Results 81 to 90 of about 2,600,769 (206)

Effect of atherosclerosis on lysosomal cholesterol esterase activity in rabbit aorta

Journal of Lipid Research, 1977
Radiolabeled cholesteryl oleate, when incorporated into phospholipid vesicles, was hydrolyzed at acid pH by an enzyme present in rabbit aortic homogenates.
P Brecher, H Y Pyun, A V Chobanian
doaj   +1 more source

Real‐World Cost and Utilisation Burden of Diagnosed Metabolic Dysfunction‐Associated Steatotic Liver Disease in Patients With Type 2 Diabetes in the United States: A Retrospective Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study quantified the real‐world healthcare costs and utilisation associated with diagnosed metabolic dysfunction‐associated steatotic liver disease (MASLD) among adults with Type 2 diabetes (T2D). Methods We conducted a retrospective cohort study using IQVIA PharMetrics Plus Closed Health Plan data from January 2016 to June 2025 ...
Tien Hoang Tran, Hyung‐Seok Kim, Rozalina G. McCoy, Zafar Zafari   +3 more
wiley   +1 more source

Produção, caracterização e imobilização de lipase de fungo filamentoso isolado do efluente de abatedouro de frangos [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia QuímicaEste trabalho ilustra três linhas de pesquisa que se interconectam para atingir um objetivo final, o de verificar a ...
Pacheco, Sabrina Moro Villela
core  

Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormones-sensitive lipase in human subcutaneous abdominal adipocytes [PDF]

, 2007
Aim: In premenopausal women, hyper-androgenicity is associated with central obesity and an increased cardiovascular risk. We investigated the effects of dydrogesterone (DYD)(a non-androgenic progestogen) and norethisterone (NET)(an androgenic progestogen)
Sturdee, D. W., D. W. Sturdee, Palin, SL, Barnett, Anthony, S. L. Palin, K. C. McGee, Kumar, Sudhesh, McTernan, PG, McTernan, P. G., Barnett, A. H., Sturdee, David, Kumar, S, A. H. Barnett, McGee, K. C., McGee, KC, P. G. McTernan, Palin, S. L., S. Kumar   +17 more
core   +1 more source

Frequency of lysosomal acid lipase deficiency in patients with primary hyperlipidemia

Medicine Science, 2019
The aim of our study was to investigate the prevalence of LAL (lysosomal acid lipase) deficiency in patients with primary hyperlipidemia. Twenty-four patients with primary hyperlipidemia were included in the study.
Bahri Evren, yilmaz bilgic, Feyza Firat Atay, Ayse Nuransoy Cengiz, Yasir Furkan Cagin   +4 more
doaj   +1 more source

Metabolic Profiling of Circulating and Tumour‐Infiltrating T Cells Uncovers Bioenergetic Checkpoints Linked With Immune and Clinical Skewing in Melanoma Patients

Immunology, EarlyView.
In this study, we revealed the disturbed metabolic status of circulating and tumour‐infiltrating CD4+ and CD8+ T cells in melanoma patients through targeted metabolomic and lipidomic (on sorted subsets) and at single cell level using the SCENITH method.
Hugo Brouque, Kareem Mahdy, Stephane Mouret, Sylvain Henry, Camille Niveau, Mélanie Cettour‐Cave, Martin Pelosse, Florence de Fraipont, Julie Charles, Andrei Turtoi, Philippe Saas, Caroline Aspord   +11 more
wiley   +1 more source

Expressão, purificação e caracterização bioquímica de lipase recombinante de Staphylococcus xylosus e esterase recombinante de Lactobacillus plantarum [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-graduação em Ciência dos Alimentos, Florianópolis, 2010Esterases e lipases pertencem ao grupo das hidrolases e são enzimas que catalisam a clivagem e ...
Brod, Fábio Cristiano Angonesi
core  

Screening of Lysosomal acid lipase deficiency in patients with severe dyslipidemia and premature coronaryheart disease

, 2016
Objectives: To determine the prevalence of Lysosomal Acid Lipase (LAL) deficiency in patients with severe dyslipidemia and premature coronary heart ...
Marmelo, B., Correia, E., Oliveira, M., Marques, N., Antunes, H., Faria, R., Guedes, J., Azevedo, P., Azevedo, O., Azevedo, Pedro, Bento, D.   +10 more
core   +1 more source

The mediating role of genes in the influence of intestinal flora on type 2 diabetes and the screening of diagnostic markers

Journal of Diabetes Investigation, EarlyView.
Using Mendelian randomization, TWAS/eQTL analysis, machine learning, and single‐cell RNA sequencing, this study identified gut microbiota taxa causally linked to type 2 diabetes, candidate mediator genes, and diagnostic markers (BEND7, BLVRA, C1orf85, and LAMC1).
Yu‐yang Chen, Yi‐fan Shi, Xin‐yue Zhang, Jing‐yue Zhang, Shi‐mao Zhang, Heng‐xia Zhao, De‐liang Liu   +6 more
wiley   +1 more source

The Liver and Lysosomal Storage Diseases: From Pathophysiology to Clinical Presentation, Diagnostics, and Treatment

Diagnostics
The liver, given its role as the central metabolic organ, is involved in many inherited metabolic disorders, including lysosomal storage diseases (LSDs).
Patryk Lipiński, Anna Tylki-Szymańska
doaj   +1 more source