Results 151 to 160 of about 249,586 (383)
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
CYTOPLASMIC COMPONENTS IN HEPATIC CELL LYSOSOMES [PDF]
Thomas P. Ashford, Keith R. Porter
openalex +1 more source
Smart Nanogels as Enzyme‐Driven Nanomotors for Navigating Viscous Physiological Barriers
Two families of urease‐powered nanomotors (NMs), with and without a p‐(2‐hydroxyethyl methacrylate) (p‐HEMA) shell, have been successfully prepared. Both types exhibit effective motion in highly viscous synovial fluid media at low urea concentrations (25 mM).
David Esporrín‐Ubieto+6 more
wiley +1 more source
Lysosomes support diverse cellular functions by acting as sites of macromolecule degradation and nutrient recycling. The degradative abilities of lysosomes are conferred by a lumen that is characterized by an acidic pH and which contains numerous hydrolases that support the breakdown of major cellular macromolecules to yield cellular building blocks ...
openaire +2 more sources
This comprehensive review explores therapeutic titanium implants designed to enhance integration and provide superior antibacterial efficacy. It is focused on anodized titanium implants with titania nanotubes (TNTs) loaded with nanoparticles (NPs) for local therapeutic release, enhancing bioactivity and bactericidal functions.
Divya Chopra+5 more
wiley +1 more source
ELECTRON MICROSCOPY OF LYSOSOME-RICH FRACTIONS FROM RAT THYMUS ISOLATED BY DENSITY-GRADIENT CENTRIFUGATION BEFORE AND AFTER WHOLE-BODY X-IRRADIATION [PDF]
Y.E. Rahman
openalex +1 more source
The lysosome as an imperative regulator of autophagy and cell death
K. K. Mahapatra+5 more
semanticscholar +1 more source
Lysosome targeted therapies in hematological malignancies
Lysosomes are dynamic organelles integral to cellular homeostasis, secretory pathways, immune responses, and cell death regulation. In cancers, lysosomes become dysregulated to sustain proliferative signaling, metabolism, and invasion.
Madhumita S. Manivannan+2 more
doaj +1 more source
The new generation nanobomb, termed the stealth nanobomb, is fabricated through self‐assembly using a polymeric carbon monoxide carrier (PLGA(CO)), small molecule near‐infrared‐active agents (2TT‐OC46B), and phospholipid polyethylene glycol (DSPE‐mPEG2000). The stealth nanobomb can circulate in the bloodstream and specifically target pancreatic cancer,
Gongcheng Ma+10 more
wiley +1 more source
THE LARGE-SCALE SEPARATION OF PEROXISOMES, MITOCHONDRIA, AND LYSOSOMES FROM THE LIVERS OF RATS INJECTED WITH TRITON WR-1339 [PDF]
Federico Leighton+6 more
openalex +1 more source