Results 41 to 50 of about 3,575 (134)

New Lyssavirus Genotype from the Lesser Mouse-eared Bat (Myotis blythi), Kyrghyzstan

Emerging Infectious Diseases, 2003
The Aravan virus was isolated from a Lesser Mouse-eared Bat (Myotis blythi) in the Osh region of Kyrghyzstan, central Asia, in 1991. We determined the complete sequence of the nucleoprotein (N) gene and compared it with those of 26 representative ...
Yohko T. Arai, Ivan V. Kuzmin, Yosuke Kameoka, Alexandr D. Botvinkin   +3 more
doaj   +1 more source

Transcriptomic responses of bat cells to European bat lyssavirus 1 infection under conditions simulating euthermia and hibernation

BMC Immunology, 2023
Background Coevolution between pathogens and their hosts decreases host morbidity and mortality. Bats host and can tolerate viruses which can be lethal to other vertebrate orders, including humans.
Markéta Harazim, Juliette Perrot, Hugo Varet, Hervé Bourhy, Julien Lannoy, Jiri Pikula, Veronika Seidlová, Laurent Dacheux, Natália Martínková   +8 more
doaj   +1 more source

Coumarin‐Augmented Thiazole Hybrids as Dual Anticancer and Antibacterial Agents

Chemical Biology &Drug Design, Volume 107, Issue 2, February 2026.
Compound 13, a coumarin‐thiazole hybrid, is shown engaging the ATP‐binding site of S. aureus GyrB through a novel hydrogen bond with residue SER129. The molecule exhibits dual antibacterial and anticancer activity, supporting its potential as a dual‐target topoisomerase inhibitor.
Islam K. Matar, Magdi E. A. Zaki, Zeinab A. Muhammad, Dahlia A. Awwad, Sami A. Al‐Hussain, Chérif F. Matta, Refaie M. Kassab   +6 more
wiley   +1 more source

Temporal dynamics of European bat Lyssavirus type 1 and survival of Myotis myotis bats in natural colonies. [PDF]

PLoS ONE, 2007
Many emerging RNA viruses of public health concern have recently been detected in bats. However, the dynamics of these viruses in natural bat colonies is presently unknown.
Blanca Amengual, Hervé Bourhy, Marc López-Roig, Jordi Serra-Cobo   +3 more
doaj   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Diagnosis of Paralytic Rabies by Metagenomics Next‐Generation Sequencing: A Case Report and Review of the Literature

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This case report demonstrates the successful diagnosis of a challenging paralytic rabies case using metagenomic next‐generation sequencing (mNGS). mNGS provided a rapid and precise pathogen identification directly from cerebrospinal fluid where traditional methods failed.
Lianghai Cao, Xingyu Wang, Youlian Zhou, Jun Qiu, Qianlv Zeng, Chaogui Zhang, Lingai Pan   +6 more
wiley   +1 more source

Evaluating Pre‐ and Post‐Exposure Vaccination for Rabies Control in Dog Populations Using Mathematical Modeling

Abstract and Applied Analysis, Volume 2026, Issue 1, 2026.
Understanding the transmission dynamics of rabies among dogs is crucial for designing effective control strategies in endemic regions. In this study, we developed and analyzed two deterministic compartmental models. The SEI model captures the natural progression of rabies in the absence of intervention, while the SEIV model incorporates vaccination ...
Md. Majharul Islam, Md. Haider Ali Biswas, Md Hamidul Islam, Rosanna Manzo   +3 more
wiley   +1 more source

Bat rabies exposures and safety practices among a self-selecting sample of French bat handlers

IJID One Health
Objectives: European bats can be infected by several lyssaviruses, the causative agents of rabies. These viruses can be transmitted from bats to humans and result in a fatal viral encephalitis.
Julie Marmet, Laurent Dacheux, Katherine Worsley-Tonks, Evelyne Picard-Meyer, Hervé Bourhy, Perrine Parize   +5 more
doaj   +1 more source

Kinome-Wide RNA Interference Screening Identifies Mitogen-Activated Protein Kinases and Phosphatidylinositol Metabolism as Key Factors for Rabies Virus Infection

mSphere, 2019
Throughout the rabies virus (RABV) infectious cycle, host-virus interactions define its capacity to replicate, escape the immune response, and spread. As phosphorylation is a key regulatory mechanism involved in most cellular processes, kinases represent
Benoit Besson, Seonhee Kim, Taehee Kim, Yoonae Ko, Sangchul Lee, Florence Larrous, Jihwan Song, David Shum, Regis Grailhe, Hervé Bourhy   +9 more
doaj   +1 more source

Dual Combined Real-Time Reverse Transcription Polymerase Chain Reaction Assay for the Diagnosis of Lyssavirus Infection. [PDF]

PLoS Neglected Tropical Diseases, 2016
The definitive diagnosis of lyssavirus infection (including rabies) in animals and humans is based on laboratory confirmation. The reference techniques for post-mortem rabies diagnosis are still based on direct immunofluorescence and virus isolation, but
Laurent Dacheux, Florence Larrous, Rachel Lavenir, Anthony Lepelletier, Abdellah Faouzi, Cécile Troupin, Jalal Nourlil, Philippe Buchy, Herve Bourhy   +8 more
doaj   +1 more source