Results 211 to 220 of about 123,112 (260)

Development of phytotherapeutic nanoformulation containing Gypsophila eriocalyx and its evaluation as a candidate formulation for osteoporosis treatment on human bone marrow stem cells

Phytochemical Analysis, EarlyView.
Abstract Introduction Osteoporosis, one of the common bone diseases, manifests itself as a decrease in bone mass. Recently, the use of medicinal plants in the search for effective and low‐toxicity therapeutics for the prevention or treatment of osteoporosis has become a trending topic.
Sibel Kaymak, Ozan Baris Kurtur, Bahar Gok, Yasemin Budama‐Kilinc, Serda Kecel‐Gunduz, Ebru Özdemir Nath, Murat Kartal   +6 more
wiley   +1 more source

Development of Organelle Replacement Therapy Using a Stearyl-Polyhistidine Peptide against Lysosomal Storage Disease Cells. [PDF]

Molecules, 2019
Hayashi T, Okamoto R, Kawano T, Iwasaki T.   +3 more
europepmc   +1 more source

Digital microfluidic platform for multiplexing enzyme assays: implications for lysosomal storage disease screening in newborns.

Clinical Chemistry, 2011
R. Sista, A. Eckhardt, Tong Wang, C. Graham, J. Rouse, S. Norton, V. Srinivasan, M. Pollack, A. Tolun, Deeksha S. Bali, D. Millington, V. Pamula   +11 more
semanticscholar   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Vacuolated Lymphocytes as a Clue for Diagnosis of Lysosomal Storage Disease like GM1 Gangliosidosis. [PDF]

Indian J Hematol Blood Transfus, 2018
Vasei M, Abolhasani M, Safavi M.
europepmc   +1 more source

Clinical effect and safety profile of recombinant human lysosomal acid lipase in patients With cholesteryl ester storage disease

Hepatology, 2013
M. Balwani, C. Breen, Gregory M Enns, P. Deegan, T. Honzík, Simon A. Jones, John P. Kane, V. Malinová, Reena Sharma, E. Stock, V. Valayannopoulos, J. Wraith, J. Burg, S. Eckert, E. Schneider, Anthony G. Quinn   +15 more
semanticscholar   +1 more source

TREM2 Downregulation Disrupts Microglial Function and Synaptic Pruning Through RA/RARα Signaling: Mechanisms Underlying Autism‐Like Behaviors

Pediatric Discovery, EarlyView.
Downregulation of TREM2 induces autism‐like behaviors in healthy rats by impairing microglial function and triggering aberrant synaptic pruning. RA/RARα signaling pathway modulates alterations in TREM2 expression. Serum sTREM2 levels correspond to alterations in brain TREM2 expression.
Min Lu, Kexin Bai, Yali Bai, Yuan Miao, Tingjiao Zhao, Yi Yang, Jie Chen, Ting Yang, Tingyu Li, Hua Wei   +9 more
wiley   +1 more source

Cholesteryl Ester Storage Disease: Protean Presentations of Lysosomal Acid Lipase Deficiency

Journal of Pediatric Gastroenterology and Nutrition - JPGN, 2013
Bingnan Zhang, Anthony F. Porto
semanticscholar   +1 more source

LYSOSOMAL STORAGE DISEASES: DIFFICULTIES IN DIFFERINTIAL DIAGNOSIS

, 2019
TATIANA Y. POMYTKINA, ALEXANDRA Y. DAVYDOVA   +1 more
openalex   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source