Characterization of an Indigenous Lytic Phage Targeting Multidrug-Resistant Salmonella enterica
Gut Microbes ReportsMultidrug-resistant pathogens have prompted the use of lytic bacteriophages. An indigenous novel lytic bacteriophage against Salmonella enterica strains from environmental wastewater was isolated and characterized using phage survivability study ...
Ebele Onuigbo +5 more
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Microscopy deep learning predicts virus infections and reveals mechanics of lytic-infected cells
iScience, 2021 Summary: Imaging across scales reveals disease mechanisms in organisms, tissues, and cells. Yet, particular infection phenotypes, such as virus-induced cell lysis, have remained difficult to study.
Vardan Andriasyan +6 more
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Distinguishing Lytic and Temperate Infection Dynamics in the Environment
VirusesViral infection and lysis drive bacterial diversity and abundances, ultimately regulating global biogeochemical cycles. Infection can follow lytic or temperate routes, with lytic dynamics suppressing bacterial population growth and temperate infection ...
Isha Tripathi +6 more
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Stepwise maturation of lytic granules during differentiation and activation of human CD8+ T lymphocytes. [PDF]
PLoS ONE, 2011 During differentiation, cytotoxic T lymphocytes (CTL) acquire their killing potential through the biogenesis and maturation of lytic granules that are secreted upon target cell recognition.
Yovan Sanchez-Ruiz +2 more
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Killing of Kaposi's sarcoma-associated herpesvirus-infected fibroblasts during latent infection by activated natural killer cells. [PDF]
, 2011 Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class-I ...
Nick C. Matthews +14 more
core +1 more source
International Journal of SurgeryLytic patellar lesions may occur in a variety of conditions, from commonly seen developmental, degenerative, traumatic, metabolic, infectious, iatrogenic to uncommon benign and malignant neoplasms. Patellar metastasis is rare. Due to the low incidence and the non-specific symptoms of metastatic anterior knee pain, delayed diagnosis is common and the ...
De-an Qin, Jie Yuan, Yan-Yan Dong
openaire +2 more sources
Painful Lytic Lesions of the Foot : A Case Report
, 2015 The presence of lytic lesions in the bones of foot raises a number of diagnostic possibilities ranging from infection, inflammatory pathology to neoplastic conditions.
R Vaishya, V Vijay, P Ghogare, A Vaish
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Functional Implications of Epstein-Barr Virus Lytic Genes in Carcinogenesis [PDF]
, 2022 Epstein-Barr virus (EBV) is associated with a diverse range of tumors of both lymphoid and epithelial origin. Similar to other herpesviruses, EBV displays a bipartite life cycle consisting of latent and lytic phases.
Lawrence S. Young +7 more
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AntibioticsBackground/Objectives: Escherichia coli (E. coli), a prevalent Gram-negative bacterium, is a frequent cause of illness. The extensive use of antibiotics has led to the emergence of resistant strains, complicating antimicrobial therapy and emphasizing the
Tasnime A. Abdo Ahmad +5 more
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Fine-Tuning of the Kaposi's Sarcoma-Associated Herpesvirus Life Cycle in Neighboring Cells through the RTA-JAG1-Notch Pathway. [PDF]
PLoS Pathogens, 2016 Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is an oncogenic pathogen that displays latent and lytic life cycles. In KS lesions, infiltrated immune cells, secreted viral and/or cellular cytokines, and hypoxia orchestrate a chronic pro-lytic ...
Shasha Li +5 more
doaj +1 more source