Results 61 to 70 of about 3,746 (167)
Coumarin‐Augmented Thiazole Hybrids as Dual Anticancer and Antibacterial Agents
Compound 13, a coumarin‐thiazole hybrid, is shown engaging the ATP‐binding site of S. aureus GyrB through a novel hydrogen bond with residue SER129. The molecule exhibits dual antibacterial and anticancer activity, supporting its potential as a dual‐target topoisomerase inhibitor.
Islam K. Matar +6 more
wiley +1 more source
Dual Combined Real-Time Reverse Transcription Polymerase Chain Reaction Assay for the Diagnosis of Lyssavirus Infection. [PDF]
The definitive diagnosis of lyssavirus infection (including rabies) in animals and humans is based on laboratory confirmation. The reference techniques for post-mortem rabies diagnosis are still based on direct immunofluorescence and virus isolation, but
Laurent Dacheux +8 more
doaj +1 more source
Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
wiley +1 more source
This case report demonstrates the successful diagnosis of a challenging paralytic rabies case using metagenomic next‐generation sequencing (mNGS). mNGS provided a rapid and precise pathogen identification directly from cerebrospinal fluid where traditional methods failed.
Lianghai Cao +6 more
wiley +1 more source
Understanding the transmission dynamics of rabies among dogs is crucial for designing effective control strategies in endemic regions. In this study, we developed and analyzed two deterministic compartmental models. The SEI model captures the natural progression of rabies in the absence of intervention, while the SEIV model incorporates vaccination ...
Md. Majharul Islam +3 more
wiley +1 more source
Australian Bat Lyssavirus Infection in a Captive Juvenile Black Flying Fox
The newly emerging Australian bat lyssavirus causes rabieslike disease in bats and humans. A captive juvenile black flying fox exhibited progressive neurologic signs, including sudden aggression, vocalization, dysphagia, and paresis over 9 days and then ...
Hume E. Field +2 more
doaj +1 more source
This study explores socioeconomic and health‐related aspects of a bat‐hunter community in Bangladesh, focusing on their unique cultural practices and the associated risks of bat‐borne infections. The hunter community predominantly engages in day labor and seasonal bat hunting as supplementary income.
A. K. M. Dawlat Khan, Hannah Wesley
wiley +1 more source
LYSSAVIRUS IN EPTESICUS SEROTINUS (CHIROPTERA: VESPERTILIONIDAE)
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Pérez-Jordá, Juan L. +3 more
openaire +3 more sources
In Germany, rabies in bats is a notifiable zoonotic disease, which is caused by European bat lyssaviruses type 1 and 2 (EBLV-1 and 2), and the recently discovered new lyssavirus species Bokeloh bat lyssavirus (BBLV). As the understanding of bat rabies in
Juliane Schatz +18 more
doaj +1 more source
Serologic Evidence of Lyssavirus Infection in Bats, Cambodia
In Cambodia, 1,303 bats of 16 species were tested for lyssavirus. No lyssavirus nucleocapsid was detected in 1,283 brains tested by immunofluorescence assay. Antibodies against lyssaviruses were detected by enzyme-linked immunosorbent assay in 144 (14.7%)
Jean-Marc Reynes +6 more
doaj +1 more source

