Results 101 to 110 of about 2,548,802 (177)

CGI-58, The Causative Gene for Chanarin-Dorfman Syndrome, Mediates Acylation of Lysophosphatidic Acid

, 2008
Comparative Gene Identification–58 (cgi-58) is a member of $\alpha/\beta$-hydrolase family of proteins. Mutations in CGI-58 are shown to be responsible for a rare genetic disorder known as Chanarin-Dorfman syndrome, characterized by an excessive ...
Chandramohan, Chitraju, Rajasekharan, Ram, Ghosh, Ananda K, Ramakrishnan, Geetha   +3 more
core   +2 more sources

The Role of Lysophosphatidic Acid in Neuropsychiatric and Neurodegenerative Disorders

Future Pharmacology
Individuals suffering from diverse neuropsychiatric and neurodegenerative disorders often have comparable symptoms, which may underline the implication of shared hereditary influences and the same biological processes.
Simona Dedoni, Chiara Camoglio, Carlotta Siddi, Maria Scherma, Walter Fratta, Paola Fadda   +5 more
doaj   +1 more source

Lysophosphatidic acid and renal fibrosis.

, 2008
International audienceThe development of fibrosis involves a multitude of events and molecules. Until now the majority of these molecules were found to be proteins or peptides.
Salant, David, J., Gonzalez, Julien, Bascands, Jean-Loup, Schanstra, Joost, P., Pradère, Jean-Philippe, Klein, Julie, Valet, Philippe, Saulnier-Blache, Jean-Sébastien, Grès, Sandra   +8 more
core   +1 more source

Lysophosphatidic acid receptor agonists and antagonists (WO2010051053)

, 2011
Lysophosphatidic acid (LPA) is a bioactive lipid involved in signaling pathways that result in cell survival, proliferation, migration and invasion. These cellular responses are a critical element of both normal development as well as pathophysiology. In
Parrill, Abby L., Abby L Parrill
core   +1 more source

Role of lysophosphatidic acid in the retinal pigment epithelium and photoreceptors

, 2018
Role of lysophosphatidic acid in the retinal pigment epithelium and ...
RH Guymer (14594894), AJ Morris (14538839), SY Lim (9882272), HH Liang (14583917), A Pébay (13377525), A Conquest (13377672), M Daniszewski (13377510), Damian Hernandez (13066917), AW Hewitt (7715513), LA Rooney (15839735), GE Lidgerwood (14583920), P Allen (7719587), PP Connell (15839738)   +12 more
core  

Decreased plasma gelsolin in the COVID-19-related acute respiratory distress syndrome

Türk Biyokimya Dergisi
The aim of this study was to evaluate the potential roles of plasma gelsolin (pGSN), transforming growth factor-beta1 (TGF-β1), and lysophosphatidic acid (LPA) as profibrotic and immune modulatory markers in patients with acute respiratory distress ...
Gunturk Inayet, Seydel Gonul Seyda, Yazici Cevat, Topaloglu Ulas Serkan, Eren Esma, Yuksel Recep Civan   +5 more
doaj   +1 more source

Fatty Acid Species of Bio-Active Lysophosphatidic acid from Haploid Myxoamoebae of Physarum Polycephalum

, 1992
Fatty acid species of bio-active lysophosphatidic acid (LPA) fraction isolated from haploid myxoamoebae of Physarum polycephalum were analyzed. Physarum LPA fraction was purified by a combination of thin layer, and column chromatographies.
シマダ, ユキコ, Shimada, Yukiko, Takahashi, Yuko, Murakami-Murofushi, Kimiko, ムラカミ-ムロフシ, キミコ, タカハシ, ユウコ   +5 more
core  

Dysbiosis-Associated Lysophosphatidic Acid Primes Immune Checkpoint Inhibitor-Induced Intestinal Barrier Dysfunction via the Lysophosphatidic Acid Receptor 2-Myosin Light Chain Kinase Axis. [PDF]

Cell Mol Gastroenterol Hepatol
Xiong L, Huang J, Liu Q, Xia H, Zhu N, Xiang W, Xu W, Dong Y, Zhu R, Han Y, Rahman A, Xu H, Xie W, Luo Z, He W, Turner JR, Zhou Y, Hu R, Wang H, Zuo L.   +19 more
europepmc   +1 more source

Biology and function of the autotaxin/lysophosphatidic acid axis in cancer (Review). [PDF]

Mol Clin Oncol
Boccarelli A, Castellani S.
europepmc   +1 more source

Lysophosphatidic acid: mitogen and motility factor

, 2003
LPA (lysophosphatidic acid), the simplest of al glycerophospholipids, is a potent inducer of cell proliferation, migration and survival. It does so by activating its cognate G-protein-coupled receptors, four of which have been identified.
van Leeuwen, F N, Giepmans, B N G, van Meeteren, L A, Moolenaar, W.H., Meeteren, L.A. van, Moolenaar, W H, Leeuwen, F.N. van, Giepmans, B.N., Giepmans, B N G; id_orcid   +8 more
core