukovská, Jan Jansa   +5 more
wiley   +1 more source