Attenuation of palmitic acid-induced lysyl oxidase overexpression in the ovary contributes to the improvement of ovulation in obesity by metformin. [PDF]
Zhang C +7 more
europepmc +1 more source
Targeting lysyl oxidase like 2 attenuates OVA-induced airway remodeling partly via the AKT signaling pathway. [PDF]
Zeng R +11 more
europepmc +1 more source
Deletion of mouse lysyl oxidase in megakaryocytes affects bone properties in a sex-dependent manner.
Karagianni A +6 more
europepmc +1 more source
Sex differences and role of lysyl oxidase-like 2 in angiotensin II-induced hypertension in mice.
Wang H +12 more
europepmc +1 more source
Enhanced Optic Nerve Expansion and Altered Ultrastructure of Elastic Fibers Induced by Lysyl Oxidase Inhibition in a Mouse Model of Marfan Syndrome. [PDF]
Wu HJ +3 more
europepmc +1 more source
A molecular approach combined with American Thyroid Association classification better stratifies recurrence risk of classic histology papillary thyroid cancer [PDF]
Baranski, Thomas +8 more
core +1 more source
Identification of lysyl oxidase as an adipocyte-secreted mediator that promotes a partial mesenchymal-to-epithelial transition in MDA-MB-231 cells. [PDF]
Van Stiphout CM +6 more
europepmc +1 more source
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Lysyl Oxidases: Functions and Disorders
Journal of Glaucoma, 2018Lysyl oxidases (LOX) are copper-dependent enzymes that oxidize lysyl and hydroxylysyl residues in collagen and elastin, as a first step in the stabilization of these extracellular matrix proteins through the formation of covalent cross-linkages, an essential process for connective tissue maturation.
Fernando, Rodriguez-Pascual +1 more
openaire +2 more sources
Lysyl Oxidase and Lysyl Oxidase-Like Enzymes
2010Lysyl oxidase (LOX) and its four congeners, lysyl oxidase-like 1 (LOXL1), -2, -3, and -4, have received much investigative attention in recent years. LOX itself, is the prototypic form of these amine oxidase enzymes. LOX has long been considered to function exclusively as the enzyme that oxidizes peptidyl lysine in its collagen and elastin substrates ...
Herbert M. Kagan, Faina Ryvkin
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Lysyl Oxidase in Cancer Research
Future Oncology, 2014Metastasis is the main reason for cancer-associated deaths and therapies are desperately needed to target the progression of cancer. Lysyl oxidase (LOX) plays a pivotal role in cancer progression, including metastasis, and is therefore is an attractive therapeutic target.
Perryman, Lara, Erler, Janine Terra
openaire +3 more sources

