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Signalling properties of lysophosphatidic acid
Trends in Pharmacological Sciences, 1993Lysophosphatidic acid (LPA) is the simplest natural phospholipid, primarily known as a membrane component and metabolic intermediate. However, a remarkable variety of biological effects of this compound have come to light, seemingly pointing to an additional role for LPA as a signalling molecule. In this review, Marcel Durieux and Kevin Lynch integrate
M E, Durieux, K R, Lynch
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Mitogenic Action of Lysophosphatidic Acid
1991Publisher Summary This chapter discusses the multiple biological effects of phosphatidic acid (PA) and lysophosphatidic acid (LPA), with particular emphasis on their growth factor-like activities. LPA and PA are the key intermediates in the early steps of phospholipid biosynthesis. They can exert their own biological effects. In particular, exogenous
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Lysophosphatidic Acid Signaling in Cancer Cells: What Makes LPA So Special?
Cells, 2021Pravita Balijepalli, Meier Kathryn E
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Lysophosphatidic Acid Signaling in Diabetic Nephropathy
International Journal of Molecular Sciences, 2019Donghee Kim, Hee-Sook Jun, Yoon Sin Oh
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Lysophosphatidic Acid and Hematopoiesis: From Microenvironmental Effects to Intracellular Signaling
International Journal of Molecular Sciences, 2020Hsinyu Lee +2 more
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Autotaxin–Lysophosphatidic Acid Signaling in Alzheimer’s Disease
International Journal of Molecular Sciences, 2018Timothy Moore +2 more
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