Results 81 to 90 of about 2,548,802 (177)

Acute exercise‐induced lipolysis and increase in levels of fatty acid esters of hydroxy fatty acids in adipose tissue are impaired in obese and aged mice

Experimental Physiology, Volume 111, Issue 10, Page 4457-4497, 1 October 2026.
Abstract Improving adipose tissue (AT) metabolism through exercise might increase production of lipokines from the fatty acid esters of hydroxy fatty acids (FAHFA) family. Although exercise training can increase insulin sensitivity and levels of specific FAHFA in AT and the circulation in humans, the effects of acute exercise on FAHFA levels remain ...
Marko Mitrovic, Olga Horakova, Martin Riecan, Veronika Kleinova, Tomas Cajka, Lenka Rossmeislova, Ondrej Kuda, Martin Rossmeisl   +7 more
wiley   +1 more source

Lysophosphatidic Acid (LPA) Induces Plasma Exudation and Histamine Release in Mice via LPA Receptors

Journal of Pharmacological Sciences, 2006
.: Lysophosphatidic acid (LPA), the simplest of the water-soluble phospholipids, can evoke various biological responses. The present study examined the activity of LPA to induce plasma exudation and histamine release in mice.
Terumasa Hashimoto, Hisayuki Ohata, Kazuo Honda   +2 more
doaj   +1 more source

The effect of lysophosphatidic acid on myometrial contractility and the mRNA transcription of its receptors in the myometrium at different stages of endometrosis in mares

BMC Veterinary Research
Background Endometrosis (chronic degenerative endometritis) results in morphological changes in the equine endometrium and impairs its secretory function. However, the effect of this condition on the myometrium remains unclear. Lysophosphatidic acid (LPA)
Katarzyna Karolina Piotrowska-Tomala, Anna Szóstek-Mioduchowska, Agnieszka Walentyna Jonczyk, Ewa Monika Drzewiecka, Michał Hubert Wrobel, Takuo Hojo, Graca Ferreira-Dias, Dariusz Jan Skarzynski   +7 more
doaj   +1 more source

Inhibitors of the Autotaxin-Lysophosphatidic Acid Axis and Their Potential in the Treatment of Interstitial Lung Disease: Current Perspectives

Clinical Pharmacology: Advances and Applications, 2020
Sabrina Zulfikar, Sarah Mulholland, Huzaifa Adamali, Shaney L Barratt Bristol Interstitial Lung Disease Service, North Bristol NHS Trust, Bristol, UKCorrespondence: Shaney L BarrattConsultant Respiratory Physician and Honorary Associate Researcher, North
Zulfikar S, Mulholland S, Adamali H, Barratt SL   +3 more
doaj  

Lysophosphatidic acid induces process retraction in CG-4 line oligodendrocytes and oligodendrocyte precursor cells but not in differentiated oligodendrocytes

, 2003
Lysophosphatidic acid is a growth factor-like signalling phospholipid. We demonstrate here that lysophosphatidic acid induces process retraction in central glia-4 cells and oligodendrocyte precursors.
Hotchin, N., Dawson, J., Rumsby, M., Lax, S., Hotchin, Neil; id_orcid, Dawson, J, Lax, Sian; id_orcid, Rumsby, M   +7 more
core   +1 more source

Modulatory role of lysophosphatidic acid on opioid receptor binding

, 1998
Arachidonic acid (AA) and lysophosphatidic acid (LPA) are two important signaling molecules generated by the hydrolysis of membrane phospholipids by the action of phospholipase A2 (PLA2) enzymes.
Öktem, Hüseyin Avni, Apaydin, S.
core   +1 more source

Autotaxin in Pathophysiology and Pulmonary Fibrosis

Frontiers in Medicine, 2018
Lysophospholipid signaling is emerging as a druggable regulator of pathophysiological responses, and especially fibrosis, exemplified by the relative ongoing clinical trials in idiopathic pulmonary fibrosis (IPF) patients.
Ioanna Ninou, Christiana Magkrioti, Vassilis Aidinis   +2 more
doaj   +1 more source

Lysophosphatidic acid stimulates thrombomodulin lectin-like domain shedding in human endothelial cells

, 2012
[[abstract]]"Thrombomodulin (TM) is an anticoagulant glycoprotein highly expressed on endothelial cell surfaces. Increased levels of soluble TM in circulation have been widely accepted as an indicator of endothelial damage or dysfunction.
黃元勵;Huang, Yuan-Li
core  

A study of synthetic approaches to 2-acyl DHA lysophosphatidic acid

, 2017
A salt formation suppresses acyl migration of DHA lysophosphatidic acid.
Toshimasa Itoh, Keiko Yamamoto, Yoshinori Yamamoto   +2 more
core   +1 more source

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

The Journal of Physiology, EarlyView.
Richard J. A. Wilson, Nicholas Jendzjowsky   +1 more
wiley   +1 more source