Results 141 to 150 of about 174,460 (337)

Lysosomes

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009
Gieselmann, Volkmar, Braulke, Thomas
openaire   +2 more sources

Self‐Powered α Radionuclide Nanomedicine: Mitochondria‐Targeted Multimodal Energy Recycling for Amplified Radioimmunotherapy

open access: yesAdvanced Materials, EarlyView.
A multifunctional nanomedicine co‐loading of the α‐emitter 223RaCl2 within iron‐based MOFs is developed. Precisely targeted to mitochondria, it exploits the full decay spectrum to synchronize three therapeutic actions: direct α‐particle ionization, self‐powered catalytic H2O2 generation via secondary electrons, and immunogenic cell death induction ...
Xian Li   +7 more
wiley   +1 more source

The Evaluation of Mefloquine Drug Repurposing on Acute Myeloid Leukemia [PDF]

open access: yes, 2018
The aim of this study is to observe cell proliferation, cell viability, apoptosis, and autophagy on acute myeloid leukemia (AML) cell lines, NB4 and U937, with the drug repurposing of mefloquine (MQ).
Corey, Seth   +3 more
core   +1 more source

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

open access: yesAdvanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac   +7 more
wiley   +1 more source

Red Multi‐Resonant Thermally Activated Delayed Fluorescence Emitters as Bioimaging Agents

open access: yesAdvanced Optical Materials, EarlyView.
Multi‐resonant thermally activated delayed fluorescence (MR‐TADF) emitters have attracted strong interest for use in electroluminescent devices due to their high photoluminescence quantum yield and narrowband emission. These properties, along with red emission, are also crucial for bioimaging probes.
Changfeng Si   +4 more
wiley   +1 more source

STUDIES ON LYSOSOMES [PDF]

open access: bronze, 1962
Gerald Weissmann, Lewis Thomas
openalex   +1 more source

Cold Plasma Generates a Localized Inflammatory Response and Promotes Muscle Repair

open access: yesAdvanced Therapeutics, EarlyView.
The immediate tissue response to plasma is a pro‐inflammatory response which is characterized by collagen clumping, innate immune cell infiltration, enhanced metabolic processes, and decreased apoptosis. The long‐term tissue response (4‐ and 14‐days) to plasma treatment is characterized by a decreased inflammatory response, decreased adipogenesis, and ...
Carly J. Smith   +9 more
wiley   +1 more source

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