Results 71 to 80 of about 11,571 (196)

Isolation and Genomic Characterization of the T4-Like Bacteriophage PM2 Infecting Pectobacterium carotovorum subsp. carotovorum

open access: yesThe Plant Pathology Journal, 2015
In order to control Pectobacterium carotovorum subsp. carotovorum, a novel virulent bacteriophage PM2 was isolated. Bacteriophage PM2 can infect 48% of P. carotovorum subsp. carotovorum and 78% of P. carotovorum subsp.
Jeong-A Lim, Dong Hwan Lee, Sunggi Heu
doaj   +1 more source

Characterization of the Cubamyces Menziesii Terpenome

open access: yesChemBioChem, EarlyView.
The genome of Cubamyces menziesii reveals 18 putative sesquiterpene cyclase genes. These genes are cloned and expressed in Escherichia coli, yielding 10 active enzymes. Using farnesyl diphosphate as substrate, the enzymes are analyzed, and the products characterized after bioconversion, uncovering diverse sesquiterpene structures. This study highlights
Létitia Leydet   +10 more
wiley   +1 more source

Phage inducible islands in the gram-positive cocci [PDF]

open access: yes, 2016
The SaPIs are a cohesive subfamily of extremely common phage-inducible chromosomal islands (PICIs) that reside quiescently at specific att sites in the staphylococcal chromosome and are induced by helper phages to excise and replicate.
A Bolotin   +47 more
core   +1 more source

Temperature-dependent carrier state mediated by H-NS promotes the long-term coexistence of Y. pestis and a phage in soil.

open access: yesPLoS Pathogens, 2023
The study of carrier state phages challenged the canonical lytic-lysogenic binary, and carrier state appears to be ubiquitous and ecologically important. However, the mechanisms of the carrier state are not well elucidated due to the limited phage models.
Lihua Yang   +9 more
doaj   +1 more source

Exploring the Stability and Substrate Profile of Transaminase from Silicibacter pomeroyi with Ancestral Sequence Reconstruction

open access: yesChemBioChem, EarlyView.
This study describes the successful identification of ancestral sequences N50 and N49, which have a longer half‐life of approximately four and two times the wild‐type Sp‐amine transaminase, respectively.. This approach effectively enhances the thermal stability of the transaminase.
Luyao Zhao   +4 more
wiley   +1 more source

Clade III Synthases Add Cyclic and Linear Terpenoids to the Psilocybe Metabolome

open access: yesChemBioChem, EarlyView.
The Psilocybe cubensis terpene synthases, CubB‐CubE, were investigated. Product formation assays identified CubB as a (3R,6E)‐(‐)‐nerolidol or linalool synthase, whereas CubC is a multiproduct synthase catalyzing the formation of β‐caryophyllene and other linear and cyclic sesquiterpenes/‐terpenoids.
Nick Zschoche   +7 more
wiley   +1 more source

Structural Basis of Regioselective Bromination of Tricyclic Tryptoline by the Tryptophan Halogenase Thal

open access: yesChemBioChem, EarlyView.
This study shows that the flavin‐dependent tryptophan halogenase Thal also regioselectively halogenates the tricyclic non‐native substrate tryptoline, a β‐carboline with various pharmacological activities. Interestingly, Thal brominates a different position of the shared pharmacophore indole in tryptoline than it does in tryptophan. A crystal structure
Simon Bork   +3 more
wiley   +1 more source

Synthesis, Characterization, and Cytotoxicity of Photochromic Molybdenum Oxide‐Doped Tungsten Oxide Polymeric Nanohybrid Films for Biomedical Applications

open access: yesChemPhysChem, EarlyView.
A novel and environmentally friendly photosensitive nanohybrid film made of chitosan and WO3MoO3 nanoparticles is prepared via a deep eutectic solvent‐assisted hydrothermal‐based method and a solvent casting protocol. The nanocomposite film shows a strong antibacterial effect on gram‐positive and gram‐negative cells, displaying cell viability above 90%
Shephrah Olubusola Ogungbesan   +7 more
wiley   +1 more source

The role of temperate bacteriophages in bacterial infection [PDF]

open access: yes, 2016
Bacteriophages are viruses that infect bacteria. There are an estimated 1031 phage on the planet, making them the most abundant form of life.
Andrew Millard   +24 more
core   +2 more sources

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