Results 1 to 10 of about 165,472 (305)
Epstein–Barr Virus: How Its Lytic Phase Contributes to Oncogenesis
Microorganisms, 2020 Epstein–Barr Virus (EBV) contributes to the development of lymphoid and epithelial malignancies. While EBV’s latent phase is more commonly associated with EBV-associated malignancies, there is increasing evidence that EBV’s lytic phase plays a role in ...
Quincy Rosemarie, Bill Sugden
exaly +4 more sources
The role of bacteriophages in shaping bacterial composition and diversity in the human gut
Frontiers in Microbiology, 2023 The microbiota of the gut has continued to co-evolve alongside their human hosts conferring considerable health benefits including the production of nutrients, drug metabolism, modulation of the immune system, and playing an antagonistic role against ...
Samia S. Alkhalil
doaj +1 more source
Regulation of Lytic and Non-Lytic Functions of Gasdermin Pores
Journal of Molecular Biology, 2022 Pyroptosis is a necrotic form of cell death that was initially found to be induced upon activation of inflammatory caspases by inflammasome complexes. Mechanistically, pyroptosis induction requires cleavage of the caspase substrate gasdermin D (GSDMD), and the release of the GSDMD N-terminal fragment, which targets the plasma membrane to form large β ...
Rühl, Sebastian, Broz, Petr
openaire +2 more sources
Targeting Host Cellular Factors as a Strategy of Therapeutic Intervention for Herpesvirus Infections
Frontiers in Cellular and Infection Microbiology, 2021 Herpesviruses utilize various host factors to establish latent infection, survival, and spread disease in the host. These factors include host cellular machinery, host proteins, gene expression, multiple transcription factors, cellular signal pathways ...
Kumari Asha, Neelam Sharma-Walia
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Replication Region Analysis Reveals Non-lambdoid Shiga Toxin Converting Bacteriophages
Frontiers in Microbiology, 2021 Shiga toxin is the major virulence factor of enterohemorrhagic Escherichia coli (EHEC), and the gene encoding it is carried within the genome of Shiga toxin-converting phages (Stx phages).
Ann-Katrin Llarena +4 more
doaj +1 more source
Characterization of N4-like Pseudomonas Phage vB_Pae-PA14 Isolated from Seawater Sampled in Thailand
Journal of Pure and Applied Microbiology, 2021 Bacteriophage, a predator virus of bacteria, is an abundant biological entity in the biosphere. With ultimate applications in medicine and biotechnology, new phages are extensively being isolated and characterized.
Akkaraphol Srichaisupakit +2 more
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Microbiology Spectrum, 2021 Viruses exert diverse ecosystem impacts by controlling their host community through lytic predator-prey dynamics. However, the mechanisms by which lysogenic viruses influence their host-microbial community are less clear.
Sergio Guajardo-Leiva +5 more
doaj +1 more source
A Rare Case of Rosai-Dorfman Disease in Calcaneum and Study of Literature [PDF]
Journal of Foot and Ankle Surgery (Asia Pacific), 2021 Background: Pain and osteolytic lesions on X-rays with non-specific changes on histopathology and negative culture are common scenarios; patients often treated with empirical antibiotics or anti-tuberculosis therapy (ATT), especially in regions where ...
Amit Gupta +4 more
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Rare case of isolated distal radius tubercular osteomyelitis
Journal of Bone and Joint Diseases, 2023 Osteoarticular tuberculosis is the third most frequent location of tuberculosis after the lung and lymph nodes, accounting for approximately 10%–20% of all cases of extrapulmonary disease.
Yasir Salam Siddiqui +5 more
doaj +1 more source
Proceedings, 2020 Herpesviruses usurp host cell protein synthesis machinery to convert viral mRNAs into proteins, and the endoplasmic reticulum (ER) to ensure the proper folding, post-translational modification and trafficking of secreted and transmembrane viral proteins.
Benjamin P. Johnston +2 more
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