Rabies is one of the most significant public and veterinary health problems, causing approximately 59,000 human deaths annually in the developing countries of Asia and Africa.
Kefentse Tsie +4 more
doaj +1 more source
The Phylogeography of Rabies in Grenada, West Indies, and Implications for Control [PDF]
In Grenada, West Indies, rabies is endemic, and is thought to be maintained in a wildlife host, the small Indian mongoose (Herpestes auropunctatus) with occasional spillover into other hosts.
Adelaide +17 more
core +4 more sources
Serological Evidence of Lyssaviruses among Bats on Southwestern Indian Ocean Islands.
We provide serological evidence of lyssavirus circulation among bats on southwestern Indian Ocean (SWIO) islands. A total of 572 bats belonging to 22 species were collected on Anjouan, Mayotte, La Réunion, Mauritius, Mahé and Madagascar and screened by ...
Julien Mélade +8 more
doaj +1 more source
From Bat to Worse: The Pivotal Role of Bats for Viral Zoonosis. [PDF]
Thanks to a dampened inflammatory innate immune response, various Chiropteran (bat) species frequently carry ‐ without showing symptoms – diverse viruses that can cause severe diseases in humans. The reasons why bats are a pivotal virus reservoir for emerging viral diseases are discussed in this Lilliput contribution.
Brüssow H.
europepmc +2 more sources
Application of high-throughput sequencing to whole rabies viral genome characterisation and its use for phylogenetic re-evaluation of a raccoon strain incursion into the province of Ontario [PDF]
Raccoon rabies remains a serious public health problem throughout much of the eastern seaboard of North America due to the urban nature of the reservoir host and the many challenges inherent in multi-jurisdictional efforts to administer co-ordinated and ...
Biek, Roman +4 more
core +1 more source
Lyssavirus matrix protein cooperates with phosphoprotein to modulate the Jak-Stat pathway
Phosphoprotein (P) and matrix protein (M) cooperate to undermine the immune response to rabies virus (RABV) infections. While P is involved in the modulation of the Jak-Stat pathway through the cytoplasmic retention of interferon (IFN)-activated STAT1 ...
Florian Sonthonnax +6 more
doaj +1 more source
Antigenic and genetic characterization of a divergent African virus, Ikoma lyssavirus [PDF]
In 2009, a novel lyssavirus (subsequently named Ikoma lyssavirus, IKOV) was detected in the brain of an African civet (Civettictis civetta) with clinical rabies in the Serengeti National Park of Tanzania.
Alejandro Nunez +21 more
core +2 more sources
Review of Rabies Preventions and Control [PDF]
Rabies is an acute viral infection of the central nervous system, caused by a lyssavirus in the family Rhabdoviridae. It is zoonotic viral disease that can affect all mammals, including humans, cats, dogs, and wildlife and farm animals.
Abdela, N. (Nejash) +1 more
core +2 more sources
Despite being vaccine preventable, rabies (lyssavirus) still has a significant impact on global mortality, disproportionally affecting children under 15 years of age.
Ryan J. Farr +9 more
doaj +1 more source
Frequency analysis of cytolytic T lymphocyte precursors (CTL-P) generated in vivo during lethal rabies infection of mice. II. Rabies virus genus specificity of CTL-P [PDF]
Cytolytic T lymphocyte precursors (CTL-P) were sensitized in vivo by intraplantar infection of C57BL/6 mice with a lethal dose of rabies virus, strain ERA (ERA).
Aden +22 more
core +1 more source

