Stage-Specific Inhibition of MHC Class I Presentation by the Epstein-Barr Virus BNLF2a Protein during Virus Lytic Cycle [PDF]
gamma-herpesvirus Epstein-Barr virus (EBV) persists for life in infected individuals despite the presence of a strong immune response. During the lytic cycle of EBV many viral proteins are expressed, potentially allowing virally infected cells to be ...
A Rickinson+51 more
core +25 more sources
Lytic Cycle ofToxoplasma gondii [PDF]
SUMMARYToxoplasma gondii is an obligate intracellular pathogen within the phylum Apicomplexa. This protozoan parasite is one of the most widespread, with a broad host range including many birds and mammals and a geographic range that is nearly worldwide.
Michael W. Black, John C. Boothroyd
openalex +4 more sources
The Induction of the Lytic Cycle in Lysogenic Bacteria by Phagolessin A 58 [PDF]
SUMMARY: Phagolessin A58, an antibiotic having antiphage activity, was found to have an action which induced the lytic cycle in some strains of lysogenic bacteria. Four different lysogenic organisms were tested: Bacillus megaterium 899; Escherichia coli FCb; E. coli Temple; E. coli Lampert.
E. Hall-Asheshov, Igor N. Asheshov
openalex +4 more sources
Mitochondrial behaviour throughout the lytic cycle of Toxoplasma gondii [PDF]
Mitochondria distribution in cells controls cellular physiology in health and disease. Here we describe the mitochondrial morphology and positioning found in the different stages of the lytic cycle of the eukaryotic single-cell parasite Toxoplasma gondii.
Lemgruber, Leandro+4 more
core +6 more sources
The activation of KSHV lytic cycle blocks autophagy in PEL cells [PDF]
This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression.
CIRONE, Mara+7 more
core +5 more sources
Contribution of the KSHV and EBV lytic cycles to tumourigenesis [PDF]
Kaposi's Sarcoma-associated herpesvirus (KSHV) and Epstein Barr virus (EBV) are the causative agents of several malignancies. Like all herpesviruses, KSHV and EBV undergo distinct latent and lytic replication programmes. The transition between these states allows the establishment of a lifelong persistent infection, dissemination to sites of disease ...
Oliver Manners+4 more
openalex +5 more sources
Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency [PDF]
Herpesviruses are characterized as having two distinct life cycle phases: lytic replication and latency. The mechanisms of latency establishment and maintenance, as well as the switch from latency to lytic replication, are poorly understood.
Nash, A A+4 more
core +3 more sources
ARID3B: A novel regulator of the Kaposi's sarcoma-associated herpesvirus lytic cycle [PDF]
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of commonly fatal malignancies of immunocompromised individuals, including primary effusion lymphoma (PEL) and Kaposi's sarcoma (KS).
Boyne, JR+6 more
core +8 more sources
Herpesvirus Lytic Replication and the Cell Cycle: Arresting New Developments [PDF]
It has been clear for a number of years that small DNA tumor viruses such as simian virus 40 (SV40) and papillomavirus interact with cell cycle control pathways during lytic replication in a way that promotes entry into the S phase of the cell cycle.
Erik K. Flemington
openalex +3 more sources
Lytic cycle: A defining process in oncolytic virotherapy [PDF]
The viral lytic cycle is an important process in oncolytic virotherapy. Most mathematical models for oncolytic virotherapy do not incorporate this process.
Tian, Jianjun Paul+3 more
core +4 more sources