Results 1 to 10 of about 158,851 (164)

Therapeutic targeting of lysosome-triggered inflammatory channels in nasal and upper-airway allergic conditions. [PDF]

Front Immunol
Yu H, Zheng Y, Wu D, Zhou L, Jiang K, Tian K, Shen N.   +6 more
europepmc   +1 more source

Mitochondria-lysosome coupling contributes to lysosome acidification and aging. [PDF]

Mol Cell
Liu Q, Yoo S, Zhang ZA, Li L, Su H, Vannur L, Wooldredge AC, Hughes JB, Desprez PY, Hao N, Lithgow G, Andersen JK, Hansen M, Campisi J, Zhou C.   +14 more
europepmc   +1 more source

Autophagy-lysosome networks in oligodendrocytes: a dynamic framework for myelin integrity. [PDF]

Front Cell Dev Biol
Jiménez-Ridruejo I, Plaza-Zabala A.
europepmc   +1 more source

Noncanonical PI(4,5)P₂ coordinates lysosome positioning through cholesterol trafficking. [PDF]

Sci Adv
Loughran RM, Arora GK, Sun J, Llorente A, Crabtree S, Zhang CY, Ly K, Huynh RL, Cho W, Emerling BM.   +9 more
europepmc   +1 more source

Defect in lysosomal enzyme trafficking and sorting is associated with irreversibility of pulmonary arterial hypertension. [PDF]

Front Cardiovasc Med
Xiao G, Meng Y, Du Z, Liu Z, Yu H, Wang H, Nie L, Liu X, Lan X, Duan Y, Xiong J, Liu Z.   +11 more
europepmc   +1 more source

"Artificial platelet injection system": a plug-and-play platelet-based lysosome-targeting chimera for targeted protein degradation. [PDF]

Bioact Mater
Zou C, Zhu H, Tang Y, Guo S.
europepmc   +1 more source

"Micro-managing" immune activation and protein turnover: microglial lysosomes in the context of health and disease. [PDF]

NPJ Dement
Somodji EA, Gowrishankar S.
europepmc   +1 more source

mTOR Inhibition Drives Mutation-Specific Remodeling of Lysosomal and Autophagic Pathways and GCase Activity in PBMC-Derived Macrophages from Patients with GBA1-Associated Parkinson's Disease. [PDF]

Curr Issues Mol Biol
Bezrukova A, Basharova K, Emelyanov A, Lavrinova A, Krapova A, Galkina E, Skudarnova E, Baydakova G, Miliukhina I, Zakharova E, Pchelina S, Usenko T.   +11 more
europepmc   +1 more source

Illuminating compartmentalized AMPK signaling in single cells. [PDF]

Biochem J
Jhawar A, Parks K, Schmitt DL.
europepmc   +1 more source

Holistic therapeutic philosophy: Boost a cascade communication between endoplasmic reticulum-mitochondria-lysosome to overload intracellular Ca²⁺ and initiate chemoimmunotherapy. [PDF]

Mater Today Bio
Su Y, Fang H, Hao W, Ding ZH, Tang L, Yu ZH, Su Z.   +6 more
europepmc   +1 more source