Results 1 to 10 of about 152,902 (307)

Epstein–Barr Virus: How Its Lytic Phase Contributes to Oncogenesis

open access: yesMicroorganisms, 2020
Epstein–Barr Virus (EBV) contributes to the development of lymphoid and epithelial malignancies. While EBV’s latent phase is more commonly associated with EBV-associated malignancies, there is increasing evidence that EBV’s lytic phase plays a role in ...
Quincy Rosemarie   +2 more
exaly   +4 more sources

Locus-specific proteomics identifies novel regulators of Epstein-Barr virus lytic reactivation [PDF]

open access: yesJournal of Virology
The Epstein-Barr virus (EBV) is a human gamma-herpesvirus which infects over 90% of the global population and is associated with lymphoid and epithelioid cancers. After infection, EBV enters a latent state in B cells, whereby the viral genome persists as
Daniel E. Greaves   +8 more
doaj   +2 more sources

The role of bacteriophages in shaping bacterial composition and diversity in the human gut

open access: yesFrontiers in Microbiology, 2023
The microbiota of the gut has continued to co-evolve alongside their human hosts conferring considerable health benefits including the production of nutrients, drug metabolism, modulation of the immune system, and playing an antagonistic role against ...
Samia S. Alkhalil
doaj   +1 more source

Unknown Extracellular and Bioactive Metabolites of the Genus Alexandrium: A Review of Overlooked Toxins

open access: yesToxins, 2021
Various species of Alexandrium can produce a number of bioactive compounds, e.g., paralytic shellfish toxins (PSTs), spirolides, gymnodimines, goniodomins, and also uncharacterised bioactive extracellular compounds (BECs).
Marc Long   +3 more
doaj   +1 more source

Targeting the BMP Pathway in Prostate Cancer Induced Bone Disease

open access: yesFrontiers in Endocrinology, 2021
From the 33,000 men in the U.S. who die from prostate cancer each year, the majority of these patients exhibit metastatic disease with bone being the most common site of metastasis.
Desiree M. Straign   +5 more
doaj   +1 more source

A Rare Case of Rosai-Dorfman Disease in Calcaneum and Study of Literature [PDF]

open access: yesJournal of Foot and Ankle Surgery (Asia Pacific), 2021
Background: Pain and osteolytic lesions on X-rays with non-specific changes on histopathology and negative culture are common scenarios; patients often treated with empirical antibiotics or anti-tuberculosis therapy (ATT), especially in regions where ...
Amit Gupta   +4 more
doaj   +1 more source

Isolation, characterization, and application of a novel polyvalent lytic phage STWB21 against typhoidal and nontyphoidal Salmonella spp.

open access: yesFrontiers in Microbiology, 2022
Salmonella is one of the common causal agents of bacterial gastroenteritis-related morbidity and mortality among children below 5 years and the elderly populations.
Payel Mondal   +3 more
doaj   +1 more source

Targeting Host Cellular Factors as a Strategy of Therapeutic Intervention for Herpesvirus Infections

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Herpesviruses utilize various host factors to establish latent infection, survival, and spread disease in the host. These factors include host cellular machinery, host proteins, gene expression, multiple transcription factors, cellular signal pathways ...
Kumari Asha, Neelam Sharma-Walia
doaj   +1 more source

Replication Region Analysis Reveals Non-lambdoid Shiga Toxin Converting Bacteriophages

open access: yesFrontiers in Microbiology, 2021
Shiga toxin is the major virulence factor of enterohemorrhagic Escherichia coli (EHEC), and the gene encoding it is carried within the genome of Shiga toxin-converting phages (Stx phages).
Ann-Katrin Llarena   +4 more
doaj   +1 more source

Characterization of N4-like Pseudomonas Phage vB_Pae-PA14 Isolated from Seawater Sampled in Thailand

open access: yesJournal of Pure and Applied Microbiology, 2021
Bacteriophage, a predator virus of bacteria, is an abundant biological entity in the biosphere. With ultimate applications in medicine and biotechnology, new phages are extensively being isolated and characterized.
Akkaraphol Srichaisupakit   +2 more
doaj   +1 more source

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