Results 1 to 10 of about 3,746 (167)

Ikoma Lyssavirus, Highly Divergent Novel Lyssavirus in an African Civet

Emerging Infectious Diseases, 2012
Evidence in support of a novel lyssavirus was obtained from brain samples of an African civet in Tanzania. Results of phylogenetic analysis of nucleoprotein gene sequences from representative Lyssavirus species and this novel lyssavirus provided strong ...
Denise A. Marston, Daniel L. Horton, Chanasa Ngeleja, Katie Hampson, Lorraine M. McElhinney, Ashley C. Banyard, Daniel Haydon, Sarah Cleaveland, Charles E. Rupprecht, Machunde Bigambo, Anthony R. Fooks, Tiziana Lembo   +11 more
doaj   +6 more sources

Novel Lyssavirus in Bat, Spain

Emerging Infectious Diseases, 2013
A new tentative lyssavirus, Lleida bat lyssavirus, was found in a bent-winged bat (Miniopterus schreibersii) in Spain. It does not belong to phylogroups I or II, and it seems to be more closely related to the West Causasian bat virus, and especially to ...
Nidia Aréchiga Ceballos, Sonia Vázquez Morón, José M. Berciano, Olga Nicolás, Carolina Aznar López, Javier Juste, Cristina Rodríguez Nevado, Álvaro Aguilar Setién, Juan E. Echevarría   +8 more
doaj   +5 more sources

Evaluation of Taxonomic Characteristics of Matlo and Phala Bat Rabies-Related Lyssaviruses Identified in South Africa

Viruses, 2023
We report the genetic characterization of two potentially novel rabies-related lyssaviruses identified from bats in Limpopo province, South Africa. Matlo bat lyssavirus (MBLV) was identified in two Miniopterus natalensis (Natal long-fingered) bats in ...
Natalie Viljoen, Jacqueline Weyer, Jessica Coertse, Wanda Markotter   +3 more
doaj   +1 more source

Evaluation of Bioinformatically Designed, Historical Glycoproteins to Aid Pan-Lyssavirus Vaccine Development

International Journal of Infectious Diseases, 2022
Purpose: Without pre- or post-exposure prophylaxis, lyssaviruses cause rabies, an invariably fatal disease responsible for over 59,000 human deaths per year.
B. Auld, S. Frost, D. Wells, J. Heeney, A. Banyard, P. Schellenberger, E. Wright   +6 more
doaj   +1 more source

Lyssaviruses in Insectivorous Bats, South Africa, 2003–2018

Emerging Infectious Diseases, 2020
We detected 3 lyssaviruses in insectivorous bats sampled in South Africa during 2003–2018. We used phylogenetic analysis to identify Duvenhage lyssavirus and a potentially new lyssavirus, provisionally named Matlo bat lyssavirus, that is related to West ...
Jessica Coertse, Colyn S. Grobler, Claude T. Sabeta, Ernest C.J. Seamark, Teresa Kearney, Janusz T. Paweska, Wanda Markotter   +6 more
doaj   +1 more source

Attenuation of clinical and immunological outcomes during SARS‐CoV‐2 infection by ivermectin

EMBO Molecular Medicine, 2021
The devastating pandemic due to SARS‐CoV‐2 and the emergence of antigenic variants that jeopardize the efficacy of current vaccines create an urgent need for a comprehensive understanding of the pathophysiology of COVID‐19, including the contribution of ...
Guilherme Dias de Melo, Françoise Lazarini, Florence Larrous, Lena Feige, Etienne Kornobis, Sylvain Levallois, Agnès Marchio, Lauriane Kergoat, David Hardy, Thomas Cokelaer, Pascal Pineau, Marc Lecuit, Pierre‐Marie Lledo, Jean‐Pierre Changeux, Hervé Bourhy   +14 more
doaj   +1 more source

Molecular Characterization of Lyssaviruses Originating from Domestic and Wild Cats Provides an Insight on the Diversity of Lyssaviruses and a Risk of Rabies Transmission to Other Susceptible Mammals and Humans in South Africa

Pathogens, 2023
Rabies is one of the most significant public and veterinary health problems, causing approximately 59,000 human deaths annually in the developing countries of Asia and Africa.
Kefentse Tsie, Ernest Ngoepe, Baby Phahladira, Nelisiwe Khumalo, Claude Sabeta   +4 more
doaj   +1 more source

Lyssavirus matrix protein cooperates with phosphoprotein to modulate the Jak-Stat pathway

Scientific Reports, 2019
Phosphoprotein (P) and matrix protein (M) cooperate to undermine the immune response to rabies virus (RABV) infections. While P is involved in the modulation of the Jak-Stat pathway through the cytoplasmic retention of interferon (IFN)-activated STAT1 ...
Florian Sonthonnax, Benoit Besson, Emilie Bonnaud, Grégory Jouvion, David Merino, Florence Larrous, Hervé Bourhy   +6 more
doaj   +1 more source

Lyssavirus in Indian Flying Foxes, Sri Lanka

Emerging Infectious Diseases, 2016
A novel lyssavirus was isolated from brains of Indian flying foxes (Pteropus medius) in Sri Lanka. Phylogenetic analysis of complete virus genome sequences, and geographic location and host species, provides strong evidence that this virus is a putative ...
Panduka S. Gunawardena, Denise A. Marston, Richard J. Ellis, Emma L. Wise, Anjana C. Karawita, Andrew C. Breed, Lorraine M. McElhinney, Nicholas Johnson, Ashley Banyard, Anthony R. Fooks   +9 more
doaj   +1 more source

Machine Learning Identifies Cellular and Exosomal MicroRNA Signatures of Lyssavirus Infection in Human Stem Cell-Derived Neurons

Frontiers in Cellular and Infection Microbiology, 2021
Despite being vaccine preventable, rabies (lyssavirus) still has a significant impact on global mortality, disproportionally affecting children under 15 years of age.
Ryan J. Farr, Nathan Godde, Christopher Cowled, Vinod Sundaramoorthy, Diane Green, Cameron Stewart, John Bingham, Carmel M. O’Brien, Carmel M. O’Brien, Megan Dearnley   +9 more
doaj   +1 more source