Results 111 to 120 of about 100,112 (246)

A Kinetic Model of Antigen‐Dependent IgG Oligomerization and Complement Binding

open access: yesSmall Science, EarlyView.
A kinetic model capable of predicting IgG oligomerization, a key step in activating the classical complement pathway (CCP) of the immune system, is presented. The impacts of IgG subclass, concentration, and antigen density are analyzed using advanced biophysical techniques.
Jürgen Strasser   +7 more
wiley   +1 more source

Boolean Models of Bistable Biological Systems

open access: yes, 2009
This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model.
A. Novick   +16 more
core   +1 more source

Metastatic intrigue: Penile involvement in prostate cancer with neuroendocrine differentiation—A case report

open access: yesUroPrecision, EarlyView.
Abstract Background Neuroendocrine carcinoma of the prostate is a rare tumor subtype found in the spectrum of prostate cancer, and is more difficult to detect, due to the low prostate‐specific antigen values associated with it. A high degree of suspicion is hence needed to arrive at the diagnosis in such cases.
Uttam Kumar Mete   +3 more
wiley   +1 more source

Deteksi Gen Litik BRLF1 Epstein-Barr Virus pada Penderita Karsinoma Nasofaring

open access: yesMajalah Ilmiah Biologi Biosfera: A Scientific Journal, 2018
Rosenmuller fossa. Epithelial malignancy is often found in Chinese populations and Southeast Asia including Indonesia. Undifferentiated nasopharyngeal carcinoma (NPC WHO-3) type is 100% associated with Epstein-Barr virus (EBV) infection.
Tri Yulia Ningsih   +2 more
doaj   +1 more source

Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]

open access: yes, 2018
The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epstein⁻Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.
Chen, Yuan-Chuan   +3 more
core   +2 more sources

Effects of Calcium on the Lytic Cycle of Bacillus subtilis Phage 41c

open access: yesJournal of General Virology, 1980
The lytic cycle of Bacillus subtilis phage 41c required the presence of at least 10 mM-calcium. In the absence of this ion, the plaquing efficiency of the virus was reduced to less than 0.1. Likewise, replacement of Ca2+ with other divalent ions (Ba2+, Sr2+, Mg2+, Mn2+) resulted in reduced efficiencies.
Robert M. Zsigray, Edward F. Landry
openaire   +3 more sources

Long‐term survival in a dog with suspected primary nodal plasmacytoma treated with surgical excision

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract An 8‐year‐old Staffordshire bull terrier presented for left submandibular lymphadenopathy. Cytology showed a monomorphic population of mature plasma cells suggestive of plasma cell neoplasia. On physical examination, no other lymphadenomegaly, cutaneous or oral lesions were found.
Celia Figueroa‐González   +4 more
wiley   +1 more source

Kaposi's sarcoma-associated herpesvirus vIRF2 protein utilizes an IFN-dependent pathway to regulate viral early gene expression.

open access: yesPLoS Pathogens, 2019
Kaposi's sarcoma-associated herpesvirus (KSHV; human herpesvirus 8) belongs to the subfamily of Gammaherpesvirinae and is the etiological agent of Kaposi's sarcoma as well as of two lymphoproliferative diseases: primary effusion lymphoma and multicentric
Sandra Koch   +11 more
doaj   +1 more source

The Epstein-Barr Virus Episome Maneuvers between Nuclear Chromatin Compartments during Reactivation. [PDF]

open access: yes, 2018
The human genome is structurally organized in three-dimensional space to facilitate functional partitioning of transcription. We learned that the latent episome of the human Epstein-Barr virus (EBV) preferentially associates with gene-poor chromosomes ...
Fernandez, Samantha G   +7 more
core   +1 more source

The effect of Astragalus polysaccharide on the Epstein-Barr virus lytic cycle

open access: yesActa virologica, 2014
Effects of a polysacharide from Chinese herbal plant Astragalus membranaceus (APS) on the expression of Epstein-Barr virus (EBV) immediate early proteins Zta, Rta and EA-D in Raji cells were examined. EBV switch from latent to lytic cycle in Raji cells was induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) and sorbol butyrate (SB) and the effects of
Q Guo   +8 more
openaire   +4 more sources

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