Results 151 to 160 of about 123,112 (260)

Clinical implementation of gene panel testing for lysosomal storage diseases [PDF]

, 2018
Alexander Gheldof, Sara Seneca, Katrien Stouffs, Willy Lissens, Anna Jansen, Hilde Laeremans, Patrick Verloo, An‐Sofie Schoonjans, Marije Meuwissen, Diana Bârcă, Geert A. Martens, Linda De Meırleır   +11 more
openalex   +1 more source

Calcium retinoate nanoparticle mediated microglial polarization to regulate inflammatory microenvironment for therapy of neuroinflammatory disease

BMEMat, EarlyView.
A nano‐drug based on retinoic acid and calcium is developed, which can be rapily endocytosed by microglia and decomposed into small molecule/ion storms in lysosomes. This nano‐drug regulates microglial phenotype switching from M1 to M2 while indirectly guiding neuronal differentiation of endogenous neural stem cells, thereby ameliorating ...
Shuo Zhang, Yuan Yao, Wenfeng Shao, Jiapei Shi, Benjie Wei, Chunhui Sun, Jingang Wang, Jiaming Shi, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Na Ren, Yuchun Tang, Wenjuan Zhou, Shuping Wang   +13 more
wiley   +1 more source

Experimental Models of CNS Deficits in Lysosomal Storage Diseases

, 2023
Andrei Lebedev, М. М. Kotova, Tatiana O. Kolesnikova, David S. Galstyan, Allan V. Kalueff   +4 more
openalex   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Prenatal Workup of Mucopolysaccharidosis (MPS) III A Lysosomal Storage Disease

, 2016
Shikha Seth, Priya Sharma, Soniya Vishwakarma, Deepshikha Deepshikha   +3 more
openalex   +1 more source

Fusion of lysosomes with secretory organelles leads to uncontrolled exocytosis in the lysosomal storage disease mucolipidosis type IV

EMBO Reports, 2015
Soonhong Park, Malini Ahuja, Min Seuk Kim, G. Brailoiu, Archana Jha, Mei Zeng, Maryna Baydyuk, Ling-Gang Wu, C. Wassif, F. Porter, P. Zerfas, M. Eckhaus, E. Brǎiloiu, D. Shin, S. Muallem   +14 more
semanticscholar   +1 more source

Mechanism and role of regulated cell death in tumor immunity and immunotherapy

Cancer Communications, EarlyView.
Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu, Yan Li, Bingjie Lian, Yitao Mao, Luqing Zhao   +4 more
wiley   +1 more source

Placental Findings in Lysosomal Storage Disease Diagnosis: A Case Report of Galactosialidosis. [PDF]

Case Rep Pathol, 2020
Libbrecht S, Eyskens F, Declercq S, Colpaert C.   +3 more
europepmc   +1 more source

Recent Advances of In Situ Anticancer Nanomedicine from Enzyme‐Instructed Self‐Assembly

ChemNanoMat, EarlyView.
This review summarizes advances in enzymatic self‐assemblies for generating in situ anticancer nanomedicine over the past five years. It highlights the unique features of enzyme substrates for in situ anticancer nanomedicine by discussing the representative examples.
Linrui Zou, Meihui Yi, Bing Xu
wiley   +1 more source

Ultrastructural pathology of rectum and skin biopsy specimens in lysosomal storage diseases.

, 1990
Masako Taniike, Tsunekazu Yamano, M. Shimada, Koji Inui, Shintaro Okada   +4 more
openalex   +2 more sources