Results 21 to 30 of about 3,654 (170)

Molecular Characterization of Lyssaviruses Originating from Domestic and Wild Cats Provides an Insight on the Diversity of Lyssaviruses and a Risk of Rabies Transmission to Other Susceptible Mammals and Humans in South Africa

Pathogens, 2023
Rabies is one of the most significant public and veterinary health problems, causing approximately 59,000 human deaths annually in the developing countries of Asia and Africa.
Kefentse Tsie, Ernest Ngoepe, Baby Phahladira, Nelisiwe Khumalo, Claude Sabeta   +4 more
doaj   +1 more source

Lyssavirus matrix protein cooperates with phosphoprotein to modulate the Jak-Stat pathway

Scientific Reports, 2019
Phosphoprotein (P) and matrix protein (M) cooperate to undermine the immune response to rabies virus (RABV) infections. While P is involved in the modulation of the Jak-Stat pathway through the cytoplasmic retention of interferon (IFN)-activated STAT1 ...
Florian Sonthonnax, Benoit Besson, Emilie Bonnaud, Grégory Jouvion, David Merino, Florence Larrous, Hervé Bourhy   +6 more
doaj   +1 more source

Lyssavirus in Indian Flying Foxes, Sri Lanka

Emerging Infectious Diseases, 2016
A novel lyssavirus was isolated from brains of Indian flying foxes (Pteropus medius) in Sri Lanka. Phylogenetic analysis of complete virus genome sequences, and geographic location and host species, provides strong evidence that this virus is a putative ...
Panduka S. Gunawardena, Denise A. Marston, Richard J. Ellis, Emma L. Wise, Anjana C. Karawita, Andrew C. Breed, Lorraine M. McElhinney, Nicholas Johnson, Ashley Banyard, Anthony R. Fooks   +9 more
doaj   +1 more source

Machine Learning Identifies Cellular and Exosomal MicroRNA Signatures of Lyssavirus Infection in Human Stem Cell-Derived Neurons

Frontiers in Cellular and Infection Microbiology, 2021
Despite being vaccine preventable, rabies (lyssavirus) still has a significant impact on global mortality, disproportionally affecting children under 15 years of age.
Ryan J. Farr, Nathan Godde, Christopher Cowled, Vinod Sundaramoorthy, Diane Green, Cameron Stewart, John Bingham, Carmel M. O’Brien, Carmel M. O’Brien, Megan Dearnley   +9 more
doaj   +1 more source

Australian bat lyssavirus

Australian Journal of General Practice, 2018
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Merritt, Tony, Taylor, Kathryn, Cox-Witton, Keren, Field, Hume, Wingett, Kate, Mendez, Diana, Power, Michelle, Durrheim, David   +7 more
openaire   +7 more sources

Susceptibilities of CNS Cells towards Rabies Virus Infection Is Linked to Cellular Innate Immune Responses

Viruses, 2022
Rabies is caused by neurotropic rabies virus (RABV), contributing to 60,000 human deaths annually. Even though rabies leads to major public health concerns worldwide, we still do not fully understand factors determining RABV tropism and why glial cells ...
Lena Feige, Tatsuya Kozaki, Guilherme Dias de Melo, Vincent Guillemot, Florence Larrous, Florent Ginhoux, Hervé Bourhy   +6 more
doaj   +1 more source

Serologic Evidence of Lyssavirus Infections among Bats, the Philippines

Emerging Infectious Diseases, 2002
Active surveillance for lyssaviruses was conducted among populations of bats in the Philippines. The presence of past or current Lyssavirus infection was determined by use of direct fluorescent antibody assays on bat brains and virus neutralization ...
Paul M. Arguin, Kristy Murray-Lillibridge, Mary E.G. Miranda, Jean S. Smith, Alan B. Calaor, Charles E. Rupprecht   +5 more
doaj   +1 more source

Lyssavirus Detection and Typing Using Pyrosequencing [PDF]

Journal of Clinical Microbiology, 2011
ABSTRACT Rabies is a fatal zoonosis caused by a nonsegmented negative-strand RNA virus, namely, rabies virus (RABV). Apart from RABV, at least 10 additional species are known as rabies-related lyssaviruses (RRVs), and some of them are responsible for occasional spillovers into humans.
de Benedictis, Paola, de Battisti, Cristian, Dacheux, Laurent, Marciano, Sabrina, Ormelli, Silvia, Salomoni, Angela, Caenazzo, Silvia Tiozzo, Lepelletier, Anthony, Bourhy, Hervé, Capua, Ilaria, Cattoli, Giovanni   +10 more
openaire   +4 more sources

Molecular and serological survey of lyssaviruses in Croatian bat populations

BMC Veterinary Research, 2018
Background Rabies is the only known zoonotic disease of bat origin in Europe. The disease is caused by species belonging to the genus Lyssavirus. Five Lyssavirus species, i.e., European bat lyssavirus (EBLV)-1, EBLV-2, Bokeloh bat lyssavirus, Lleida bat ...
Ivana Šimić, Ivana Lojkić, Nina Krešić, Florence Cliquet, Evelyne Picard-Meyer, Marine Wasniewski, Anđela Ćukušić, Vida Zrnčić, Tomislav Bedeković   +8 more
doaj   +1 more source

A combination of two human monoclonal antibodies cures symptomatic rabies

EMBO Molecular Medicine, 2020
Rabies is a neglected disease caused by a neurotropic Lyssavirus, transmitted to humans predominantly by the bite of infected dogs. Rabies is preventable with vaccines or proper post‐exposure prophylaxis (PEP), but it still causes about 60,000 deaths ...
Guilherme Dias de Melo, Florian Sonthonnax, Gabriel Lepousez, Grégory Jouvion, Andrea Minola, Fabrizia Zatta, Florence Larrous, Lauriane Kergoat, Camille Mazo, Carine Moigneu, Roberta Aiello, Angela Salomoni, Elise Brisebard, Paola De Benedictis, Davide Corti, Hervé Bourhy   +15 more
doaj   +1 more source