Results 141 to 150 of about 249,586 (383)
Advanced Functional Materials, EarlyView.Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang +9 more
wiley +1 more source
Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]
, 2016 Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
core +1 more source
Advanced Functional Materials, EarlyView.The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar +6 more
wiley +1 more source
Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells. [PDF]
, 2016 Alpha1,2-fucosyltransferases, FUT1 and FUT2, which transfer fucoses onto the terminal galactose of N-acetyl-lactosamine via α1,2-linkage have been shown to be highly expressed in various types of cancers.
Cho, Huan-Chieh +5 more
core
Studies on the mode of action of excess of vitamin A. 4. The specificity of the effect on embryonic chick-limb cartilage in culture and on isolated rat-liver lysosomes [PDF]
, 1962 HB Fell, JT Dingle, Michael Webb
openalex +1 more source
Metal Nanoclusters for Cancer Imaging and Treatment
Advanced Functional Materials, EarlyView.This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu +5 more
wiley +1 more source
The osmotic stability of lysosomes from adult and foetal guinea-pig liver tissue [PDF]
, 1969 Julienne M. Turnbull, M. W. Neil
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Neural Regeneration ResearchParkinson’s disease is a common neurodegenerative disease with movement disorders associated with the intracytoplasmic deposition of aggregate proteins such as α-synuclein in neurons.
Fengjuan Jiao +3 more
doaj +1 more source
Journal of Lipid Research, 2014 Lysosomal integral membrane protein-2 (LIMP2) mediates trafficking of glucocerebrosidase (GBA) to lysosomes. Deficiency of LIMP2 causes action myoclonus-renal failure syndrome (AMRF).
Paulo Gaspar +11 more
doaj +1 more source