Results 121 to 130 of about 47,575 (225)
, 2019 In eukaryotic cells, the trans-Golgi network (TGN) serves as a platform for secretory cargo sorting and trafficking. In recent years, it has become evident that a complex network of lipid-lipid and lipid-protein interactions contributes to these key ...
Hausser, A., von Blume, J.
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Effect of Inhibition of the Lysophosphatidic Acid Receptor 1 on Metastasis and Metastatic Dormancy in Breast Cancer [PDF]
, 2017 Background Previous studies identified the human nonmetastatic gene 23 (NME1, hereafter Nm23-H1) as the first metastasis suppressor gene. An inverse relationship between Nm23-H1 and expression of lysophosphatidic acid receptor 1 gene (LPAR1, also known ...
Albaugh, Mary +11 more
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Decreased plasma gelsolin in the COVID-19-related acute respiratory distress syndrome
Türk Biyokimya DergisiThe aim of this study was to evaluate the potential roles of plasma gelsolin (pGSN), transforming growth factor-beta1 (TGF-β1), and lysophosphatidic acid (LPA) as profibrotic and immune modulatory markers in patients with acute respiratory distress ...
Gunturk Inayet +5 more
doaj +1 more source
Effect of Energy Metabolism on NF-kB activity in Ovarian Cancer [PDF]
, 2018 NF-kB is a transcription factor involved in cancer cell growth and survival. The activation of NF-kB can be assessed by monitoring phosphorylation of RelA p65 at Ser-536, which is a surrogate of the NF-kB transcription factor activation. The objective of
Bagri, Simren K
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Interaction of Gα₁₂ with Gα₁₃ and Gα_q signaling pathways [PDF]
, 2002 The G(12) subfamily of heterotrimeric G-proteins consists of two members, G(12) and G(13). Gene-targeting studies have revealed a role for G(13) in blood vessel development. Mice lacking the a subunit of G(13) die around embryonic day 10 as the result of
Gu, Jennifer L. +4 more
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[Lysophosphatidic acid: a "bioactive" phospholipid].
Medecine sciences : M/S, 2004 Lysophosphatidic acid (LPA) is a "bioactive" phospholipid able to generate growth factor-like activities in a wide variety of normal and malignant cell types. LPA is proposed to play an important role in normal physiological situations such as wound healing, vascular tone, vascular integrity, or reproduction.
openaire +2 more sources
AGPAT3 Regulates Immune Microenvironment in Osteosarcoma via Lysophosphatidic Acid Metabolism. [PDF]
Oncol ResSu S, Zeng Y, Chen J, Dong X.
europepmc +1 more source
Lysophosphatidic acid: a promising biomarker for diagnosing sepsis and predicting in-hospital mortality. [PDF]
Front ImmunolLi X, Li T, Xuan P, Wang H, Yang J.
europepmc +1 more source
Autotaxin and Lysophosphatidic Acid Circulating Levels Correlate with Body Mass Index in Obese Subjects with MASLD. [PDF]
Int J Mol SciTatoli R +7 more
europepmc +1 more source