Results 61 to 70 of about 3,746 (167)

Coumarin‐Augmented Thiazole Hybrids as Dual Anticancer and Antibacterial Agents

open access: yesChemical Biology &Drug Design, Volume 107, Issue 2, February 2026.
Compound 13, a coumarin‐thiazole hybrid, is shown engaging the ATP‐binding site of S. aureus GyrB through a novel hydrogen bond with residue SER129. The molecule exhibits dual antibacterial and anticancer activity, supporting its potential as a dual‐target topoisomerase inhibitor.
Islam K. Matar   +6 more
wiley   +1 more source

Dual Combined Real-Time Reverse Transcription Polymerase Chain Reaction Assay for the Diagnosis of Lyssavirus Infection. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2016
The definitive diagnosis of lyssavirus infection (including rabies) in animals and humans is based on laboratory confirmation. The reference techniques for post-mortem rabies diagnosis are still based on direct immunofluorescence and virus isolation, but
Laurent Dacheux   +8 more
doaj   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N   +2 more
wiley   +1 more source

Diagnosis of Paralytic Rabies by Metagenomics Next‐Generation Sequencing: A Case Report and Review of the Literature

open access: yesVeterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This case report demonstrates the successful diagnosis of a challenging paralytic rabies case using metagenomic next‐generation sequencing (mNGS). mNGS provided a rapid and precise pathogen identification directly from cerebrospinal fluid where traditional methods failed.
Lianghai Cao   +6 more
wiley   +1 more source

Evaluating Pre‐ and Post‐Exposure Vaccination for Rabies Control in Dog Populations Using Mathematical Modeling

open access: yesAbstract and Applied Analysis, Volume 2026, Issue 1, 2026.
Understanding the transmission dynamics of rabies among dogs is crucial for designing effective control strategies in endemic regions. In this study, we developed and analyzed two deterministic compartmental models. The SEI model captures the natural progression of rabies in the absence of intervention, while the SEIV model incorporates vaccination ...
Md. Majharul Islam   +3 more
wiley   +1 more source

Australian Bat Lyssavirus Infection in a Captive Juvenile Black Flying Fox

open access: yesEmerging Infectious Diseases, 1999
The newly emerging Australian bat lyssavirus causes rabieslike disease in bats and humans. A captive juvenile black flying fox exhibited progressive neurologic signs, including sudden aggression, vocalization, dysphagia, and paresis over 9 days and then ...
Hume E. Field   +2 more
doaj   +1 more source

Bat Hunting, Illness, and Health‐Seeking Behavior Among a Bat‐Hunter Community in Bangladesh: Biomedical Versus Local Views

open access: yesAdvances in Public Health, Volume 2026, Issue 1, 2026.
This study explores socioeconomic and health‐related aspects of a bat‐hunter community in Bangladesh, focusing on their unique cultural practices and the associated risks of bat‐borne infections. The hunter community predominantly engages in day labor and seasonal bat hunting as supplementary income.
A. K. M. Dawlat Khan, Hannah Wesley
wiley   +1 more source

LYSSAVIRUS IN EPTESICUS SEROTINUS (CHIROPTERA: VESPERTILIONIDAE)

open access: yesJournal of Wildlife Diseases, 1995
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Pérez-Jordá, Juan L.   +3 more
openaire   +3 more sources

Enhanced passive bat rabies surveillance in indigenous bat species from Germany--a retrospective study.

open access: yesPLoS Neglected Tropical Diseases, 2014
In Germany, rabies in bats is a notifiable zoonotic disease, which is caused by European bat lyssaviruses type 1 and 2 (EBLV-1 and 2), and the recently discovered new lyssavirus species Bokeloh bat lyssavirus (BBLV). As the understanding of bat rabies in
Juliane Schatz   +18 more
doaj   +1 more source

Serologic Evidence of Lyssavirus Infection in Bats, Cambodia

open access: yesEmerging Infectious Diseases, 2004
In Cambodia, 1,303 bats of 16 species were tested for lyssavirus. No lyssavirus nucleocapsid was detected in 1,283 brains tested by immunofluorescence assay. Antibodies against lyssaviruses were detected by enzyme-linked immunosorbent assay in 144 (14.7%)
Jean-Marc Reynes   +6 more
doaj   +1 more source

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