Results 91 to 100 of about 2,548,802 (177)

Autotaxin–Lysophosphatidic Acid Signaling in Alzheimer’s Disease

, 2018
The brain contains various forms of lipids that are important for maintaining its structural integrity and regulating various signaling cascades.
Manoj Govindarajulu, Sindhu Ramesh, Muralikrishnan Dhanasekaran, Vishnu Suppiramaniam, Timothy Moore   +4 more
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Lysophosphatidic acid as a phospholipid mediator: pathways of synthesis [PDF]

, 1997
From very recent studies, including molecular cloning of cDNA coding for membrane receptors, lysophosphatidic acid (LPA) reached the status of a novel phospholipid mediator with various biological activities.
Hugues Chap, Jean-Pierre Salles, Simon, Marie-Françoise, Geneviève Gueguen, Josette Fauvel, Marie-Françoise Simon, Gaits, Frédérique, Fauvel, Josette, Gaigé, Bernadette, Fourcade, Olivier, Salles, Jean-Pierre, Chap, Hugues, Olivier Fourcade, Frédérique Gaits, Mauco, Gérard, Gérard Mauco, Gueguen, Geneviève, Gassama-Diagne, Ama, Le Balle, François, Ama Gassama-Diagne, Bernadette Gaigé, François Le Balle   +21 more
core   +1 more source

Structural insights into the committed step of bacterial phospholipid biosynthesis

Nature Communications, 2017
The first step in bacterial phospholipid biosynthesis is the acylation of glycerol 3-phosphate to form lysophosphatidic acid. Here, the authors present the high resolution crystal structure of the glycerol 3-phosphate acyltransferase PlsY, a membrane ...
Zhenjian Li, Yannan Tang, Yiran Wu, Suwen Zhao, Juan Bao, Yitian Luo, Dianfan Li   +6 more
doaj   +1 more source

Lysophosphatidic acid induces the expression of ATF3.

, 2015
(A) SKOV-3 cells were treated with 5 μM lysophosphatidic acid (LPA) for the times indicated prior to assessment of ATF3 protein. (B) SKOV-3 and OVCAR-3 cells were treated with 5 μM LPA for the times indicated prior to qRT-PCR measurement and ...
Eileen J. Kennedy (374107), Wei Jia (136607), Ha T. Nguyen (801456), Aaron M. Beedle (563313), Mandi M. Murph (263899)   +4 more
core   +1 more source

A requirement for membrane cholesterol in the  -arrestin- and clathrin-dependent endocytosis of LPA1 lysophosphatidic acid receptors [PDF]

, 2005
Lysophosphatidic acid (LPA) stimulates heterotrimeric G protein signaling by activating three closely related receptors, termed ...
Trejo, Jo Ann, Radhakrishna, Harish, Jones, Kymry T., Urs, Nikhil M., Severin, Jamie E., Salo, Paul D.   +5 more
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A novel CuZnInS quantum dot-based ECL sensing system for lysophosphatidic acid detection

, 2017
A novel ECL sensing system was developed for lysophosphatidic acid detection based on AGM-CuInZnS QDs and GNs.
Wenying Gui, Hua Liu, Qiang Ma, Xueqian Chen   +3 more
core   +1 more source

Biochemical studies on plant glycerol-3- phosphate acyltransferase [PDF]

, 2003
sn-Glycerol-3-phosphate acyltransferase [G3PAT, PlsB (E.coli), EC 2.3.1.15] is an enzyme involved in glycerolipid biosynthesis, catalysing the acylation of glycerol-3-phosphate (G3P) to produce lysophosphatidic acid (LPA). Chilling tolerance in plants is
Hayman, Matthew William
core  

Structural characteristics of lysophosphatidic acid biological targets

, 2005
Lysophosphatidic acid (LPA; 1-acyl-3-phosphoglycerol) exerts its biological activity through both extracellular and intracellular targets. Receptor targets include the cell-surface G-protein-coupled receptors LPA1-4 and the nuclear PPAR-γ (peroxisome ...
Parrill, A. L.
core   +1 more source

The expression of lysophosphatidic acid and C-reactive protein in the course of the vulvar squamous cell carcinoma and the vulvar lichen sclerosus

Ginekologia Polska
OBJECTIVES: In the course of the study the differences regarding both C-reactive protein immune-expression and Lysophosphatidic Acid immune-expression between the stages and histologic grades of the vulvar cancer and the differences between the group of ...
Magda Piechowicz, Joanna Spaczynska, Piotr Sadowski, Tomasz Banas, Monika Kabzinska-Turek, Milosz Pietrus, Krzysztof Okon, Kazimierz Pitynski   +7 more
doaj   +1 more source

Relative expression level of lysophosphatidic acid receptors' mRNA against β-actin in cancer tissue and normal mammary gland tissue, evaluated using real-time RT-PCR: Lysophosphatidic acid receptor 1 (LPA1), LPA2 and LPA3

, 2011
Copyright information:Taken from "Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma"Breast Cancer Research 2004;6(6):R640-R646.Published online 22 Sep 2004PMCID:PMC1064082.Copyright © 2004 Kitayama et al., licensee ...
Hirokazu Nagawa (55605), Hiroyuki Arai (37989), Makoto Ishikawa (58495), Dai Shida (58493), Junken Aoki (58497), Kotaro Hama (58496), Akihiro Sako (58494), Joji Kitayama (55603)   +7 more
core   +1 more source