Cathepsin-L can resist lysis by human serum in Trypanosoma brucei brucei. [PDF]
Closely related African trypanosomes cause lethal diseases but display distinct host ranges. Specifically, Trypanosoma brucei brucei causes nagana in livestock but fails to infect humans, while Trypanosoma brucei gambiense and Trypanosoma brucei ...
Currier, Rachel B. +18 more
core +1 more source
Multifaceted Roles of ICP22/ORF63 Proteins in the Life Cycle of Human Herpesviruses
Herpesviruses are extremely successful parasites that have evolved over millions of years to develop a variety of mechanisms to coexist with their hosts and to maintain host-to-host transmission and lifelong infection by regulating their life cycles. The
Ying Wu +49 more
doaj +1 more source
Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo [PDF]
There is increasing evidence for a connection between DNA replication and the expression of adjacent genes. Therefore, this study addressed the question of whether a herpesvirus origin of replication can be used to activate or increase the expression of ...
Mohr, Hermine +47 more
core +2 more sources
Extracellular calcium reduction strongly increases the lytic capacity of pneumolysin from streptococcus pneumoniae in brain tissue [PDF]
Background. Streptococcus pneumoniae causes serious diseases such as pneumonia and meningitis. Its major pathogenic factor is the cholesterol-dependent cytolysin pneumolysin, which produces lytic pores at high concentrations.
Elke Maier +23 more
core +1 more source
Mucin and Agitation Shape Predation of Escherichia coli by Lytic Coliphage
The ability of bacteriophage (phage), abundant within the gastrointestinal microbiome, to regulate bacterial populations within the same micro-environment offers prophylactic and therapeutic opportunities.
Amanda Carroll-Portillo +7 more
doaj +1 more source
Cyclic GMP signaling during the lytic cycle of Toxoplasma gondii [PDF]
Der cGMP-Signalweg ist als einer der Hauptregulatoren von diversen Funktionen in Eukaryoten bekannt; allerdings ist seine Funktionsweise in Protozoen wenig verstanden.
Günay-Esiyok, Özlem
core +1 more source
Moderate Seasonal Dynamics Indicate an Important Role for Lysogeny in the Red Sea
Viruses are the most abundant microorganisms in marine environments and viral infections can be either lytic (virulent) or lysogenic (temperate phage) within the host cell. The aim of this study was to quantify viral dynamics (abundance and infection) in
Ruba Abdulrahman Ashy +2 more
doaj +1 more source
The interaction between gut bacterial and viral microbiota is thought to be important in human health. While fluctuations in female genital tract (FGT) bacterial microbiota similarly determine sexual health, little is known about the presence ...
Anna-Ursula Happel +10 more
doaj +1 more source
Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by Trypanolytic factor 1 [PDF]
<p><b>Background:</b> The three sub-species of <i>Trypanosoma brucei</i> are important pathogens of sub-Saharan Africa. <i>T. b.
C. Michael R. Turner +30 more
core +1 more source
Exploring Antimicrobial Peptides Efficacy against Fire Blight (Erwinia amylovora)
Antimicrobial peptides (AMPs) are a various group of molecules found in a wide range of organisms and act as a defense mechanism against different kinds of infectious pathogens (bacteria, viruses, and fungi, etc.).
Miloud Sabri +6 more
doaj +1 more source

