Results 81 to 90 of about 11,571 (196)

Isolation, characterisation and experimental evolution of phage that infect the horse chestnut tree pathogen, Pseudomonas syringae pv. aesculi [PDF]

, 2020
Bleeding canker of horse chestnut trees is a bacterial disease, caused by the bacterium Pseudomonas syringae pv. aesculi, estimated to be present in ~ 50% of UK horse chestnut trees.
Jackson, Robert W., James, Sarah L., Neuman, Benjamin W., Percival, Glynn, Rabiey, Mojgan   +4 more
core   +3 more sources

Phage‐mediated horizontal transfer of Salmonella enterica virulence genes with regulatory feedback from the host

iMeta, EarlyView.
In this study, we found evidence of phage‐mediated horizontal transfer of virulence genes in Salmonella enterica in global habitats from a molecular evolutionary perspective. Notably, csrA, a global regulator in Salmonella enterica, curbed horizontal gene transfer by inhibiting the cyclization and release of prophage.
Tianjing She, Demeng Tan, Jose Luis Balcazar, Ville‐Petri Friman, Danrui Wang, Dong Zhu, Mao Ye, Mingming Sun, Shujian Yuan, Feng Hu   +9 more
wiley   +1 more source

Bacterial rotary export ATPases are allosterically regulated by the nucleotide second messenger cyclic-di-GMP [PDF]

, 2015
The widespread second messenger molecule cyclic di-GMP (cdG) regulates the transition from motile and virulent lifestyles to sessile, biofilm-forming ones in a wide range of bacteria. Many pathogenic and commensal bacterial-host interactions are known to
Abel, Aldridge, Amikam, Aragón, Barahona, Baraquet, Bell, Benach, Bingle, Boehm, Boyd, Brencic, Christen, Clare E.M. Stevenson, Compant, Cuppels, David M. Lawson, De, Duerig, Eleftheria Trampari, Emsley, Engl, Fazli, Gal, Galibert, Gledhill, Haas, Hengge, Hickman, Ho, Hughes, Iino, Imada, Jacob G. Malone, Jonas, Kelley, Krasteva, Krissinel, Kuchma, Kuchma, Kulasakara, Lee, Lindeberg, Little, Lovering, Lucchini, Lugtenberg, Macnab, Macnab, Martínez-Granero, Matilla, McNicholas, Miller, Minamino, Minamino, Minamino, Minamino, Minamino, Minamino, Minamino, Minamino, Moscoso, Moscoso, Naseby, Navazo, Nesper, Newell, Newell, Pfeilmeier, Pultz, Pérez-Mendoza, Qi, Rainey, Richard H. Little, Roelofs, Ryan, Schirmer, Solano, Srivastava, Starkey, Steiner, Story, Sudarsan, Tchigvintsev, Thomas Wilhelm, Tschowri, Wassmann, Wilhelm, Woodcock, Xin   +89 more
core   +1 more source

Mutation-induced infections of phage-plasmids

Nature Communications, 2023
Phage-plasmids are extra-chromosomal elements that act both as plasmids and as phages, whose eco-evolutionary dynamics remain poorly constrained. Here, we show that segregational drift and loss-of-function mutations play key roles in the infection ...
Xiaoyu Shan, Rachel E. Szabo, Otto X. Cordero   +2 more
doaj   +1 more source

Adsorbable and Antimicrobial Amphiphilic Block Copolymers with Enhanced Biocompatibility

Macromolecular Materials and Engineering, EarlyView.
Permanently implanted biomaterials are prone to attract microorganisms and thus represent niches for infections in vivo. Absorbable, antimicrobial polymers have emerged as a promising option. To improve the compatibility of adsorbable antimicrobial polymers with human cells, the block composition of the polycationic segment is modified regarding the ...
Cornelia Wolf‐Brandstetter, Rafael Methling, Dirk Kuckling   +2 more
wiley   +1 more source

Programmable Protein‐DNA Composite Nanostructures: from Nanostructure Construction to Protein‐Induced Micro‐Scale Material Self‐Assembly and Functionalization

Small, EarlyView.
This study presents a modular platform that integrates engineered proteins with DNA nanostructures to create dynamic, multifunctional materials. By combining orthogonal protein‐protein and protein‐DNA conjugation strategies, the authors demonstrate controlled self‐assembly into nanofibers and nanorods, along with reversible enzyme activation.
Weijun Zhou, Žiga Strmšek, Jaka Snoj, Miha Škarabot, Roman Jerala   +4 more
wiley   +1 more source

Soil Viruses: A New Hope. [PDF]

, 2019
As abundant members of microbial communities, viruses impact microbial mortality, carbon and nutrient cycling, and food web dynamics. Although most of our information about viral communities comes from marine systems, evidence is mounting to suggest that
Emerson, Joanne B
core  

The Role of the Exo-Xis Region in Oxidative Stress-Mediated Induction of Shiga Toxin-Converting Prophages [PDF]

, 2015
Previous studies indicated that these genetic elements could be involved in the regulation of lysogenization and prophage induction processes. The effects were dramatic in Shiga toxin-converting phage Φ24B after treatment with oxidative stress-inducing ...
Bloch, Sylwia, Dydecka, Aleksandra, Licznerska, Katarzyna, Nejman-Faleńczyk, Bożena, Topka, Gracja, Węgrzyn, Alicja, Węgrzyn, Grzegorz   +6 more
core   +4 more sources

The gp44 Ejection Protein of Staphylococcus aureus Bacteriophage 80α Binds to the Ends of the Genome and Protects It from Degradation

Viruses, 2020
Bacteriophage 80α is a representative of a class of temperate phages that infect Staphylococcus aureus and other Gram-positive bacteria. Many of these phages carry genes encoding toxins and other virulence factors.
Keith A Manning, Terje Dokland
doaj   +1 more source

Lytic Transglycosylase Deficiency Increases Susceptibility to β‐lactam Antibiotics But Reduces Susceptibility to Vancomycin in Escherichia coli

Microbiology and Immunology, EarlyView.
ABSTRACT In Staphylococcus aureus, a gram‐positive pathogen, vancomycin‐resistant strains become susceptible to β‐lactam antibiotics, referred to as the “seesaw effect.” However, in gram‐negative bacteria, the phenomenon is less clear. Here, we analyzed the gene‐knockout effects of eight lytic transglycosylases (slt, mltA, mltB, mltC, mltD, mltE, mltF,
Takahiko Kimura, Kazuya Ishikawa, Ryosuke Nakagawa, Kazuyuki Furuta, Chikara Kaito   +4 more
wiley   +1 more source