Results 111 to 120 of about 106,964 (291)
Equine Veterinary Journal, EarlyView.Abstract Background Condylar stress fracture of the third metacarpal bone (MC3) is a common catastrophic injury in Thoroughbred racehorses and is associated with parasagittal groove (PSG) subchondral osteolysis. Standing computed tomography (sCT) imaging enables sensitive identification of this fatigue‐induced early subchondral bone injury (SBI), but ...
Nicola L. Brown +5 more
wiley +1 more source
Herpesviral Latency—Common Themes
Pathogens, 2020 Latency establishment is the hallmark feature of herpesviruses, a group of viruses, of which nine are known to infect humans. They have co-evolved alongside their hosts, and mastered manipulation of cellular pathways and tweaking various processes to ...
Magdalena Weidner-Glunde +2 more
doaj +1 more source
Boolean Models of Bistable Biological Systems
, 2009 This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model.
A. Novick +16 more
core +1 more source
Mechanism of activation of the BNLF2a immune evasion gene of Epstein-Barr virus by Zta [PDF]
, 2018 The human gamma herpes virus Epstein–Barr virus (EBV) exploits multiple routes to evade the cellular immune response. During the EBV lytic replication cycle, viral proteins are expressed that provide excellent targets for recognition by cytotoxic T cells.
Alison J. Sinclair +17 more
core +3 more sources
Head &Neck, EarlyView.ABSTRACT Background Cutaneous adnexal carcinomas are a very rare group of cancers arising from appendageal structures of the skin. More than half occur in the head and neck region. No standard treatments exist for metastatic disease. Methods A 48‐year‐old postmenopausal female presented with an enlarging scalp lesion.
Nilesh Kapoor +3 more
wiley +1 more source
KSHV Targeted Therapy: An Update on Inhibitors of Viral Lytic Replication
Viruses, 2014 Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi’s sarcoma, primary effusion lymphoma and multicentric Castleman’s disease.
Natacha Coen +3 more
doaj +1 more source
iMetaOmics, EarlyView.Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo +9 more
wiley +1 more source
Short-term inhibition of TERT induces telomere length-independent cell cycle arrest and apoptotic response in EBV-immortalized and transformed B cells [PDF]
, 2016 open7siBesides its canonical role in stabilizing telomeres, telomerase reverse transcriptase (TERT) may promote tumorigenesis through extra-telomeric functions.
Celeghin, Andrea +6 more
core +1 more source
Antimicrobial Cyclic Peptidomimetics
Macromolecular Rapid Communications, EarlyView.Singular macromolecular cationic, amphipathic cyclic peptidomimetics with poly(2‐oxazoline)s‐esque backbone structure that undergo self‐assembly in water to form uniform nanoparticles were developed. The cyclic peptidomimetics, which act on bacterial cell membranes, exhibit hydrophobic‐dependent antimicrobial activity and toxicity.
Hao Luo, Edgar H. H. Wong
wiley +1 more source
International Journal of Osteoarchaeology, EarlyView.ABSTRACT This study aims to identify lesions confined to the internal structures of bones. A radiographic analysis was performed on 219 archaeological, historical period skeletons from southern Finland. Although the study examines nearly all preserved skeletal elements using plain radiographs, it does not incorporate computed tomography.
Kati Salo +2 more
wiley +1 more source