Results 11 to 20 of about 152,902 (307)
Phage lytic enzymes are enzymes produced by bacterial viruses, either as part of their virion to facilitate bacterial infection through local peptidoglycan degradation, or as soluble proteins to induce massive cell lysis at the end of the lytic replication cycle [...]
Yves Briers, Briers, Yves
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Although cleaving the same glycosidic bond between MurNAc and GlcNAc in murein, lytic transglycosylases differ from lysozymes by catalyzing an intramolecular transglycosylation of the glycosyl-bond onto the C6 hydroxyl group of the muramic acid residue yielding 1.6-anhydromuramic acid-carrying products.
Höltje, J., J.-V. Höltje
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Isolation and Characterization of Lytic Coliphages from Sewage Water
The goal of this study was to isolate and characterize phages that might be used in transport and treatment of potential E.coli pathogen in water sources.
P.U. Megha, S. Murugan, P.S. Harikumar
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K13 blocks KSHV lytic replication and deregulates vIL6 and hIL6 expression: a model of lytic replication induced clonal selection in viral oncogenesis. [PDF]
Accumulating evidence suggests that dysregulated expression of lytic genes plays an important role in KSHV (Kaposi's sarcoma associated herpesvirus) tumorigenesis.
Jinshun Zhao +8 more
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Can non-lytic CD8+ T cells drive HIV-1 escape? [PDF]
The CD8+ T cell effector mechanisms that mediate control of HIV-1 and SIV infections remain poorly understood. Recent work suggests that the mechanism may be primarily non-lytic.
Nafisa-Katrin Seich Al Basatena +5 more
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Regulation of Lytic and Non-Lytic Functions of Gasdermin Pores
Pyroptosis is a necrotic form of cell death that was initially found to be induced upon activation of inflammatory caspases by inflammasome complexes. Mechanistically, pyroptosis induction requires cleavage of the caspase substrate gasdermin D (GSDMD), and the release of the GSDMD N-terminal fragment, which targets the plasma membrane to form large β ...
Rühl, Sebastian, Broz, Petr
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Viruses exert diverse ecosystem impacts by controlling their host community through lytic predator-prey dynamics. However, the mechanisms by which lysogenic viruses influence their host-microbial community are less clear.
Sergio Guajardo-Leiva +5 more
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Rare case of isolated distal radius tubercular osteomyelitis
Osteoarticular tuberculosis is the third most frequent location of tuberculosis after the lung and lymph nodes, accounting for approximately 10%–20% of all cases of extrapulmonary disease.
Yasir Salam Siddiqui +5 more
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Herpesviruses usurp host cell protein synthesis machinery to convert viral mRNAs into proteins, and the endoplasmic reticulum (ER) to ensure the proper folding, post-translational modification and trafficking of secreted and transmembrane viral proteins.
Benjamin P. Johnston +2 more
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Immunodominance of lytic cycle antigens in Epstein-Barr virus-specific CD4+ T cell preparations for therapy. [PDF]
Epstein-Barr virus (EBV) is associated with a number of human malignancies. EBV-positive post-transplant lymphoproliferative disease in solid organ and hematopoietic stem cell transplant recipients has been successfully treated by the adoptive transfer ...
Burdach, S. +36 more
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