Results 101 to 110 of about 100,112 (246)

Calculating Biological Behaviors of Epigenetic States in Phage lambda Life Cycle [PDF]

open access: yes, 2004
Gene regulatory network of lambda phage is one the best studied model systems in molecular biology. More 50 years of experimental study has provided a tremendous amount of data at all levels: physics, chemistry, DNA, protein, and function.
Ao, P., Hood, L., Yin, L., Zhu, X. -M.
core   +1 more source

Promising Prodiginins Biological Activities

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto   +6 more
wiley   +1 more source

Morphological Profiling of Imaging Flow Cytometry Data Uncovers Heterogeneity in Infected Gephyrocapsa huxleyi Cultures

open access: yesCytometry Part A, EarlyView.
ABSTRACT Phytoplankton, such as the coccolitophore Gephyrocapsa huxleyi (G. huxleyi), has a major ecological impact through photosynthesis—the production of oxygen and organic material. A significant threat to G. huxleyi populations is viral infection with the specific Gephyrocapsa huxleyi virus (GhV).
Maxim Lippeveld   +4 more
wiley   +1 more source

LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection. [PDF]

open access: yesPLoS Pathogens, 2016
One of the hallmarks of the latent phase of Kaposi's sarcoma-associated herpesvirus (KSHV) infection is the global repression of lytic viral gene expression.
Zsolt Toth   +5 more
doaj   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

open access: yesExploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang   +4 more
wiley   +1 more source

Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes [PDF]

open access: yes, 2017
BACKGROUND: Monocytes/macrophages are activated in several autoimmune diseases, including systemic sclerosis (scleroderma; SSc), with increased expression of interferon (IFN)-regulatory genes and inflammatory cytokines, suggesting dysregulation of the ...
Dreyfus, David H.   +12 more
core   +1 more source

Ovine herpesvirus 2 lytic cycle replication and capsid production

open access: yesJournal of General Virology, 2002
Ovine herpesvirus 2 (OvHV-2) causes malignant catarrhal fever in cattle, pigs and deer. We have observed intact circular and linear OvHV-2 genomes in infected T cell lines derived from cows and rabbits. Bovine T cell lines were predominantly latently infected but rabbit T cell lines supported OvHV-2 productive cycle gene expression and virus capsids ...
Robert G. Dalziel   +3 more
openaire   +3 more sources

Anti‐Pseudomonas Aeruginosa Bacteriophage Loaded Electrospun Fibers for Antibacterial Wound Dressings

open access: yesMacromolecular Rapid Communications, EarlyView.
Multidrug resistant Pseudomonas (P.) aeruginosa is detected in many infected wounds and is challenging to treat with antibiotics. As an alternative, this work incorporates anti‐P. aeruginosa Neko phages into electrospun fibres to explore their potential for treating infected wounds.
Tian Ju   +7 more
wiley   +1 more source

Epstein-Barr Virus Exploits the Secretory Pathway to Release Virions

open access: yesMicroorganisms, 2020
Herpesvirus egress mechanisms are strongly associated with intracellular compartment remodeling processes. Previously, we and other groups have described that intracellular compartments derived from the Golgi apparatus are the maturation sites of Epstein-
Asuka Nanbo
doaj   +1 more source

Mechanism of activation of the BNLF2a immune evasion gene of Epstein-Barr virus by Zta [PDF]

open access: yes, 2018
The human gamma herpes virus Epstein–Barr virus (EBV) exploits multiple routes to evade the cellular immune response. During the EBV lytic replication cycle, viral proteins are expressed that provide excellent targets for recognition by cytotoxic T cells.
Alison J. Sinclair   +17 more
core   +3 more sources

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